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Evaluation of the Applicability of PET/CT Phantom as a 3D Printing Material

PET/CT 팬텀의 3D 프린팅 소재 적용 가능성 평가

  • Lee, Ju-young (Department of Radiological Technology, Songho University) ;
  • Kim, Ji-Hyeon (Department of Nuclear Medicine, Seoul Medical Center) ;
  • Park, Hoon-Hee (Department of Radiological Science, Shingu College)
  • Received : 2022.07.31
  • Accepted : 2022.09.23
  • Published : 2022.10.31

Abstract

The purpose of this study is to present objective information in applying 3D printing technology for PET/CT (Positron Emission Tomography/Computed Tomography) performance evaluation and use it as a basic research that can be applied to various purposes in the future. Phantoms were manufactured with step wedge of ABS(Acrylonitrile Butadiene Styrene) and ACR(Acrylic acid) material. The counts for each ROI(Region of Interest) were analyzed through image acquisition in PET/CT. And the variation rate of counts and CNR(Contrast Noise Ratio) was evaluated. In the counts analysis, the effect of thickness occurred. In addition, in the variation rate analysis, the thickness setting of steps wedge 4 to 5 levels should be considered first. These results minimize quantitative and qualitative changes in the phantom manufactured based on 3D printing, and enable more stable PET/CT performance evaluation. Based on 3D printing in PET/CT, various phantoms are expected to be produced in the future. If the characteristics of each material are considered and applied through the basic research such as this research, the result of the phantom manufactured through 3D printing can be more meaningful and will be used in a wide range.

Keywords

Acknowledgement

This study was carried out as a research fund support project of the Industry-Academic Cooperation Foundation of Shingu College.

References

  1. Christian C, Richard LW. Applications of positron emission tomography/computed tomography image fusion in clinical positron emission tomographyclinical use, interpretation methods, diagnostic improvements. Semin Nucl Med. 2003;33(3):228-37. https://doi.org/10.1053/snuc.2003.127312
  2. Oh JS. Nuclear Medicine Physics: Review of Advanced Technology. Progress in Medical Physics. 2020;31(3):81-98. https://doi.org/10.14316/pmp.2020.31.3.81
  3. Lee JS, Kim JH. Recent advances in hybrid molecular imaging systems. Semin Musculoskelet Radiol. 2014;18(02):103-22. https://doi.org/10.1055/s-0034-1371014
  4. Lee BI. Quality Assurance and Performance Evaluation of PET/CT. Nuclear Medicine and Molecular Imaging. 2008;42(2):137-44.
  5. Park HH, Lee JY, Kim JH. Evaluation of Scintillation Camera Applications of 3D Printing Phantom. Journal of Radiological Science and Technology. 2021;44(4):343-50. https://doi.org/10.17946/JRST.2021.44.4.343
  6. Park HH, Lee JY. Development and Evaluation of the Usefulness for Hoffman Brain Phantom Based on 3D Printing Technique. Journal of Radiological Science and Technology. 2019;42(6):441-6. https://doi.org/10.17946/JRST.2019.42.6.441
  7. Zein I, Hutmacher DW, Tan KC, Teoh SH. Fused Deposition Modeling of Novel Scaffold Architectures for Tissue Engineering Applications. Biomaterials. 2022;23(4):1169-85. https://doi.org/10.1016/S0142-9612(01)00232-0
  8. Yoo JJ, Lee IW. Regenerative Medicine. Koonja Publishing Inc.; 2010:293-508.
  9. Mannoor MS, Jiang Z, James T, Kong YL, Malatesta KA, et al. 3D Printed Bionic Ears. Nano Lett. 2013;13(6):2634-9. https://doi.org/10.1021/nl4007744
  10. Park SH, Park JH, Lee HJ, Lee NK. Current Status of Biomedical Applications using 3D Printing Technology. J Korean Soc Precis Eng. 2014;31(12): 1067-76. https://doi.org/10.7736/KSPE.2014.31.12.1067
  11. Lee SW, Kim TH, Hong DY, Ock JY, Kwon JY, Gwon ES, Kwon JH, et al. Review of Three-Dimensional Printing Technology for Medical Applications. J Korean Soc Radiol. 2019;80(2):213-25. https://doi.org/10.3348/jksr.2019.80.2.213
  12. Kim HC. A Study on the socio-economic impact of 3D Printing. Journal of Digital Convergence. 2015;13(7):23-31. https://doi.org/10.14400/JDC.2015.13.7.23
  13. Gear JI, Long C, Rushforth D, Chittenden SJ, Cumming C, Flux GD. Development of patient-specific molecular imaging phantoms using a 3D printer. Nuclear Medicine Physics. 2014;41(8):082502.
  14. Qiu J, Hou K, Dyer BA, Chen JC, Shi L, Sun Y, et al. Constructing Customized Multimodal Phantoms Through 3D Printing: A Preliminary Evaluation. Front Phys. 2021;9:605630. https://doi.org/10.3389/fphy.2021.605630
  15. Ivo R, Agustin R, Itziar VP, Jacobo CG, Thomas B Ignasi C. Performance Evaluation of the Vereos PET/CT System According to the NEMA NU2-2012 Standard. J Nucl Med. 2019;60(4):561-7. https://doi.org/10.2967/jnumed.118.215541