DOI QR코드

DOI QR Code

Intrathyroid Thyroglossal Duct Cyst Extending into the Mediastinum: A Case Report and Review of Literature

종격동내 위치한 갑상선 내 갑상설관 낭종: 증례 보고 및 문헌 고찰

  • Lee, Chan Mi (Department of Otolaryngology-HNS, Chonbuk National University, Medical School) ;
  • Hong, Yong Tae (Department of Otolaryngology-HNS, Chonbuk National University, Medical School)
  • 이찬미 (전북대학교 의과대학 이비인후과학교실) ;
  • 홍용태 (전북대학교 의과대학 이비인후과학교실)
  • Received : 2021.10.14
  • Accepted : 2021.12.14
  • Published : 2022.05.30

Abstract

Thyroglossal duct cyst (TGDC) is the most common congenital cyst in the neck and usually presents in children. It is most commonly located at the infrahyoid level. However, intrathyroid TGDC in the adult is extremely rare and its pathogenesis remains unclear. Curiously, an intrathyroid TGDC was found on the lateral aspect of the inferior pole of the thyroid gland. Given the unique position of this lesion, and its capacity to stimulate other nodules in the thyroid, it should be differentiated from other lateral neck masses, such as: thymic cysts, branchial cleft cysts, cystic hygroma, lipomas, lymphadenopathies, cervical teratomas, and lymphomas. In this case, a separate cystic mass was found in the right inferior pole of the thyroid gland and extended to the mediastinum. We confirmed it as TGDC by pathology and histological examination.

Keywords

Acknowledgement

This paper was supported by Fund of Biomedical Research Institute of Jeonbuk National University Hospital.

References

  1. Mondin V, Ferlito A, Muzzi E, Silver CE, Fagan JJ, Devaney KO, et al. Thyroglossal duct cyst: Personal experience and literature review. Auris Nasus Larynx. 2008;35:11-25. https://doi.org/10.1016/j.anl.2007.06.001
  2. Shifrin A, Vernick J. A thyroglossal duct cyst presenting as a thyroid nodule in the lateral neck. Thyroid. 2008;18:263-265. https://doi.org/10.1089/thy.2007.0088
  3. McHenry CR, Danish R, Murphy T, Marty JJ. Atypical thyroglossal duct cyst: A rare cause for a solitary cold thyroid nodule in childhood. Am Surg. 1993;59:223-228.
  4. Huang LD, Gao SQ, Dai RJ, Chen DD, He B, Shi HQ, et al. Intra-thyroid thyroglossal duct cyst: A case report and review of literature. Int J Clin Exp Pathol. 2015;8:7229-7233.
  5. North JH Jr, Foley AM, Hamill RL. Intrathyroid cysts of thyroglossal duct origin. Am Surg. 1998;64:886-888.
  6. Choi HJ, Jung JH, Yoo J, Kang SJ, Lee KY, Chun CS, et al. Intra-thyroid thyroglossal duct cyst: A case report. Korean Journal of Pathology. 2007;41:132-134.
  7. Hatada T, Ichii S, Sagayama K, Ishii H, Sugihara A, Terada N, et al. Intrathyroid thyroglossal duct cyst simulating a thyroid nodule. Tumori. 2000;86:250-252. https://doi.org/10.1177/030089160008600313
  8. Johnston R, Wei JL, Maddalozzo J. Intra-thyroid thyroglossal duct cyst as a differential diagnosis of thyroid nodule. Int J Pediatr Otorhinolaryngol. 2003;67:1027-1030. https://doi.org/10.1016/S0165-5876(03)00185-X
  9. Sade J, Rosen Ann G. Thyroglossal cysts and tracts. A histological and histochemical study. Otol Rhinol Laryngol. 1968;77(1):139-145. https://doi.org/10.1177/000348946807700114