Journal of Korean Traditional Oncology (대한암한의학회지)

Korean Association of Traditional Oncology (대한암한의학회)
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Recent Trend in Clinical Research of Tongue Diagnosis of Cancer Patient

암 환자의 설진에 대한 최신 연구 동향

  • Jaeho, Song (Department of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong) ;
  • Su Bin, Park (Department of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong) ;
  • Jee-Hyun, Yoon (Department of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong) ;
  • Eun Hye, Kim (Department of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong) ;
  • Seong Woo, Yoon (Department of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong)
  • 송재호 (강동경희대학교한방병원 한방내과) ;
  • 박수빈 (강동경희대학교한방병원 한방내과) ;
  • 윤지현 (강동경희대학교한방병원 한방내과) ;
  • 김은혜 (강동경희대학교한방병원 한방내과) ;
  • 윤성우 (강동경희대학교한방병원 한방내과)
  • Received : 2022.10.11
  • Accepted : 2022.12.14
  • Published : 2022.12.31
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Abstract

Objective: The purpose of this review is to analyze the clinical studies on tongue diagnosis in cancer patients. Methods: Domestic and foreign databases were used, such as Pubmed, google scholar, Wanfang med online, Scopus, and OASIS. Searching keywords were tongue diagnosis, tongue color, tongue fur, tongue inspection, cancer, tumor, neoplasm, carcinoma, etc. Studies on tongue diagnosis in cancer patients were included. The published year was limited from 2000 to June 2022. Results: Thirteen studies were enrolled. All selected studies were cross-sectional studies. Cancer patients tend to have a dark and blue-purple tongue, thick fur, yellow fur, fissure tongue, and red dots on the tongue compared with non-cancer patients. With the aggravation of cancer, the rate of patients having dark or blue, or purple tongues increased, and the patients' sublingual veins became wide and tortuous. Conclusion: This study suggests that cancer patients tend to have distinct features of tongue diagnosis. Further researches are warranted.

Keywords

Acknowledgement

본 연구는 보건복지부의 재원으로 한국보건산업진흥원의 보건의료기술연구개발사업 지원에 의하여 이루어진 것임(HF20C0038).

