과제정보
본 성과물은 2022년도 정부(과학기술정보통신부)의 재원으로 한국연구재단(No. 2018R1A5A2025272)과 주영엔에스(주)의 지원에 의해 수행되었습니다.
참고문헌
- Min GY, Park JM, Joo IH, Kim DH. Inhibition effect of Caragana sinica root extracts on Osteoarthritis through MAPKs, NF-κB signaling pathway. Int J Med Sci. 2021;18(4):861-872. https://doi.org/10.7150/ijms.52330
- Lan H, Hong W, Qian D, Peng F, Li H, Liang C, Du M, Gu J, Mai J, Bai B, Peng G. Quercetin modulates the gut microbiota as well as the metabolome in a rat model of osteoarthritis. Bioengineered. 2021;12(1):6240-6250. https://doi.org/10.1080/21655979.2021.1969194
- Robinson WH, Lepus CM, Wang Q, Raghu H, Mao R, Lindstrom TM, Sokolove J. Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis. Nat Rev Rheumatol. 2016;12(10):580-592. https://doi.org/10.1038/nrrheum.2016.136
- Grynpas MD, Alpert B, Katz I, Lieberman I, Pritzker KP. Subchondral bone in osteoarthritis. Calcif Tissue Int. 1991;49(1):20-26. https://doi.org/10.1007/BF02555898
- Kim MJ, Lee JA, Shin MR, Park HJ, Roh SS. Improvement Effect of Corni Fructus 30% Ethanol Extract by MIA-Induced Osteoarthritis Animal Model. Kor. J. Herbol. 2020;35(1):35-44.
- Pakr WT, Jeong SH, Seo IB, Kim SJ. GCP Treatment on the Expression of NOS, C-fos, Serotonin and Substance-P in central nerve system of monosodiumiodoacetate-induced osteoarthritic Pain Model. J Kor Oriental Physiology & Pathology. 2007;21(6):1483-1490.
- Kim JS, Lee AY, Moon BC, Kim HS, Kim WJ, Kim C, Choi GY, Kim SH, Chun JM. Effects of aqueous extract from Taxillus chinensis on monosodium iodoacetate-induced osteoarthritis in rats. Kor. J. Herbol. 2018;33(5):81-88.
- Lee SI, Kwon KB, Han JH, Ryu DG. Effects of Olibanum Extracts on Vascular Cell Adhesion Molecules Expression. Korean J. Oriental Physiology & Patholog. 2011;25(3):445-450.
- Cho SA, Ryu EM. Effect of Boswellia on the Expression of Hair Cycle-related Genes in Skin of DNCB-induced Atopic Dermatitis Mice. J Invest Cosmetol. 2021;17(1):25-30
- Nam DE, Kim OK, Shim TJ, Kim JH, Lee JM. Effect of Boswellia serrata Extracts on Degenerative Osteoarthritis in vitro and in vivo Models. J Korean Soc Food Sci Nutr. 2014;43(5):631-640. https://doi.org/10.3746/jkfn.2014.43.5.631
- Siddiqui MZ. Boswellia serrata, a potential antiinflammatory agent: an overview. Indian J Pharm Sci. 2011;73(3):255-261.
- Buchelle B, Simmet T. Analysis of 12 different pentacyclic triterpenic acids from frankincense in human plasma by high-performance liquid chromatography and photodiode array detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2003;795(2):355-362. https://doi.org/10.1016/S1570-0232(03)00555-5
- Efferth T, Oesch F. Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities. Semin Cancer Biol. 2022;80:39-57. https://doi.org/10.1016/j.semcancer.2020.01.015
- Schweizer S, von Brocke AF, Boden SE, Bayer E, Ammon HP, Safayhi H. Workup-dependent formation of 5-lipoxygenase inhibitory boswellic acid analogues. J Nat Prod. 2000;63(8):1058-1061. https://doi.org/10.1021/np000069k
- Kim HJ, Shin EC, Yoo NJ, Park JH, Kim SK, Kang ES, Jahng JS. Apoptosis of Chondro cytes and Its Regulation in Pathogenesis of Osteoarthritis. J Korean Rheumatic Diseases. 2001;8(2):104-117.
- Kim EN, Roh SS, Jeong GS. Inhibitory Effect of Sparassis crispa (Wulf.) Extract on Monosodium Iodoacetate Induced Osteoarthritis. J Korean Pharmacogn. 2018;49(3):262-269.
