Journal of Oral Medicine and Pain

Korean Academy of Orofacial Pain and Oral Medicine (대한안면통증구강내과학회)
권호 표지
DOI QR코드

DOI QR Code

Necrotizing Sialometaplasia: A Diagnostic Puzzle for Clinicians

  • Jeong, Bo-Young (Department of Oral medicine, Seoul National University Dental Hospital) ;
  • Park, Hee-Kyung (Department of Oral medicine, Seoul National University Dental Hospital)
  • Received : 2022.05.26
  • Accepted : 2022.06.09
  • Published : 2022.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Necrotizing sialometaplasia is a rare, benign, self-limiting inflammatory process, with most cases occurring in the palatal region. Although the pathophysiology of this condition remains unknown, it has generally been considered an ischemic reaction involving the minor salivary glands. Due to its clinical and histologic similarities to malignant salivary gland tumor, diagnostic biopsy is required. Careful monitoring is also recommended, and clinicians should provide sufficient information for pathologists to ensure the histologic diagnosis.

Keywords

References

  1. Neville BW, Damm DD, Allen CM, Chi AC. Oral and maxillofacial pathology. 4th ed. St Louis: Elsevier; 2016. pp. 439-440.
  2. Abrams AM, Melrose RJ, Howell FV. Necrotizing sialometaplasia. A disease simulating malignancy. Cancer 1973;32:130-135. https://doi.org/10.1002/1097-0142(197307)32:1<130::AID-CNCR2820320118>3.0.CO;2-8
  3. Senapati S, Samal SC, Kumar R, Patra S. Necrotizing sialometaplasia: manifestation of a localized unclassified vasculitis. Indian J Pathol Microbiol 2016;59:232-234. https://doi.org/10.4103/0377-4929.182018
  4. Standish SM, Shafer WG. Serial histologic effects of rat submaxillary and sublingual salivary gland duct and blood vessel ligation. J Dent Res 1957;36:866-879. https://doi.org/10.1177/00220345570360060801
  5. Shigematsu H, Shigematsu Y, Noguchi Y, Fujita K. Experimental study on necrotizing sialometaplasia of the palate in rats. Role of local anesthetic injections. Int J Oral Maxillofac Surg 1996;25:239-241. https://doi.org/10.1016/S0901-5027(96)80038-5
  6. Salvado F, Nobre MA, Gomes J, Maia P. Necrotizing sialometaplasia and bulimia: a case report. Medicina (Kaunas) 2020;56:188. https://doi.org/10.3390/medicina56040188
  7. Gilowski L, Wiench R, Polakiewicz-Gilowska A, Dwornicka K. Necrotizing sialometaplasia of the palatal mucosa in patient with history of anorexia: review and case report. Am J Otolaryngol 2014;35:400-401. https://doi.org/10.1016/j.amjoto.2014.03.001
  8. Maisel RH, Johnston WH, Anderson HA, Cantrell RW. Necrotizing sialometaplasia involving the nasal cavity. Laryngoscope 1977;87:429-434. https://doi.org/10.1288/00005537-197703000-00016
  9. Kandula S, Manjunatha BS, Tayee P, Astekar M. Bilateral necrotising sialometaplasia. BMJ Case Rep 2016;2016:bcr2015211348.
  10. Brannon RB, Fowler CB, Hartman KS. Necrotizing sialometaplasia. A clinicopathologic study of sixty-nine cases and review of the literature. Oral Surg Oral Med Oral Pathol 1991;72:317-325. https://doi.org/10.1016/0030-4220(91)90225-2
  11. Anneroth G, Hansen LS. Necrotizing sialometaplasia. The relationship of its pathogenesis to its clinical characteristics. Int J Oral Surg 1982;11:283-291. https://doi.org/10.1016/s0300-9785(82)80027-6
  12. Dadfarnia T, Mohammed BS, Eltorky MA. Significance of Ki-67 and p53 immunoexpression in the differential diagnosis of oral necrotizing sialometaplasia and squamous cell carcinoma. Ann Diagn Pathol 2012;16:171-176. https://doi.org/10.1016/j.anndiagpath.2011.08.011
  13. Mesa ML, Gertler RS, Schneider LC. Necrotizing sialometaplasia: frequency of histologic misdiagnosis. Oral Surg Oral Med Oral Pathol 1984;57:71-73. https://doi.org/10.1016/0030-4220(84)90264-0
  14. Lee DJ, Ahn HK, Koh ES, Rho YS, Chu HR. Necrotizing sialometaplasia accompanied by adenoid cystic carcinoma on the soft palate. Clin Exp Otorhinolaryngol 2009;2:48-51. https://doi.org/10.3342/ceo.2009.2.1.48
  15. Zhurakivska K, Maiorano E, Nocini R, et al. Necrotizing sialometaplasia can hide the presence of salivary gland tumors: a case series. Oral Dis 2019;25:1084-1090. https://doi.org/10.1111/odi.13066
  16. Yagihara K, Ishii J, Katsurano M, Tsuchida E, Okamura T, Ishikawa A. A case of necrotizing sialometaplasia clinically mimicking a malignant tumor of the palate. Oral Sci Int 2018;15:73-77. https://doi.org/10.1016/S1348-8643(18)30002-8