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http://dx.doi.org/10.15432/JKTO.2022.27.1.013

Recent Trend in Clinical Research of Tongue Diagnosis of Cancer Patient  

Jaeho, Song (Department of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong)
Su Bin, Park (Department of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong)
Jee-Hyun, Yoon (Department of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong)
Eun Hye, Kim (Department of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong)
Seong Woo, Yoon (Department of Korean Internal Medicine, Kyung Hee University Hospital at Gangdong)
Publication Information
Journal of Korean Traditional Oncology / v.27, no.1, 2022 , pp. 13-23 More about this Journal
Abstract
Objective: The purpose of this review is to analyze the clinical studies on tongue diagnosis in cancer patients. Methods: Domestic and foreign databases were used, such as Pubmed, google scholar, Wanfang med online, Scopus, and OASIS. Searching keywords were tongue diagnosis, tongue color, tongue fur, tongue inspection, cancer, tumor, neoplasm, carcinoma, etc. Studies on tongue diagnosis in cancer patients were included. The published year was limited from 2000 to June 2022. Results: Thirteen studies were enrolled. All selected studies were cross-sectional studies. Cancer patients tend to have a dark and blue-purple tongue, thick fur, yellow fur, fissure tongue, and red dots on the tongue compared with non-cancer patients. With the aggravation of cancer, the rate of patients having dark or blue, or purple tongues increased, and the patients' sublingual veins became wide and tortuous. Conclusion: This study suggests that cancer patients tend to have distinct features of tongue diagnosis. Further researches are warranted.
Keywords
cancer; tongue diagnosis; diagnosis; traditional Korean medicine; review;
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Times Cited By KSCI : 3  (Citation Analysis)
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1 Shin YJ, Kim YB, Nam HJ, Kim KS, Cha JH. A literature review on diagnostic importance of tongue diagnosis. The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology 20(3):118-26, 2007 
2 Kim BNR, Oh MS. A Study on Clinical Application of Tongue Diagnosis. Journal of Korean Medicine Rehabilitation 23(3):149-57, 2013 
3 Park YJ, Park YB. Objective Evaluation of Sublingual Veins Using Color Differences. The Journal of Korean Medicine 27(3):201-11, 2006 
4 Wu TC, Lu CN, Hu WL, Wu KL, Chiang JY, Sheen JM, et al. Tongue diagnosis indices for gastroesophageal reflux disease: A cross-sectional, case-controlled observational study. Medicine (Baltimore) 99(29):e20471, 2020 
5 Kim J, Son J, Jang S, Nam DH, Han G, Yeo I, et al. Availability of tongue diagnosis system for assessing tongue coating thickness in patients with functional dyspepsia. Evid Based Complement Alternat Med 2013:348272, 2013 
6 Hsu PC, Wu HK, Huang YC, Chang HH, Lee TC, Chen YP, et al. The tongue features associated with type 2 diabetes mellitus. Medicine (Baltimore) 98(19): 2019 
7 Chung CJ, Wu CH, Hu WL, Shih CH, Liao YN, Hung YC. Tongue Diagnosis Index of Chronic Kidney Disease. Biomed J S2319-4170(22):00027-0, 2022 
8 Liang K, Huang X, Chen H, Qiu L, Zhuang Y, Zou C, et al. Tongue diagnosis and treatment in traditional Chinese medicine for severe COVID-19: a case report. Ann Palliat Med 9(4):2400-7, 2020    DOI
9 Choi JW, Nam YK, Lee JH, Woo HJ. Review of clinical study over the last 10 years on korean medicine treatment for cancer: Focusing on korean database. Journal of korean medicine rehabilitation 31(4):75-86, 2021    DOI
