Acknowledgement
This study was supported by the statutory fund of the Department of Biotechnology, Poland. Also, partially by grant No.: UMO-2014/13/D/NZ7/00292, assigned by the National Science Centre, Poland, to K. Stachowicz and by the statutory fund of the Maj Institute of Pharmacology, Polish Academy of Sciences in Krakow (Protocol No 178/2017).
References
- Wang SM, Han C, Bahk WM, Lee SJ, Patkar AA, Masand PS, Pae CU (2018) Addressing the side effects of contemporary antidepressant drugs: a comprehensive review. Chonnam Med J 54:101-112. https://doi.org/10.4068//cmj.2018.54.2.101
- Casilla-Lennon MM, Meltzer-Brody S, Steiner AZ (2016) The effect of antidepressants on fertility. Am J Obserics Gynecol 215:314.e311-315. https://doi.org/10.1016/j.fertnstert.2014.12.023
- Hendrick V, Gitlin M, Althshuler L, Korenman S (2000) Antidepressant medications, mood and male fertility. Psychoneuroendocrinology 25:37-51. https://doi.org/10.1016//S0306-4530(99)00038-4
- Tanrikut C, Schlegel PN (2007) Antidepressant-associated changes in semen parameters. Urology 69:185-187. https://doi.org//10.1016/j.urology.2006.10.034
- Hendrick V, Gitlin M, Altshuler L, Korenman S (2000) Antidepressant medications, mood and male fertility. Psychoneuroendocrinology 25:37-51. https://doi.org/10.1016//s0306-4530(99)00038-4
- Nalbandian A, Dettin L, Dym M, Ravindranath N (2003) Expression of vascular endothelial growth factor receptors during male germ cell differentiation in the mouse. Biol Reprod 69:985-994. https://doi.org/10.1095//biolreprod.102.013581
- Agrawal R, Jacobs H, Payne N, Conway G (2002) Concentration of vascular endothelial growth factor released by cultured human luteinized granulosa cells is higher in women with polycystic ovaries than in women with normal ovaries. Fertil Steril 78:1164-1169. https://doi.org/10.1016//S0015-0282(02) 04242-5
- Griffeth RJ, Bianda V, Nef S (2014) The emerging role of insulinlike growth factors in testis development and function. Basic Clin Androl 24:12. https://doi.org/10.1186//2051-4190-24-12
- Ayson FG, de Jesus EG, Moriyama S, Hyodo S, Funkenstein B, Gertler A, Kawauchi H (2002) Differential expression of insulin-like growth factor I and II mRNAs during embryogenesis and early larval development in rabbitfish, Siganus guttatus. Gen Comp Endocrinol 126:165-174. https://doi.org/10.1006/gcen.2002.7788
- Gonzalez CR, Matzkin ME, Frungieri MB, Terradas C, Ponzio R, Puigdomenech E, Levalle O, Calandra RS, Gonzalez-Calvar SI (2010) Expression of the TGF-beta1 system in human testicular pathologies. Reprod Biol Endocrinol 8:148. https://doi.org//10.1186//1477-7827-8-148
- Maranesi M, Zerani M, Leonardi L, Pistilli A, Arruda-Alencar J, Stabile AM, Rende M, Castellini C, Petrucci L, Parillo F, Moura A, Boiti C (2015) Gene expression and localization of NGF and its cognate receptors NTRK1 and NGFR in the sex organs of male rabbits. Reprod Domest Anim 50:918-925. https://doi.org/10.1111//rda.12609
- Shiraishi K, Matsuyama H (2012) Local expression of epidermal growth factor-like growth factors in human testis and its role in spermatogenesis. J Androl 33:66-73. https://doi.org/10.2164//jandrol.110.011981
- Li SA, Watanabe M, Yamada H, Nagai A, Kinuta M, Takei K (2004) Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice. Cell Struct Funct 29:91-99. https://doi.org/10.1247//csf.29.91
- Lim K, Groen A, Molostvov G, Lu T, Lilley KS, Snead D, James S, Wilkinson IB, Ting S, Hsiao LL, Hiemstra TF, Zehnder D (2015) alpha-Klotho Expression in Human Tissues. J Clin Endocrinol Metab 100:E1308-E1318. https://doi.org/10.1210/jc.2015-1800
- Wang Y, Sun Z (2009) Current understanding of klotho. Ageing Res Rev 8:43-51. https://doi.org/10.1016/j. arr. 2008. 10. 002
