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Evaluation of the physical properties and antibacterial effects on Candida albicans of denture base resin containing silver sulfadiazine

실버 설파다이아진이 첨가된 의치상용 레진의 Candida albicans에 대한 항균평가 및 물성 평가

  • Yu-Ri Choi (Department of Dental Hygiene, Hallym Polytechnic University) ;
  • Min-Kyung Kang (Department of Dental Hygiene, Hanseo University)
  • Received : 2023.10.08
  • Accepted : 2023.12.25
  • Published : 2023.12.30

Abstract

Objectives: The purpose of this study was to evaluate the physical properties and antibacterial activity of denture base resin with added silver sulfadiazine. Methods: Specimens were made from self-curing denture base resin and silver sulfadiazine as an inorganic antibacterial agent. For physical evaluation of the specimens, surface roughness, surface hardness, and contact angle were measured. Bacterial growth was assessed by optical densityat 600 nm (OD600) and colony forming units (CFU) measurements to confirm antibacterial activity. Results: There was no significant difference in surface roughness, surface hardness, and contact angle in the experimental group containing silver sulfadiazine compared to the control group. In contrast, the experimental group showed a significant decrease in antibacterial activity compared to the control group in terms of OD value. Analysis of CFU confirmed a significant decrease in colonies in the experimental group compared to the control group. Conclusions: Denture base resin containing silver sulfadiazine, an inorganic antibacterial agent, exhibited enhanced antibacterial activity without physical changes. In conclusion, the use of denture base resin containing inorganic antibacterial agents may be expected in the future.

Keywords

Acknowledgement

이 논문은 2023년 한서대학교 교내연구과제 지원사업의 지원을 받아 수행된 연구임.

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