References

  1. Shin YJ, Kim YB, Nam HJ, Kim KS, Cha JH. A literature review on diagnostic importance of tongue diagnosis. The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology 20(3):118-26, 2007 
  2. Kim BNR, Oh MS. A Study on Clinical Application of Tongue Diagnosis. Journal of Korean Medicine Rehabilitation 23(3):149-57, 2013 
  3. Park YJ, Park YB. Objective Evaluation of Sublingual Veins Using Color Differences. The Journal of Korean Medicine 27(3):201-11, 2006 
  4. Wu TC, Lu CN, Hu WL, Wu KL, Chiang JY, Sheen JM, et al. Tongue diagnosis indices for gastroesophageal reflux disease: A cross-sectional, case-controlled observational study. Medicine (Baltimore) 99(29):e20471, 2020 
  5. Kim J, Son J, Jang S, Nam DH, Han G, Yeo I, et al. Availability of tongue diagnosis system for assessing tongue coating thickness in patients with functional dyspepsia. Evid Based Complement Alternat Med 2013:348272, 2013 
  6. Hsu PC, Wu HK, Huang YC, Chang HH, Lee TC, Chen YP, et al. The tongue features associated with type 2 diabetes mellitus. Medicine (Baltimore) 98(19): 2019 
  7. Chung CJ, Wu CH, Hu WL, Shih CH, Liao YN, Hung YC. Tongue Diagnosis Index of Chronic Kidney Disease. Biomed J S2319-4170(22):00027-0, 2022 
  8. Liang K, Huang X, Chen H, Qiu L, Zhuang Y, Zou C, et al. Tongue diagnosis and treatment in traditional Chinese medicine for severe COVID-19: a case report. Ann Palliat Med 9(4):2400-7, 2020  https://doi.org/10.21037/apm-20-1330
  9. Choi JW, Nam YK, Lee JH, Woo HJ. Review of clinical study over the last 10 years on korean medicine treatment for cancer: Focusing on korean database. Journal of korean medicine rehabilitation 31(4):75-86, 2021  https://doi.org/10.18325/jkmr.2021.31.4.75
  10. Horneber M, Bueschel G, Dennert G, Less D, Ritter E, Zwahlen M. How many cancer patients use complementary and alternative medicine: a systematic review and metaanalysis. Integrative cancer therapies 11(3):187-203, 2012  https://doi.org/10.1177/1534735411423920
  11. Park SB, Yoon JH, Kim EH, Lee JY, Yoon SW. A Review of Studies Using Syndrome Differentiation Questionnaire in Cancer Patients. Journal of Korean Traditional Oncology 26(1):1-15, 2021  https://doi.org/10.15432/JKTO.2021.26.1.001
  12. 최승훈, 한의학의 종양에 대한 인식과 병리론. 대한한방종양학회지 1(1):11-28, 1995 
  13. Kim BNR, Koog GH, Yang DM, Lee KW, Oh MS. Research Trends for Tongue Diagnosis in Korea. Journal of Haehwa Medicine 21(1):143-50, 2012 
  14. Hsu PC, Wu HK, Chang HH, Chen JM, Chiang JY, Lo LC. A Perspective on Tongue Diagnosis in Patients with Breast Cancer. Evid Based Complement Alternat Med 2021:4441192, 2021 
  15. Lo LC, Cheng TL, Chen YJ, Natsagdorj S, Chiang JY. TCM tongue diagnosis index of early-stage breast cancer. Complement Ther Med 23(5):705-13, 2015  https://doi.org/10.1016/j.ctim.2015.07.001
  16. Lo LC, Cheng TL, Chiang JY, Damdinsuren N. Breast cancer index: a perspective on tongue diagnosis in traditional chinese medicine. J Tradit Complement Med 3(3):194-203, 2013  https://doi.org/10.4103/2225-4110.114901
  17. Song AY, Lou YN, Yang QX, Li DF, Song GH, Huang LQ, et al. Diagnosis of Early Esophageal Cancer Based on TCM Tongue Inspection. Biomedical and Environmental Sciences 33(9):718-22, 2020  https://doi.org/10.3967/bes2020.094
  18. Duan JL, Deng B, Song GH, Chen ZF, Gong YW, He YH, et al. Application of Computer-Aided Tongue Inspection for Preliminary Screening of Esophageal Cancer. Chin J Integr Med 24(10):746-51, 2018  https://doi.org/10.1007/s11655-018-2840-6
  19. Liu Q, Yue XQ, Ren RZ, Ma CH, Ling CQ. Characteristics of sublingual venae in primary liver cancer patients in different clinical stages. J Chin Integr Med 2(3):175-7, 2004  https://doi.org/10.3736/jcim20040306
  20. Liu Q, Yue XQ, Deng WZ, Ren RZ. Quantitative study on tongue color in primary liver cancer patients by analysis system for comprehensive information of tongue diagnosis. J Chin Integr Med 1(3):180-3, 2003  https://doi.org/10.3736/jcim20030310
  21. Hwang HI, So JM, Han MG, Yong WH. Comparative study of tongue image between lung cancer and general respiratory diseases. J Tradit Chin Med 43(7):535-6, 2002  https://doi.org/10.3321/j.issn:1001-1668.2002.07.033
  22. Hu J, Han S, Chen Y, Ji Z. Variations of Tongue Coating Microbiota in Patients with Gastric Cancer. Biomed Res Int 2015:173729, 2015 
  23. Han S, Chen Y, Hu J, Ji Z. Tongue images and tongue coating microbiome in patients with colorectal cancer. Microb Pathog 77:1-6, 2014  https://doi.org/10.1016/j.micpath.2014.10.003
  24. Hao J, Zhu C, Cao R, Yang X, Ding X, Man Y, et al. Purple-bluish tongue is associated with platelet counts, and the recurrence of epithelial ovarian cancer. J Tradit Chin Med 36(3):321-5, 2016  https://doi.org/10.1016/S0254-6272(16)30044-9
  25. Han S, Yang X, Qi Q, Pan Y, Chen Y, Shen J, et al. Potential screening and early diagnosis method for cancer: tongue diagnosis. International journal of oncology 48(6):2257-64, 2016  https://doi.org/10.3892/ijo.2016.3466
  26. Eo YH, Kim JE, Yoo HS, Park KM. Color Characteristic on Tongue Image of Malignant Neoplasm Patients. Journal of Physiology & Pathology in Korean Medicine 19(5):1437-42, 2005 
  27. Jung CJ, Jeon YJ, Kim JY, Kim KH. Review on the current trends in tongue diagnosis systems. Integrative Medicine Research 1(1):13-20, 2012  https://doi.org/10.1016/j.imr.2012.09.001
  28. Cheon C, Park S, Jang BH, Shin Y, Ko SG. The Analysis of usage of Symptom Differentiation in Clinical Trials in Korean Medicine for Cancer Patients. Journal of Society of Preventive Korean Medicine 19(1):61-70, 2015 
  29. Lim JW, Yoo HS, Cho JH, Son CK, Lee YW, Cho CK. Study on relation between tongue diagnosis with cancer: a review of literature. The Journal of Korean Oriental oncology 9(1):89-97, 2003