과제정보
This study was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2017R1D1A1B03032457) and Hankuk University of Foreign Studies Research Fund.
참고문헌
- Ioannidis JP. The mass production of redundant, misleading, and conflicted systematic reviews and meta-analyses. Milbank Q 2016;94:485-514. https://doi.org/10.1111/1468-0009.12210
- Pan Z, Trikalinos TA, Kavvoura FK, Lau J, Ioannidis JP. Local literature bias in genetic epidemiology: an empirical evaluation of the Chinese literature. PLoS Med 2005;2:e334. https://doi.org/10.1371/journal.pmed.0020334
- Park JH, Eisenhut M, van der Vliet HJ, Shin JI. Statistical controversies in clinical research: overlap and errors in the meta-analyses of microRNA genetic association studies in cancers. Ann Oncol 2017;28:1169-82. https://doi.org/10.1093/annonc/mdx024
- Jeong DY, Lee SW, Park YH, Choi JH, Kwon YW, Moon G, et al. Genetic variation and systemic lupus erythematosus: A field synopsis and systematic meta-analysis. Autoimmun Rev 2018;17:553-66. https://doi.org/10.1016/j.autrev.2017.12.011
- Park JH, Geum DI, Eisenhut M, van der Vliet HJ, Shin JI. Bayesian statistical methods in genetic association studies: Empirical examination of statistically non-significant Genome Wide Association Study (GWAS) meta-analyses in cancers: A systematic review. Gene 2019;685:170-8. https://doi.org/10.1016/j.gene.2018.10.057
- McCarthy MI, Abecasis GR, Cardon LR, Goldstein DB, Little J, Ioannidis JP, et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 2008;9:356-69. https://doi.org/10.1038/nrg2344
- Panagiotou OA, Ioannidis JP, Genome-Wide Significance P. What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations. Int J Epidemiol 2012;41:273-86. https://doi.org/10.1093/ije/dyr178
- Maraganore DM, de Andrade M, Lesnick TG, Strain KJ, Farrer MJ, Rocca WA, et al. High-resolution whole-genome association study of Parkinson disease. Am J Hum Genet 2005;77:685-93. https://doi.org/10.1086/496902
- Stacey SN, Manolescu A, Sulem P, Rafnar T, Gudmundsson J, Gudjonsson SA, et al. Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 2007;39:865-9. https://doi.org/10.1038/ng2064
- Zanke BW, Greenwood CM, Rangrej J, Kustra R, Tenesa A, Farrington SM, et al. Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet 2007;39:989-94. https://doi.org/10.1038/ng2089
- Hoggart CJ, Clark TG, De Iorio M, Whittaker JC, Balding DJ. Genome-wide significance for dense SNP and resequencing data. Genet Epidemiol 2008;32:179-85. https://doi.org/10.1002/gepi.20292
- Wacholder S, Chanock S, Garcia-Closas M, El Ghormli L, Rothman N. Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst 2004;96:434-42. https://doi.org/10.1093/jnci/djh075
- Wakefield J. A Bayesian measure of the probability of false discovery in genetic epidemiology studies. Am J Hum Genet 2007;81:208-27. https://doi.org/10.1086/519024
- Barrdahl M, Rudolph A, Hopper JL, Southey MC, Broeks A, Fasching PA, et al. Gene-environment interactions involving functional variants: Results from the Breast Cancer Association Consortium. Int J Cancer 2017;141:1830-40. https://doi.org/10.1002/ijc.30859
- Braem MG, Schouten LJ, Peeters PH, van den Brandt PA, Onland-Moret NC. Genetic susceptibility to sporadic ovarian cancer: a systematic review. Biochim Biophys Acta 2011;1816:132-46.
- Dong LM, Potter JD, White E, Ulrich CM, Cardon LR, Peters U. Genetic susceptibility to cancer: the role of polymorphisms in candidate genes. JAMA 2008;299:2423-36. https://doi.org/10.1001/jama.299.20.2423
- Engels EA, Wu X, Gu J, Dong Q, Liu J, Spitz MR. Systematic evaluation of genetic variants in the inflammation pathway and risk of lung cancer. Cancer Res 2007;67:6520-7. https://doi.org/10.1158/0008-5472.CAN-07-0370
- Montazeri Z, Theodoratou E, Nyiraneza C, Timofeeva M, Chen W, Svinti V, et al. Systematic meta-analyses and field synopsis of genetic association studies in colorectal adenomas. Int J Epidemiol 2016;45:186-205. https://doi.org/10.1093/ije/dyv185
- Pathak A, Wenzlaff AS, Hyland PL, Cote ML, Keele GR, Land S, et al. Apoptosis-related single nucleotide polymorphisms and the risk of non-small cell lung cancer in women. J Cancer Ther Res 2014;3:10.7243/2049-7962-3-1.
- Theodoratou E, Montazeri Z, Hawken S, Allum GC, Gong J, Tait V, et al. Systematic meta-analyses and field synopsis of genetic association studies in colorectal cancer. J Natl Cancer Inst 2012;104:1433-57. https://doi.org/10.1093/jnci/djs369
- Vijayakrishnan J, Houlston RS. Candidate gene association studies and risk of childhood acute lymphoblastic leukemia: a systematic review and meta-analysis. Haematologica 2010;95:1405-14. https://doi.org/10.3324/haematol.2010.022095
- Lucke JF. A critique of the false-positive report probability. Genet Epidemiol 2009;33:145-50. https://doi.org/10.1002/gepi.20363
- Crow MK. Advances in understanding the role of type I interferons in systemic lupus erythematosus. Curr Opin Rheumatol 2014;26:467-74. https://doi.org/10.1097/BOR.0000000000000087
- Ghodke-Puranik Y, Niewold TB. Genetics of the type I interferon pathway in systemic lupus erythematosus. Int J Clin Rheumtol 2013;8.