- Painsipp E, Kofer MJ, Sinner F, Holzer P (2011) Prolonged depression-like behavior caused by immune challenge: influence of mouse strain and social environment. PLoS ONE 6:e20719. https://doi.org/10.1371//journal.pone.0020719
- Martin SA, Dantzer R, Kelley KW, Woods JA (2014) Voluntary wheel running does not affect lipopolysaccharide-induced depressive-like behavior in young adult and aged mice. Neuro-ImmunoModulation 21:52-63. https://doi.org/10.1159//000356144
- Stachowicz K (2019) Behavioral consequences of co-administration of MTEP and the COX-2 inhibitor NS398 in mice. Part 1. Behav Brain Res 370:111961. https://doi.org/10.1016/j.bbr.2019.111961
- Stachowicz K, Bobula B, Tokarski K (2020) NS398, a cyclooxygenase-2 inhibitor, reverses memory performance disrupted by imipramine in C57Bl/6J mice. Brain Res 1734:146741. https://doi.org//10.1016/j.brainres.2020.146741
- Schmidt JA, de Avila JM, McLean DJ (2007) Analysis of gene expression in bovine testis tissue prior to ectopic testis tissue xenografting and during the grafting period. Biol Reprod 76:1071-1080. https://doi.org/10.1095//biolreprod.106.058222
- Evans-Hoeker EA, Eisenberg E, Diamond MP, Legro RS, Alvero R, Coutifaris C, Casson PR, Christman GM, Hansen KR, Zhang H, Santoro N, Steiner AZ (2018) Major depression, antidepressant use, and male and female fertility. Fertil Steril 109:879-887. https://doi.org/10.1016/j.fertnstert.2018.01.029
- Palaniyappan L, Insole L, Ferrier N (2009) Combining antidepressants: a review of evidence. Adv Psychiatr Treat 15:90-99. https://doi.org//10.1192//apt.bp.107.004820
- Lupu F, Terwilliger JD, Lee K, Segre GV, Efstratiadis A (2001) Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth. Dev Biol 229:141-162. https://doi.org/10.1006//dbio.2000.9975
- Yan YC, Sun YP, Zhang ML (1998) Testis epidermal growth factor and spermatogenesis. Arch Androl 40:133-146. https://doi.org//10.3109//01485019808987936
- Pomierny-Chamiolo L, Poleszak E, Pilc A, Nowak G (2010) NMDA but not AMPA glutamatergic receptors are involved in the antidepressant-like activity of MTEP during the forced swim test in mice. Poland Pharmacol Rep 62:1186-1190. https://doi.org//10.1016//S1734-1140(10)70381-9
- Palucha-Moniewiera A, Wieronska JM, Branski P, Burnat G, Chruscicka B, Pilc A (2013) Is the mGlu5 receptor a possible target for new antidepressant drugs? Pharmacol Rep 65:1506-1511. https://doi.org/10.1016//s1734-1140(13)71511-1
- Marciniak M, Chruscicka B, Lech T, Burnat G, Pilc A (2016) Expression of group III metabotropic glutamate receptors in the reproductive system of male mice. Reprod Fertil Dev 28:369-374. https://doi.org/10.1071//RD14132
- Wang X, Liang Y, Wang J, Wang M (2013) Effect of NS-398, a cyclooxygenase-2 selective inhibitor, on the cytotoxicity of cytotoxic T lymphocytes to ovarian carcinoma cells. Tumour Biol 34:1517-1522. https://doi.org/10.1007//s13277-013-0677-3
- Muller N, Schwarz MJ (2008) COX-2 inhibition in schizophrenia and major depression. Curr Pharm Des 14:1452-1465. https://doi.org//10.2174//138161208784480243
- Romanelli F, Valenca M, Conte D, Isidori A, Negro-Vilar A (1995) Arachidonic acid and its metabolites effects on testosterone production by rat Leydig cells. J Endocrinol Invest 18:186-193. https://doi.org/10.1007//BF03347801
- Moraga PF, Llanos MN, Ronco AM (1997) Arachidonic acid release from rat Leydig cells depends on the presence of luteinizing hormone/human chorionic gonadotrophin receptors. J Endocrinol 154:201-209. https://doi.org/10.1677//joe.0.1540201
- Wang X, Walsh LP, Reinhart AJ, Stocco DM (2000) The role of arachidonic acid in steroidogenesis and steroidogenic acute regulatory (StAR) gene and protein expression. J Biol Chem 275:20204-20209. https://doi.org/10.1074//jbc.M003113200
