The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
권호 표지
DOI QR코드

DOI QR Code

A Case Report on the Complete Response of a Patient with Recurrent Follicular Lymphoma Treated with Integrative Medicine

한양방통합치료를 병행 후 완치된 재발성 소포림프종 증례 보고

  • Received : 2023.05.30
  • Accepted : 2023.07.05
  • Published : 2023.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objective: The purpose of this study is to report the effect of integrative medicine on recurrent follicular lymphoma, thus providing a clinical basis for integrative medicine. Methods: The medical report of a patient with follicular lymphoma who had undergone several chemotherapies but continuously relapsed before treated with integrative medicine was analyzed. Radiologic outcome was assessed by several imaging tests based on Response Evaluation Criteria in Solid Tumors. Clinical outcome and safety were assessed by laboratory tests. Results: After five years of integrative treatment, there was a complete response in imaging tests such as computed tomography (CT), positron-emission tomography/CT, and endoscopy. There were no toxicity in the laboratory test and no serious side effect of integrative medicine. Conclusion: This study suggested that integrative medicine has few side effects but significant effects on treating recurrent follicular lymphoma. However, the results should be taken cautiously as further clinical studies are needed.

Keywords

References

  1. Kim MJ, Hwang HS, Cho HW, Yoon DH, Suh CW, Park CS, et al. Upward trend in follicular lymphoma among the Korean population: 10-year experience at a large tertiary institution. Journal of Pathology and Translational Medicine 2021;55(5):330-7.  https://doi.org/10.4132/jptm.2021.07.25
  2. Jacobsen E. Follicular lymphoma: 2023 update on diagnosis and management. American Journal of Hematology 2022;97(12):1639-51.  https://doi.org/10.1002/ajh.26737
  3. Freedman A. Follicular lymphoma: 2018 update on diagnosis and management. Am J Hematol 2018;93(2):296-305.  https://doi.org/10.1002/ajh.24937
  4. Kim YS, Yoon SW. Herb medications on angiocentric T-cell lymphoma with intra-abdominal metastasis: a case report. J of Kor Oriental Oncology 2005;10(1):93-8. 
  5. Choi SH, Song AN, An JH, Kim EH, Park SJ, Kim KS, et al. A Case Study of Soeumin with Peripheral T-cell Lymphoma who Showed Symptomatic Improvement including Fever, Myalgia, Performance Status, and Headache after Treated with Osuyubujaijung-tang and Geopoong-san. J Sasang Constitut Med 2012;24(4):100-8.  https://doi.org/10.7730/JSCM.2012.24.4.100
  6. Han SS, Cho CK, Lee YW, Yoo HS. A Case Report on Extra nodal Marginal Zone B Cell of Mucosa-associated Lymphoid Tissue (MALT) Type Lymphoma Treated with Hangam-dan. Korean J Orient Int Med 2008;29(3):810-9. 
  7. Kim IS, Cheong MS, Oh HS, Lee YS. Case of a Diffuse Large B-Cell Lymphoma Patient Treated with Traditional Korean Medicine Treatment. Korean J Oriental Physiology & Pathology 2014;28(2):233-7. 
  8. Jung HS, Lee SH, Yoo HS, Kim KS. Clinical Practice Guidelines of Korean Medicine for Malignant Lymphoma. Korean J Orient Int Med 2016;37(3);453-66. 
  9. Ribrag V. Toward common response evaluation criteria for solid tumors and lymphomas: RECIL and RECIST?. Ann Oncol 2017;28(7):1409-11.  https://doi.org/10.1093/annonc/mdx209
  10. Younes A, Hilden P, Coiffier B, Hagenbeek A, Salles G, Wilson W, et al. International Working Group consensus response evaluation criteria in lymphoma (RECIL 2017). Ann oncol 2017;28(7):1436-47.  https://doi.org/10.1093/annonc/mdx097
  11. Yoshino T, Miyake K, Ichimura K, Mannami T, Ohara N, Hamazaki S, et al. Increased Incidence of Follicular Lymphoma in the Duodenum. Am J Surg Pathol 2000;24(5):688-93.  https://doi.org/10.1097/00000478-200005000-00007
  12. Kim HK, Cho IS, Lee HK, Choi YH, Cho SM, Moon HJ, et al. Transformation of CD5-Negative Follicular Lymphoma into CD5-Positive Diffuse Large B-Cell Lymphoma: A Case Report. Korean J Med 2012;83(2):263-7.  https://doi.org/10.3904/kjm.2012.83.2.263
  13. Relander T, Johnson NA, Farinha P, Connors JM, Sehn LH, Gascoyne RD. Prognostic factors in follicular lymphoma. J Clin Oncol 2010;28(17):2902-13.  https://doi.org/10.1200/JCO.2009.26.1693
  14. Kim DJ, Hahn JS, Jang JH, Lee ST, Min YH, Ko YW. Acute tumor lysis syndrome in patients with non-Hodgkin's lymphoma. Korean J Med 2000;58(3):306-9. 
  15. National Cancer Information Center, Available from: https://www.cancer.go.kr/lay1/program/S1T211C223/cancer/view.do?cancer_seq=114462&menu_seq=114480 
  16. Im CR, Kwon K, Sur YC, Bang SH, Kim SS, Sung S. A Case of Hepatic and Pulmonary Metastatic Colorectal Cancer Patient Treated by Traditional Korean Therapy and XELOX Chemotherapy. J Kor Trad Oncol 2012;17(1):17-25. 
  17. Jung HJ, Kim JD. The Role of Korean Medicine for Treatment and Management for Lung Cancer. J Kor Trad Oncol 2015;20(1):45-54.  https://doi.org/10.15432/JKTO.2015.20.1.045
  18. Kim RH, Moon BS, Yun JM. A Clinical Research Study of Moxibustion on Stroke Patients Korean J Orient Int Med 2011;32(3):361-70. 
  19. Ahn YM, Park HS, Kwon KR. Anti-Cancer and Anti-Oxidant Efficacies of Wild Ginseng and Cultivated Wild Ginseng of Korea and China. Journal of Korean Pharmacopuncture 2007;10(1):5-16. 
  20. Kim YJ, Lee JM, Lee E. Immunomodulatory Activity of Cultivated Wild Ginseng Pharmacopuncture. Journal of Meridian & Acupoint 2010;27(1):31-47. 
  21. Lee YH, Kim CW, Lee KH. A Case Report of Monitoring PSA Level Changes in Two Prostate Cancer Patients Treated with Mountain Ginseng Pharmacopuncture and Sweet Bee Venom along with Western Anticancer Therapy. Journal of Pharmacopuncture 2011;14(4);81-8.  https://doi.org/10.3831/KPI.2011.14.4.081
  22. Choi HJ, Park SJ, Choi YN, Kim SD, Kwag EB, Song SY. et al. Selective Immune Modulating Activities of Viscum album and Its Components; a Possibility of Therapeutics on Skin Rash Induced by EGFR Inhibitors. Integrative Cancer Therapies 2022;21:1-11. https://doi.org/10.1177/15347354221118332