Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Validity of the diagnosis of diabetic microvascular complications in Korean national health insurance claim data

  • Kim, Hyung Jun (Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine) ;
  • Park, Moo-Seok (Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine) ;
  • Kim, Jee-Eun (Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine) ;
  • Song, Tae-Jin (Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine)
  • Received : 2021.11.06
  • Accepted : 2022.02.08
  • Published : 2022.04.30
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Abstract

Background: There is inadequate information on the validation of diabetic microvascular complications in the Korean National Health Insurance Service data set. We aimed to validate the diagnostic algorithms regarding the nephropathy, neuropathy, and retinopathy of diabetes. Methods: From various secondary and tertiary medical centers, we selected 6,493 patients aged ≥ 40 years who were diagnosed with diabetic microvascular complications more than once based on codes in the 10th version of the International Classification of Diseases (ICD-10). During 2019 and 2020, we randomly selected the diagnoses of 200 patients, 100 from each of two hospitals. The positive predictive value (PPV), negative predictive value, error rate, sensitivity, and specificity were determined for each diabetic microvascular complication according to the ICD-10 codes, laboratory findings, diagnostic studies, and treatment procedure codes. Results: Among the 200 patients who visited the hospital more than once and had the diagnostic codes of diabetic microvascular complications, 142, 110, and 154 patients were confirmed to have the gold standard of diabetic nephropathy (PPV, 71.0%), diabetic neuropathy (PPV, 55.0%), and diabetic retinopathy (PPV, 77.0%), respectively. The PPV and specificity of diabetic nephropathy (PPV, 71.0-81.4%; specificity, 10.3-53.4%), diabetic neuropathy (PPV, 55.0-81.3%; specificity, 66.7-76.7%) and diabetic retinopathy (PPV, 77.0-96.6%; specificity, 2.2-89.1%) increased after combining them with the laboratory findings, diagnostic studies, and treatment procedures codes. These change trends were observed similarly for both hospitals. Conclusions: Defining diabetic microvascular complications using ICD-10 codes and their related examination codes may be a feasible method for studying diabetic complications.

Keywords

Acknowledgement

This project was supported by a grant from the Basic Science Research Program through the National Research Foundation of Korea, funded by the Ministry of Education (grant number 2021R1F1A1048113). This work was supported by an Ewha Womans University Research Grant awarded in 2018.

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