Natural Product Sciences

  • 제28권2호
  • /
  • Pages.62-67
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  • 2022
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  • 1226-3907(pISSN)
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  • 2288-9027(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
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Chemical Profile and Cytotoxicity Activity of Stem-bark of Anacardium occidentale

  • Shehu, Abdullahi (Department of Chemistry, Faculty of Science, Federal University Lokoja) ;
  • Ponnapalli, Mangala Gowri (Centre for Natural Products and Traditional Knowledge, Indian Institute of Chemical Technology) ;
  • Mahboob, Mohd (Toxicology Unit, Biology Division, Indian Institute of Chemical Technology) ;
  • Prabhakar, Pitta Venkata (Toxicology Unit, Biology Division, Indian Institute of Chemical Technology) ;
  • Olatunji, Gabriel Ademola (Department of Industrial Chemistry, Faculty of Physical Sciences, University of Ilorin)
  • 투고 : 2022.05.23
  • 심사 : 2022.06.15
  • 발행 : 2022.06.30
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초록

Column chromatographic fractionation of the methanol and ethyl acetate extracts of the stem-bark of Anacardium occidentale led to the isolation of five compounds (1-5). Their structures were determined by spectroscopic means by comparing spectral data to be β-sitosterol (1), 2,4-dihydroxy acetophenone (2), 1-monolinolein (3), ethyl oleate (4) and β-sitosterol-3-O-β-D-glucopyranoside (5). These compounds were evaluated for cytotoxicity against human cancer cell lines: A549, SCOV3 and rat normal cell line NRK49f. Compounds 2-5 were for the first time isolated from A. occidentale.

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과제정보

The authors acknowledge Tertiary Education Fund (TETFUND), Federal University Lokoja, Nigeria; The World Academic of Science (TWAS), Italy and the council for Scientific and Industrial Research (CSIR)/Indian Institute of Chemical Technology (IICT), India for constant support and encouragement.

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