10 Horneber M, Bueschel G, Dennert G, Less D, Ritter E, Zwahlen M. How many cancer patients use complementary and alternative medicine: a systematic review and metaanalysis. Integrative cancer therapies 11(3):187-203, 2012    DOI
11 Park SB, Yoon JH, Kim EH, Lee JY, Yoon SW. A Review of Studies Using Syndrome Differentiation Questionnaire in Cancer Patients. Journal of Korean Traditional Oncology 26(1):1-15, 2021    DOI
12 최승훈, 한의학의 종양에 대한 인식과 병리론. 대한한방종양학회지 1(1):11-28, 1995 
13 Kim BNR, Koog GH, Yang DM, Lee KW, Oh MS. Research Trends for Tongue Diagnosis in Korea. Journal of Haehwa Medicine 21(1):143-50, 2012 
14 Song AY, Lou YN, Yang QX, Li DF, Song GH, Huang LQ, et al. Diagnosis of Early Esophageal Cancer Based on TCM Tongue Inspection. Biomedical and Environmental Sciences 33(9):718-22, 2020    DOI
15 Hsu PC, Wu HK, Chang HH, Chen JM, Chiang JY, Lo LC. A Perspective on Tongue Diagnosis in Patients with Breast Cancer. Evid Based Complement Alternat Med 2021:4441192, 2021 
16 Lo LC, Cheng TL, Chen YJ, Natsagdorj S, Chiang JY. TCM tongue diagnosis index of early-stage breast cancer. Complement Ther Med 23(5):705-13, 2015    DOI
17 Lo LC, Cheng TL, Chiang JY, Damdinsuren N. Breast cancer index: a perspective on tongue diagnosis in traditional chinese medicine. J Tradit Complement Med 3(3):194-203, 2013    DOI
18 Duan JL, Deng B, Song GH, Chen ZF, Gong YW, He YH, et al. Application of Computer-Aided Tongue Inspection for Preliminary Screening of Esophageal Cancer. Chin J Integr Med 24(10):746-51, 2018    DOI
19 Liu Q, Yue XQ, Ren RZ, Ma CH, Ling CQ. Characteristics of sublingual venae in primary liver cancer patients in different clinical stages. J Chin Integr Med 2(3):175-7, 2004    DOI
20 Liu Q, Yue XQ, Deng WZ, Ren RZ. Quantitative study on tongue color in primary liver cancer patients by analysis system for comprehensive information of tongue diagnosis. J Chin Integr Med 1(3):180-3, 2003    DOI
21 Hwang HI, So JM, Han MG, Yong WH. Comparative study of tongue image between lung cancer and general respiratory diseases. J Tradit Chin Med 43(7):535-6, 2002    DOI
22 Hu J, Han S, Chen Y, Ji Z. Variations of Tongue Coating Microbiota in Patients with Gastric Cancer. Biomed Res Int 2015:173729, 2015 
23 Han S, Chen Y, Hu J, Ji Z. Tongue images and tongue coating microbiome in patients with colorectal cancer. Microb Pathog 77:1-6, 2014    DOI
24 Jung CJ, Jeon YJ, Kim JY, Kim KH. Review on the current trends in tongue diagnosis systems. Integrative Medicine Research 1(1):13-20, 2012    DOI
25 Hao J, Zhu C, Cao R, Yang X, Ding X, Man Y, et al. Purple-bluish tongue is associated with platelet counts, and the recurrence of epithelial ovarian cancer. J Tradit Chin Med 36(3):321-5, 2016    DOI
26 Han S, Yang X, Qi Q, Pan Y, Chen Y, Shen J, et al. Potential screening and early diagnosis method for cancer: tongue diagnosis. International journal of oncology 48(6):2257-64, 2016    DOI
27 Eo YH, Kim JE, Yoo HS, Park KM. Color Characteristic on Tongue Image of Malignant Neoplasm Patients. Journal of Physiology & Pathology in Korean Medicine 19(5):1437-42, 2005 
28 Cheon C, Park S, Jang BH, Shin Y, Ko SG. The Analysis of usage of Symptom Differentiation in Clinical Trials in Korean Medicine for Cancer Patients. Journal of Society of Preventive Korean Medicine 19(1):61-70, 2015 
29 Lim JW, Yoo HS, Cho JH, Son CK, Lee YW, Cho CK. Study on relation between tongue diagnosis with cancer: a review of literature. The Journal of Korean Oriental oncology 9(1):89-97, 2003