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Korean Medicine Treatments with Joripewon-tang for Chemotherapy-Induced Peripheral Neuropathy of Ovarian Cancer : Case Report

난소암의 항암화학요법 유발 만성 말초신경병증의 조리폐원탕 및 복합한의치료 치험 1례

  • Ji-yoon, Yeum (Department of Sasang Constitutional Medicine, Woosuk University Korean Medicine Hospital) ;
  • Su-hyun, Kim (Department of Sasang Constitutional Medicine, Wonkwang University Korean Medicine Hospital) ;
  • Seung-yun, Oh (Department of Sasang Constitutional Medicine, Woosuk University Korean Medicine Hospital) ;
  • Soo-jung, Park (Department of Sasang Constitutional Medicine, Wonkwang University Korean Medicine Hospital)
  • 염지윤 (우석대학교 부속한방병원 사상체질과) ;
  • 김수현 (원광대학교 전주한방병원 사상체질과) ;
  • 오승윤 (우석대학교 부속한방병원 사상체질과) ;
  • 박수정 (원광대학교 전주한방병원 사상체질과)
  • Received : 2022.11.19
  • Accepted : 2022.12.14
  • Published : 2022.12.31

Abstract

Objective: This case report represented that Korean traditional medicine therapies can make effective results for chemotherapy-induced peripheral neuropathy(CIPN) patients. Methods: A 63-year-old female patient has been diagnosed with ovarian cancer(Sertoli-Leydig cell tumor). Total excision of uterus and appendages was operated, and Bleomycin, etoposide and cisplatin combination therapy was applied. After three cycles of chemotherapy, the severe side effects of neutropenia and CIPN occurred. Chemotherapy was terminated, but numbness and tingling pains in the limbs persisted for several months. We provided Korean medicine treatments including herbal medicine, pharmacopuncture, acupuncture, moxibustion and physiotherapies. Results: After treatments, the numbness and pain were reduced from 10 to 1 in hand and 6 to 0 on the numeric rating scale(NRS). Functional assessment of cancer therapy/Gynecologic oncology group neurotoxicity (FACT/GOG-NTX) score was improved from 58 to 97. Conclusion: According to these results, Korean medicine treatments could be considered effective for CIPN. Prospective studies are needed to confirm and expand these findings.

Keywords

References

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