Journal of Korean Neurosurgical Society

  • 제66권3호
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  • Pages.258-262
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  • 2023
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  • 2005-3711(pISSN)
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  • 1598-7876(eISSN)
대한신경외과학회 (The Korean Neurosurgical Society)
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Pharmacological Management of Germinal Matrix-Intraventricular Hemorrhage

  • Jaewoo Chung (Department of Neurosurgery, Dankook University College of Medicine) ;
  • Sang Koo Lee (Department of Neurosurgery, Dankook University College of Medicine) ;
  • Chun-Sung Cho (Department of Neurosurgery, Dankook University College of Medicine) ;
  • Young Jin Kim (Department of Neurosurgery, Dankook University College of Medicine) ;
  • Jung Ho Ko (Department of Neurosurgery, Dankook University College of Medicine) ;
  • Jung-Ho Yun (Department of Neurosurgery, Dankook University College of Medicine) ;
  • Jin-Shup So (Department of Neurosurgery, Dankook University Hospital) ;
  • In-Ho Jung (Department of Neurosurgery, Dankook University Hospital)
  • 투고 : 2022.12.05
  • 심사 : 2023.02.14
  • 발행 : 2023.05.01
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초록

Germinal matrix-intraventricular hemorrhage (GM-IVH) is among the devastating neurological complications with mortality and neurodevelopmental disability rates ranging from 14.7% to 44.7% in preterm infants. The medical techniques have improved throughout the years, as the morbidity-free survival rate of very-low-birth-weight infants has increased; however, the neonatal and long-term morbidity rates have not significantly improved. To this date, there is no strong evidence on pharmacological management on GM-IVH, due to the limitation of well-designed randomized controlled studies. However, recombinant human erythropoietin administration in preterm infants seems to be the only effective pharmacological management in limited situations. Hence, further high-quality collaborative research studies are warranted in the future to ensure better outcomes among preterm infants with GM-IVH.

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참고문헌

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