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The Effectiveness of Moxibustion Treatment in Infertility with IVF-ET: A Systematic Review and Meta-Analysis

보조생식술을 시행한 난임환자에서의 뜸 치료에 대한 체계적 문헌고찰 및 메타분석

  • Lee, Ho-Sung (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Park, Yong-Duk (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Lee, Hye-Jung (Dept. of Obstetrics & Gynecology, College of Korean Medicine, Kyung Hee University) ;
  • Hwang, Deok-Sang (Dept. of Obstetrics & Gynecology, College of Korean Medicine, Kyung Hee University) ;
  • Jang, Jun-Bock (Dept. of Obstetrics & Gynecology, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Chang-Hoon (Dept. of Obstetrics & Gynecology, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Jin-Moo (Dept. of Obstetrics & Gynecology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Dong-Il (Dept. of Obstetrics & Gynecology, College of Korean Medicine, Dong-Guk University)
  • 이호성 (경희대학교 대학원 임상한의학과) ;
  • 박용덕 (경희대학교 대학원 임상한의학과) ;
  • 이혜정 (경희대학교 한의과대학 부인과교실) ;
  • 황덕상 (경희대학교 한의과대학 부인과교실) ;
  • 장준복 (경희대학교 한의과대학 부인과교실) ;
  • 이창훈 (경희대학교 한의과대학 부인과교실) ;
  • 이진무 (경희대학교 한의과대학 부인과교실) ;
  • 김동일 (동국대학교 한의과대학 부인과교실)
  • Received : 2022.04.15
  • Accepted : 2022.05.27
  • Published : 2022.05.27

Abstract

Objectives: The purpose of this study is to investigate the effectiveness of moxibustion in infertility with In Vitro Fertilization and Embryo Transfer (IVF-ET). Methods: We searched 8 databases (Embase, PubMed, CiNii, CNKI, OASIS, ScienceOn, KMBASE, KISS)to identify eligible studies published before 2021 Oct. We included randomized controlled clinical trials (RCTs) using moxibustion in infertility with IVF-ET. The methodological quality of each RCT was assessed by the Cochrane risk of bias tool. Results: Two RCT studies were eligible in our review. The overall risk of bias was evaluated as unclear. The meta-analysis of 2 trials indicated that favorable results for the use of moxibustion with IVF-ET. Conclusions: This systematic review and meta-analysis of clinical trials suggests that moxibustion with IVF-ET can effect on Infertility patients. However, because of studies included analysis was biased due to unclear risk of bias and unreliable study design, future RCT studies and additional Meta-Analysis are needed to judge the supplementary treatment role of moxibustion in infertility with IVF-ET.

Keywords

Acknowledgement

본 연구는 한국보건산업진흥원을 통해 보건복지부 한의약선도기술개발사업의 재정 지원을 받아 수행된 연구임(HF21C0028000021).

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