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Effect of COVID-19 vaccinations on deaths of the COVID-19 cases in some elderly long-term care facilities, Gwangju

광주광역시 요양시설 코로나19 집단 발생 사례에서 코로나19 백신 접종에 의한 사망 예방 효과

  • Ryu, So Yeon (Department of Preventive Medicine, College of Medicine, Chosun University) ;
  • Cho, Jun Hwi (Gwangju Center for Infectious Diseases Control and Prevention) ;
  • Lee, Ran (Gwangju Center for Infectious Diseases Control and Prevention) ;
  • Park, So Yeong (Gwangju Center for Infectious Diseases Control and Prevention) ;
  • Jung, Daun (Gwangju Center for Infectious Diseases Control and Prevention) ;
  • Bae, So Hyun (Gwangju Center for Infectious Diseases Control and Prevention) ;
  • Ko, HwaPyeong (Infectious Diseases Control Division, Gwangju City Hall)
  • 류소연 (조선대학교 의과대학 예방의학교실) ;
  • 조준휘 (광주광역시 감염병관리지원단) ;
  • 이란 (광주광역시 감염병관리지원단) ;
  • 박소영 (광주광역시 감염병관리지원단) ;
  • 정다운 (광주광역시 감염병관리지원단) ;
  • 배소현 (광주광역시 감염병관리지원단) ;
  • 고화평 (광주광역시청 감염병관리과)
  • Received : 2022.05.13
  • Accepted : 2022.06.07
  • Published : 2022.06.30

Abstract

Objectives: The purpose of this study was to identify the effectiveness of COVID-19 vaccinations on deaths of the COVID-19 cases in some elderly long-term care facilities (LTCF) in Gwangju Metropolitan City. Methods: The study subjects were 659 COVID-19 cases in residents of 7 elderly LTCF, Gwangju, from 21 Dec. 2021 to 28 Jan. 2022. The used variables were confirmed dates for COVID-19, demographic characteristics, co-morbidities, presentation of symptoms, death and vaccination related characteristics including type of vaccine, doses and dates. Vaccination status were classified as not vaccinated, partially and fully vaccinated. The associations of vaccination status and deaths of COVID-19 cases were tested by chi-square test and multiple logistic regression analysis. Results: The rates of not vaccinated, partially vaccinated and fully vaccinated were 19.4%, 10.2% and 70.4%, respectively. The mortality rate of the cases was 6.4%. The death rate by vaccination status was 16.4% in not vaccinated, 15.4% in partially vaccinated and 2.6% in fully vaccinated, showing a statistically significant difference. The adjusted odds ratios (ORs) (95% confidence intervals, CIs) of death compared to fully vaccinated were 7.64 (3.87-16.34) in non-vaccinated, and 6.97 (3.44-14.14) in partially vaccinated. Conclusions: COVID-19 vaccination seems to work effectively in preventing deaths of COVID-19 cases of elderly LTCF residents. This finding support that fully vaccinations in high risk group such as elderly LTCF residents is very important for one of strategies of COVID-19 management.

Keywords

References

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