Korean Journal of Materials Research (한국재료학회지)

Materials Research Society of Korea (한국재료학회)
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Physical Properties, Antimicrobial Efficacy, and Biocompatibility of Denture Base Resins Coated with Natural Peony Extract

  • Myung-Jin Lee (Department of Dental Hygiene, Division of Health Science, Baekseok University) ;
  • Yu-Ri Choi (Department of Dental Hygiene, Hallym Polytechnic University) ;
  • Min-Kyung Kang (Department of Dental Hygiene, Hanseo University)
  • Received : 2023.01.25
  • Accepted : 2023.01.31
  • Published : 2023.02.27
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Abstract

When exposed to different types of bacteria in the oral cavity, denture based resins are prone to bacteria attachment. The purpose of this study was to investigate the physical, biological, and antimicrobial properties of denture base resins coated with Peony extract (200, 400, and 600 ㎍/mL). Specifically, the surface properties (microhardness, contact angle, and color change of the coated specimens), cell cytotoxicity (measured using MTT assay), and antimicrobial activity (against S. mutans (Streptococcus mutans) and C. albicans (Candida albicans) using a growth inhibition assay) were evaluated. The polyphenol content was measured using ultraviolet-visible (UV-vis) spectrometry. The experimental groups (specimens coated with Peony extract) and a control group (specimens coated without Peony extract) were statistically compared using a one-way analysis of variance and Tukey's post-hoc tests. No statistically significant differences in surface properties or cell cytotoxicity were observed, which demonstrated their biocompatibility. Conversely, a statistically significant difference in antimicrobial activity was observed between the experimental and control groups after 48 h. This confirms the antimicrobial activity of the denture base resin coated with Peony extract and demonstrates that it is a promising dental material for preventing stomatitis.

Keywords

Acknowledgement

This study was supported by National Research Foundation of Korea (NRF) grants funded by the Korean government (MSIT) (Nos. 2017R1C1B5076310 and 2020R1C1C1009703).