- de David C, Rodrigues G, Bona S, Meurer L, Gonzalez-Gallego J, Tunon MJ, Marroni NP. Role of quercetin in preventing thioacetamide-induced liver injury in rats. Toxicol Pathol. 2011;39(6):949-957. https://doi.org/10.1177/0192623311418680
- Kwon JH, Han MS, Lee BM, Lee YM. Effect of Angelica gigas extract powder on progress of osteoarthritis induced by monosodium iodoacetate in rat. ANALYTICAL SCIENCE & TECHNOLOGY. 2015;28(1):72-77. https://doi.org/10.5806/AST.2015.28.1.72
- Saberi Hosnijeh F, Siebuhr AS, Uitterlinden AG, Oei EH, Hofman A, Karsdal MA, Bierma-Zeinstra SM, Bay-Jensen AC, van Meurs JB. Association between biomarkers of tissue inflammation and progression of osteoarthritis: Evidence from the Rotterdam study cohort. Arthritis Res Ther. 2016;18:81-90. https://doi.org/10.1186/s13075-016-0976-3
- Vilim V, Olejarova M, Machacek S, Gatterova J, Kraus VB, Pavelka K. Serum levels of cartilage oligomeric matrix protein (COMP) correlate with radiographic progression of knee osteo- arthritis. Osteoarthritis Cartilage. 2002;10(9):707-713. https://doi.org/10.1053/joca.2002.0819
- Sailer ER, Schweizer S, Boden SE, Ammon HP, Safayhi H. Characterization of an acetyl-11-keto-beta-boswellic acid and arachidonate-binding regulatory site of 5-lipoxygenase using photoaffinity labeling. Eur J Biochem. 1998;256(2):364-368. https://doi.org/10.1046/j.1432-1327.1998.2560364.x
- Ghosh J, Myers CE. Arachidonic acid stimulates prostate cancer cell growth: critical role of 5-lipoxygenase. Biochem Biophys Res Commun. 1997;235(2):418-423. https://doi.org/10.1006/bbrc.1997.6799
- Wang B, Wu L, Chen J, Dong L, Chen C, Wen Z, Hu J, Fleming L, Wang DW. Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets. Signal Transduct Target Ther. 2021;6(1):94-124. https://doi.org/10.1038/s41392-020-00443-w
- Evans JF, Ferguson AD, Mosley RT, Hutchinson JH. What's all the FLAP about?: 5-lipoxygenase-activating protein inhibitors for inflammatory diseases. Trends Pharmacol Sci. 2008;29(2):72-78. https://doi.org/10.1016/j.tips.2007.11.006
- Min KR, Shin JM, Chang YS, Kim YS. The Activity of 5-Lipoxygenase and the Inhibitor of Leukotriene B4 Biosynthesis. Yakhak Hoeji. 1989;33(6):319-323.
- Enderes J, Mallesh S, Stein K, Wagner M, Lysson M, Schneiker B, Kalff JC, Wehner S. Treatment with the 5-Lipoxygenase Antagonist Zileuton Protects Mice from Postoperative Ileus. Eur Surg Res. 2022;2022:1792894.
- Lopes DEM, Jabr CL, Dejani NN, Saraiva AC, de Aquino SG, Medeiros AI, Rossa Junior C. Inhibition of 5-lipoxygenase attenuates inflammation and bone resorption in lipopolysaccharide-induced periodontal disease. J Periodontol. 2018;89(2):235-345.
- Ahmed MAE, Ahmed AAE, El Morsy EM. Acetyl-11-keto-β-boswellic acid prevents testicular torsion/detorsion injury in rats by modulating 5-LOX/LTB4 and p38-MAPK/JNK/Bax/Caspase-3 pathways. Life Sci. 2020;260:118472. https://doi.org/10.1016/j.lfs.2020.118472
- Gilbert NC, Gerstmeier J, Schexnaydre EE, Borner F, Garscha U, Neau DB, Werz O, Newcomer ME. Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products. Nat Chem Biol. 2020;16(7):783-790. https://doi.org/10.1038/s41589-020-0544-7
- Werz O, Burkert E, Samuelsson B, Radmark O, Steinhilber D. Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes. Blood. 2002;99(3):1044-1052. https://doi.org/10.1182/blood.V99.3.1044
- Kim MJ, Park HJ, Kim KJ, Lee JA, Shin MR, Roh SS. Protective Effect of Dioscoreae Rhizoma Extracts in MIA-induced Rat. Kor. J. Herbol. 2019;34(4):27-35.
- Nelson AR, Fingleton B, Rothenberg ML, Matrisian LM. Matrix metalloproteinases: biolobic activity ans clinical implication. J Clin Oncol. 2000;18:1135-1149. https://doi.org/10.1200/JCO.2000.18.5.1135
- Lee HJ, Park JO, Oh MS. Anti-inflammation and antioxidation effects of gamikyejakjimo-tang herbal acupuncture on pathologic factor and MIA-induced osteoarthritis rat. J Korean Med Rehab. 2015;25(4):1-20.