- Wang X, Dyson MT, Jo Y, Stocco DM (2003) Inhibition of cyclooxygenase-2 activity enhances steroidogenesis and steroidogenic acute regulatory gene expression in MA-10 mouse Leydig cells. Endocrinology 144:3368-3375. https://doi.org/10.1210//en.2002-0081
- Marks DM, Shah MJ, Patkar AA, Masand PS, Park GY, Pae CU (2009) Serotonin-norepinephrine reuptake inhibitors for pain control: premise and promise. Curr Neuropharmacol 7:331-336. https://doi.org/10.2174//157015909790031201
- Haigh JJ (2008) Role of VEGF in organogenesis. Organogenesis 4:247-256. https://doi.org/10.4161//org.4.4.7415
- Brown LF, Yeo KT, Berse B, Morgentaler A, Dvorak HF, Rosen S (1995) Vascular permeability factor (vascular endothelial growth factor) is strongly expressed in the normal male genital tract and is present in substantial quantities in semen. J Urol 154:576-579. https://doi.org/10.1016//S0022-5347(01)67114-3
- Olofsson B, Korpelainen E, Pepper MS, Mandriota SJ, Aase K, Kumar V, Gunji Y, Jeltsch MM, Shibuya M, Alitalo K, Eriksson U (1998) Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells. Proc Natl Acad Sci USA 95:11709-11714. https://doi.org/10.1073//pnas.95.20.11709
- Luo H, Kimura K, Aoki M, Hirako M (2002) Vascular endothelial growth factor (VEGF) promotes the early development of bovine embryo in the presence of cumulus cells. J Vet Med Sci 64:967-971. https://doi.org/10.1292//jvms.64.967
- Obermair A, Obruca A, Pohl M, Kaider A, Vales A, Leodolter S, Wojta J, Feichtinger W (1999) Vascular endothelial growth factor and its receptors in male fertility. Fertil Steril 72:269-275. https://doi.org//10.1016//s0015-0282(99)00234-4
- Korpelainen EI, Karkkainen MJ, Tenhunen A, Lakso M, Rauvala H, Vierula M, Parvinen M, Alitalo K (1998) Overexpression of VEGF in testis and epididymis causes infertility in transgenic mice: evidence for nonendothelial targets for VEGF. J Cell Biol 143:1705-1712. https://doi.org/10.1083//jcb.143.6.1705
- Tabecka-Lonczynska A, Mytych J, Solek P, Kowalewski MP, Koziorowski M (2019) Seasonal expression of insulin-like growth factor 1 (IGF-1), its receptor IGF-1R and klotho in testis and epididymis of the European bison (Bison bonasus, Linnaeus 1758). Theriogenology 126:199-205. https://doi.org/10.1016/j.theriogenology.2018.12.016
- Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF (1983) Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219:983-985. https://doi.org/10.1126//science.6823562
- Reinecke M, Collet C (1998) The phylogeny of the insulin-like growth factors. Int Rev Cytol 183:1-94. https://doi.org/10.1016/S0074-7696(08)60142-4
- Perrot V, Moiseeva EB, Gozes Y, Chan SJ, Funkenstein B (2000) Insulin-like growth factor receptors and their ligands in gonads of a hermaphroditic species, the gilthead seabream (Sparus aurata): expression and cellular localization. Biol Reprod 63:229-241. https://doi.org/10.1095//biolreprod63.1.229
- Nakamura M, Kobayashi T, Chang XT, Nagahama Y (1998) Gonadal sex differentiation in teleost fish. J Exp Zool 281:362-372. https://doi.org/10.1002//(SICI)1097-010X(19980 801)281:5<362::AID-JEZ3>3.0.CO;2-M
- Tse MC, Vong QP, Cheng CH, Chan KM (2002) PCR-cloning and gene expression studies in common carp (Cyprinus carpio) insulin-like growth factor-II. Biochim Biophys Acta 1575:63-74. https://doi.org/10.1016//s0167-4781(02)00244-0
- Vinas J, Piferrer F (2008) Stage-specific gene expression during fish spermatogenesis as determined by laser-capture microdissection and quantitative-PCR in sea bass (Dicentrarchus labrax) gonads. Biol Reprod 79:738-747. https://doi.org/10.1095//biolreprod.108.069708
