Necrotizing Sialometaplasia: A Diagnostic Puzzle for Clinicians

  • Jeong, Bo-Young (Department of Oral medicine, Seoul National University Dental Hospital) ;
  • Park, Hee-Kyung (Department of Oral medicine, Seoul National University Dental Hospital)
  • Received : 2022.05.26
  • Accepted : 2022.06.09
  • Published : 2022.06.30


Necrotizing sialometaplasia is a rare, benign, self-limiting inflammatory process, with most cases occurring in the palatal region. Although the pathophysiology of this condition remains unknown, it has generally been considered an ischemic reaction involving the minor salivary glands. Due to its clinical and histologic similarities to malignant salivary gland tumor, diagnostic biopsy is required. Careful monitoring is also recommended, and clinicians should provide sufficient information for pathologists to ensure the histologic diagnosis.



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