Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Delayed Clinical Signs Associated with Cerebellar Lesion in Holstein Calf Infected with Bovine Viral Diarrhea Virus

  • Choi, Woojae (Department of Farm Animal Medicine, College of Veterinary Medicine, Seoul National University) ;
  • Ro, Younghye (Farm Animal Clinical Training and Research Center, Institute of Green-Bio Science and Technology, Seoul National University) ;
  • Hong, Leegon (Department of Farm Animal Medicine, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Eunkyung (Farm Animal Clinical Training and Research Center, Institute of Green-Bio Science and Technology, Seoul National University) ;
  • Choe, Eunhui (Farm Animal Clinical Training and Research Center, Institute of Green-Bio Science and Technology, Seoul National University) ;
  • Kim, Danil (Department of Farm Animal Medicine, College of Veterinary Medicine, Seoul National University)
  • Received : 2022.02.03
  • Accepted : 2022.02.09
  • Published : 2022.02.28
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Abstract

A 5-month-old Holstein downer calf was presented, and bovine viral diarrhea virus was detected in the feces and the cerebrospinal fluid. Combined treatment of recombinant bovine somatotropin (rBST) administration and standing rehabilitation had been performed for two months, and the calf could maintain the standing position for a while. However, the symptoms were not improved, and the calf died due to ruminal tympany and aspiration pneumonia. Megaesophagus, abomasal ulcer, and a normal-sized but softened cerebellum were observed in clinical necropsy. Improvement of symptoms was confirmed by rBST, but was not reached the complete recovery of gait and standing position.

Keywords

Acknowledgement

We are thankful to LG Chem, Ltd. which greatly assisted the research and provided the recombinant bovine somatotropin (Bustin®-s).

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