- Greene MW, Chen TT (1997) Temporal expression pattern of insulin-like growth factor mRNA during embryonic development in a teleost, rainbow trout (Onchorynchus mykiss). Mol Mar Biol Biotechnol 6:144-151 (PMID: 9200841)
- Radhakrishnan B, Oke BO, Papadopoulos V, DiAugustine RP, Suarez-Quian CA (1992) Characterization of epidermal growth factor in mouse testis. Endocrinology 131:3091-3099. https://doi.org//10.1210//endo.131.6.1446643
- Kassab M, Abd-Elmaksoud A, Ali MA (2007) Localization of the epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) in the bovine testis. J Mol Histol 38:207-214. https://doi.org/10.1007//s10735-007-9089-2
- He J, Dong C, You R, Zhu Z, Lv L, Smith GW (2009) Localization of epidermal growth factor (EGF) and its receptor (EGFR) during postnatal testis development in the alpaca (Lama pacos). Anim Reprod Sci 116:155-161. https://doi.org/10.1016/j.anireprosci.2009.01.002
- Pan Y, Cui Y, Yu S, Zhang Q, Fan J, Abdul Rasheed B, Yang K (2014) The expression of epidermal growth factor (EGF) and its receptor (EGFR) during post-natal testes development in the yak. Reprod Domest Anim 49:970-976. https://doi.org/10.1111//rda.12416
- Wong RW, Kwan RW, Mak PH, Mak KK, Sham MH, Chan SY (2000) Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice. J Biol Chem 275:18297-18301. https://doi.org/10.1074//jbc.M001965200
- Leone F, Lofaro D, Gigliotti P, Perri A, Vizza D, Toteda G, Lupinacci S, Armentano F, Papalia T, Bonofiglio R (2014) Soluble Klotho levels in adult renal transplant recipients are modulated by recombinant human erythropoietin. J Nephrol 27:577-585. https://doi.org//10.1007//s40620-014-0089-5
- Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, Ohyama Y, Kurabayashi M, Kaname T, Kume E, Iwasaki H, Iida A, Shiraki-Iida T, Nishikawa S, Nagai R, Nabeshima YI (1997) Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 390:45-51. https://doi.org/10.1038/36285
- Koh N, Fujimori T, Nishiguchi S, Tamori A, Shiomi S, Nakatani T, Sugimura K, Kishimoto T, Kinoshita S, Kuroki T, Nabeshima Y (2001) Severely reduced production of klotho in human chronic renal failure kidney. Biochem Biophys Res Commun 280:1015-1020. https://doi.org/10.1006//bbrc.2000.4226
- Imai M, Ishikawa K, Matsukawa N, Kida I, Ohta J, Ikushima M, Chihara Y, Rui X, Rakugi H, Ogihara T (2004) Klotho protein activates the PKC pathway in the kidney and testis and suppresses 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression. Endocrine 25:229-234. https://doi.org/10.1385//ENDO:25:3:229
- Chang WY, Kulp SK, Sugimoto Y, Canatan H, Shidaifat F, Inpanbutr N, Lin YC (1996) Detection of keratinocyte growth factor (KGF) messenger ribonucleic acid and immunolocalization of KGF in the canine testis. Endocrine 5:247-255. https://doi.org/10.1007//BF02739057
- Sawada J, Itakura A, Tanaka A, Furusaka T, Matsuda H (2000) Nerve growth factor functions as a chemoattractant for mast cells through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways. Blood 95:2052-2058. https://doi.org/10.1182//blood.V95.6.2052
- Skaper SD (2017) Nerve growth factor: a neuroimmune crosstalk mediator for all seasons. Immunology 151:1-15. https://doi.org/10.1111//imm.12717
- Cupp AS, Kim GH, Skinner MK (2000) Expression and action of neurotropin-3 and nerve growth factor in embryonic and early postnatal rat testis development. Biol Reprod 63:1617-1628. https://doi.org/10.1095//biolreprod63.6.1617
- Wang H, Dong Y, Chen W, Hei J, Dong C (2011) Expression and localization of nerve growth factor (NGF) in the testis of alpaca (llama pacos). Folia Histochem Cytobiol 49:55-61. https://doi.org//10.5603//FHC.2011.0009
- Lui WY, Lee WM, Cheng CY (2003) TGF-betas: their role in testicular function and Sertoli cell tight junction dynamics. Int J Androl 26:147-160. https://doi.org/10.1046/j.1365-2605.2003.00410.x