References

  1. Z. Li, J. Sun, J. Lan and Q. Qi, Gerodontology, 33, 209 (2016).
  2. A. A. M. N. Garcia, C. Y. C. Sugio, L. J. de Azevedo-Silva, A. C. G. Gomes, A. U. D. Batista, V. C. Porto, S. Soares and K. H. Neppelenbroek, Arch. Microbiol., 204, 75 (2021).
  3. M. J. Lee, M. J. Kim, S. H. Oh and J. S. Kwon, Materials (Basel), 13, 371 (2020). https://doi.org/10.3390/ma13020371
  4. S. M. Fouda, M. Gad, P. Ellakany, A. M. Al-Thobity, F. A. Al-Harbi, J. I. Virtanen and A. Raustia, J. Appl. Oral Sci., 27, e20180779 (2019).
  5. M. M. Gad, A. M. Al-Thobity, S. Y. Shahin, B. T. Alsaqer and A. A. Ali, Int. J. Nanomed., 12, 5409 (2017).
  6. Y. O. Latib, C. P. Owen and M. Patel, Int. J. Prosthodontics, 31, 436 (2018).
  7. S. O. Bajunaid, Polymers (Basel), 14, 908 (2022).
  8. M. J. Lee, J. S. Kwon, J. Y. Kim, J. H. Ryu, J. Y. Seo, S. Jang, K. M. Kim, C. J. Hwang and S. H. Choi, Dent. Mater., 35, 1331 (2019).
  9. C. Tsutsumi, K. Takakuda and N. Wakabayashi, J. Dent., 44, 37 (2016).
  10. M. M. Gad and S. M. Fouda, Dent. Med. Probl., 57, 95 (2020).
  11. M. J. Lee, U. Mangal, S. J. Kim, Y. P. Yoon, E. S. Ahn, E. S. Jang, J. S. Kwon and S. H. Choi, Polymers (Basel), 12, 1716 (2020). https://doi.org/10.3390/polym12081716
  12. S. An, J. L. Evans, S. Hamlet and R. M. Love, J. Prosthet. Dent., 126, 195 (2021).
  13. S. K. Park, Y. K. Lee, B. S. Lim and C. W. Kim, J. Oral Rehabil., 31, 717 (2004).
  14. M. J. Lee, Y. S. Shim, S. Y. An and M. K. Kang, Molecules, 26, 1440 (2021).
  15. M. J. Lee and M. K. Kang, Plants (Basel), 9, 988 (2020).
  16. W. J. Duan, J. Y. Yang, L. X. Chen, L. J. Zhang, Z. H. Jiang, X. D. Cai and X. Zhang, J. Nat. Prod., 72, 1579 (2009).
  17. S. Shakya, N. Danshiitsoodol, S. Sugimoto and M. Noda, Antioxidants (Basel), 10, 1071 (2021).
  18. J. Lu, Z. Huang, Y. Liu, H. Wang, M. Qiu, Y. Qu and W. Yuan, Molecules, 27, 506 (2021).
  19. X. X. Zhang, Q. Q. Shi, D. Ji, L. X. Ni and Y. L. Zhang, Food Res. Int., 97, 14 (2017).
  20. C. Li, H. Du, L. Wang, Q. Shu, Y. Zheng, Y. Xu, J. Zhang, J. Zhang, R. Yang and Y. Ge, J. Agric. Food Chem., 57, 8496 (2009).
  21. W. Zuo, D. Feng, A. Song, H. Gong and S. Zhu, J. Prosthet. Dent., 115, 103 (2017).
  22. N. Y. Jin, H. R. Lee, H. Lee and A. Pae, J. Adv. Prosthodontics, 1, 1 (2009).
  23. R. Chen, Z. Han, Z. Huang, J. Karki, C. Wang, Zhu and X. Zhang, Dent. Mater. J., 36, 693 (2017).
  24. J. W. Choi, M. J. Lee, S. H. Oh and K. M. Kim, Dent. Mater. J., 38, 33 (2019).
  25. F. Keyf and I. Etikan, Dent. Mater., 20, 244 (2004). https://doi.org/10.1016/S0109-5641(03)00099-X
  26. E. Azmy, M. R. Z. Al-Kholy, M. M. Gad, A. M. Al-Thobity, A. M. Emam and M. A. Helal, Int. J. Dent., 2021, 5861848 (2021).
  27. C. Koch, R. Burgers and S. Hahnel, Gerodontology, 30, 309 (2013).
  28. G. Paolone, S. Formiga, F. De Palma, L. Abbruzzese, L. Chirico, S. Scolavino, C. Goracci, G. Cantatore and A. Vichi, J. Esthetic Restor. Dent., 34, 865 (2022).
  29. M. J. Lee, M. J. Kim, J. S. Kwon, S. B. Lee and M. Kim, Materials (Basel), 10, 288 (2017).
  30. M. C. Goiato, E. Freitas, D. dos Santos, R. de Medeiros and M. Sonego, Adv. Clin. Exp. Med., 24, 679 (2015).
  31. J. J. Tzeng, T. S. Yang, W. F. Lee, H. Chen and H. M. Chang, Polymers (Basel), 13, 822 (2021).
  32. J. T. Huffines and J. A. Scoffield , Sci. Rep., 10, 19661 (2020).
  33. T. Y. Hosida, J. P. Pessan, T. P. Cavazana, C. Sampaio, D. R. Monteiro and A. C. Botazzo Delbem, Biofouling, 37, 939 (2021).
  34. M. S. Alves, L. R. O. Fugisaki, J. D. Dos Santos, L. Scorzoni, R. P. Medina and D. H. S. Silva, Med. Mycol., 59, 744 (2015).
  35. J. I. Lyu, J. Ryu, C. H. Jin, D. G. Kim, J. M. Kim, K. S. Seo, J. B. Kim, S. H. Kim, J. W. Ahn and S. Y. Kang, Molecules, 25, 4190 (2020).