한국동물위생학회지 (Korean Journal of Veterinary Service)

  • 제45권1호
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  • Pages.63-69
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  • 2022
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  • 3022-7372(pISSN)
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  • 2287-7630(eISSN)
한국동물위생학회 (The Korean Society of Veterinary Service)
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제주지역 돼지에서 증식성 괴사성 폐렴의 원인체 검출

Detection of etiological agents of proliferative and necrotizing pneumonia in pigs in Jeju

  • 김재훈 (경기도 동물위생시험소) ;
  • 정지열 (제주대학교 수의과대학 및 수의과학연구소) ;
  • 양형석 (제주특별자치도 동물위생시험소) ;
  • 김재훈 (제주대학교 수의과대학 및 수의과학연구소)
  • Kim, Jae-Hoon (Gyeonggi Province Animal Hygiene Laboratory) ;
  • Jung, Ji-Youl (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Yang, Hyoung-Seok (Jeju Self-Governing Provincial Veterinary Research Institute) ;
  • Kim, Jae-Hoon (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)
  • 투고 : 2022.03.17
  • 심사 : 2022.03.29
  • 발행 : 2022.03.30
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초록

Proliferative and necrotizing pneumonia (PNP) is a form of interstitial pneumonia that occurs in post-weaning pigs. In this study, we investigated the presence of swine influenza virus (SIV), porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2) and Aujeszky's disease virus (ADV) in PNP lesions in Jeju pigs. Based on the histopathologic criteria for PNP, a total of 50 cases were selected in Jeju pigs between 2008 and 2010. Coupled with histopathological examinations, the presence of ADV and SIV by polymerase chain reaction (PCR) and reverse transcription PCR (RT-PCR) and PRRSV and PCV2 by immunohistochemical (IHC) methods were investigated. Based on the PCR and RT-PCR methods, ADV and SIV nucleic acids were not detected in all cases. According to IHC, PRRSV was detected in 38 of the 50 cases examined (76%) and PCV2 in 25 cases (50%). PRRSV or PCV2 were detected in 19 (38%) or 6 (12%) cases, respectively. Both PRRSV and PCV2 were identified in other 19 cases (38%). Antigens of PRRSV and PCV2 were commonly observed in the cytoplasm of macrophages and clusters of necrotic cells in alveolar cavities. The results of the present study demonstrate that PRRSV is predominantly associated with PNP in Jeju pigs. Co-infection with PRRSV and PCV2 may enhance the severity of PNP lesions in affected pigs.

키워드

과제정보

This research was supported by the 2022 education, research and student guidance grant funded by Jeju National University.

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