DOI QR코드

DOI QR Code

당뇨전단계 성인의 비만이 당뇨병 발생 위험에 미치는 영향: 전향적 코호트 자료의 활용

Incidence of Obesity-related Diabetes Mellitus in Adults with Prediabetes: Use of Data from a Prospective Cohort Study

  • Han, Nara (Operating Room, Jeonbuk National University Hospital) ;
  • Cho, HyangSoon (College of Nursing, Jeonbuk National University) ;
  • Ju, Jeong Suk (Intensive Care Unit, Wonkwang University Hospital) ;
  • Lee, Kyoung Mee (Gunsanjeonbuk National University Hospital Construction)
  • 투고 : 2023.03.08
  • 심사 : 2023.09.05
  • 발행 : 2023.11.30

초록

Purpose: The purpose of this study was to identify the impact of obesity on the incidence of diabetes mellitus in adults with pre-diabetes. Methods: This study employed a longitudinal study design and utilized secondary data drawn from the Korean Genome and Epidemiology Study. This study used data from a sample of 3,693 adults with prediabetes who were followed every two years from 2001 to 2018. Statistical data analysis for frequency, number of cases per 1,000 person-years, log-rank test, Kaplan-Meier curve, and Cox's proportional hazards regression analysis was performed using IBM SPSS statistics version 26. Results: During the observation period, there were 1,309 (35.4%) patients with diabetes, and the total number of person-years was 35,342. The incidence of diabetes was higher in the obese group compared to the normal weight group (body mass index [BMI]: hazard ratio=1.57, 95% confidence interval [CI]=1.40~1.77, waist: hazard ratio=1.55, 95% CI=1.38~1.76, waist to hip ratio [WHR]: hazard ratio=1.53, 95% CI=1.24~1.89, body fat [BF] (%): hazard ratio=1.42, 95% CI=1.27~1.61). Conclusion: An increase in BMI, waist circumference, and WHR, which are indicators of obesity, can exacerbate the risk factors for diabetes. Thus, a decrease in BMI, waist circumference, and WHR is necessary to prevent pre-diabetes. In particular, health care professionals should provide individualized weight management program interventions, including adult obesity programs and obesity counseling in partnership with local health departments, to reduce BMI and waist circumference in people at high risk for diabetes.

키워드

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