- Blanco P, Palucka AK, Gill M, Pascual V, Banchereau J. Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science 2001;294:1540-3. https://doi.org/10.1126/science.1064890
- Niewold TB. Interferon alpha as a primary pathogenic factor in human lupus. J Interferon Cytokine Res 2011;31:887-92. https://doi.org/10.1089/jir.2011.0071
- Beyaert R, Heyninck K, Van Huffel S. A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis. Biochem Pharmacol 2000;60:1143-51. https://doi.org/10.1016/S0006-2952(00)00404-4
- Ghodke-Puranik Y, Niewold TB. Immunogenetics of systemic lupus erythematosus: A comprehensive review. J Autoimmun 2015;64:125-36. https://doi.org/10.1016/j.jaut.2015.08.004
- Sevimoglu T, Arga KY. The role of protein interaction networks in systems biomedicine. Comput Struct Biotechnol J 2014;11:22-7. https://doi.org/10.1016/j.csbj.2014.08.008
- Taye B, Vaz C, Tanavde V, Kuznetsov VA, Eisenhaber F, Sugrue RJ, et al. Benchmarking selected computational gene network growing tools in context of virus-host interactions. Sci Rep 2017;7:5805. https://doi.org/10.1038/s41598-017-06020-6
- Warde-Farley D, Donaldson SL, Comes O, Zuberi K, Badrawi R, Chao P, et al. The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function. Nucleic Acids Res 2010;38:W214-20. https://doi.org/10.1093/nar/gkq537
- Franceschini A, Szklarczyk D, Frankild S, Kuhn M, Simonovic M, Roth A, et al. STRING v9.1: protein-protein interaction networks, with increased coverage and integration. Nucleic Acids Res 2013;41:D808-15. https://doi.org/10.1093/nar/gks1094
- Ko Y, Cho M, Lee JS, Kim J. Identification of disease comorbidity through hidden molecular mechanisms. Sci Rep 2016;6:39433. https://doi.org/10.1038/srep39433
- Cline MS, Smoot M, Cerami E, Kuchinsky A, Landys N, Workman C, et al. Integration of biological networks and gene expression data using Cytoscape. Nat Protoc 2007;2:2366-82. https://doi.org/10.1038/nprot.2007.324
- Bentham J, Morris DL, Graham DSC, Pinder CL, Tombleson P, Behrens TW, et al. Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. Nat Genet 2015;47:1457-64. https://doi.org/10.1038/ng.3434
- Oparina NY, Delgado-Vega AM, Martinez-Bueno M, Magro-Checa C, Fernandez C, Castro RO, et al. PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6. Ann Rheum Dis 2015;74:e14. https://doi.org/10.1136/annrheumdis-2013-204909
- Vaughn SE, Foley C, Lu X, Patel ZH, Zoller EE, Magnusen AF, et al. Lupus risk variants in the PXK locus alter B-cell receptor internalization. Front Genet 2014;5:450.
- National Center for Biotechnology Information. RefSeq: NCBI Reference Sequence Database [Internet]. Bethesda (MD): National Center for Biotechnology Information; [cited 2020 April 9]. Available from: https://www.ncbi.nlm.nih.gov/refseq/.
- Lessard CJ, Sajuthi S, Zhao J, Kim K, Ice JA, Li H, et al. Identification of a systemic lupus erythematosus risk locus spanning ATG16L2, FCHSD2, and P2RY2 in Koreans. Arthritis Rheumatol 2016;68:1197-209. https://doi.org/10.1002/art.39548
- Zhang Y, Yang J, Zhang J, Sun L, Hirankarn N, Pan HF, et al. Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations. Ann Rheum Dis 2016;75:891-8. https://doi.org/10.1136/annrheumdis-2014-206367
- Molineros JE, Yang W, Zhou XJ, Sun C, Okada Y, Zhang H, et al. Confirmation of five novel susceptibility loci for systemic lupus erythematosus (SLE) and integrated network analysis of 82 SLE susceptibility loci. Hum Mol Genet 2017;26:1205-16. https://doi.org/10.1093/hmg/ddx026
- Morris DL, Sheng Y, Zhang Y, Wang YF, Zhu Z, Tombleson P, et al. Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus. Nat Genet 2016;48:940-6. https://doi.org/10.1038/ng.3603
- Bergeron D. Identification et caracterisation d'une deuxieme proteine codee par le gene ATXN1. Sherbrooke (CA): Universite de Sherbrooke, 2013.
- Oyake T, Itoh K, Motohashi H, Hayashi N, Hoshino H, Nishizawa M, et al. Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol Cell Biol 1996;16:6083-95. https://doi.org/10.1128/MCB.16.11.6083
- Vahedi G, Kanno Y, Furumoto Y, Jiang K, Parker SC, Erdos MR, et al. Super-enhancers delineate disease-associated regulatory nodes in T cells. Nature 2015;520:558-62. https://doi.org/10.1038/nature14154
- Yokoyama K, Su Ih, Tezuka T, Yasuda T, Mikoshiba K, Tarakhovsky A, et al. BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP3 receptor. EMBO J 2002;21:83-92. https://doi.org/10.1093/emboj/21.1.83
- Lee YH, Bae SC, Choi SJ, Ji JD, Song GG. Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis. Mol Biol Rep 2012;39:10627-35. https://doi.org/10.1007/s11033-012-1952-x
- Lee YH, Bae SC, Choi SJ, Ji JD, Song GG. Associations between the functional CD40 rs4810485 G/T polymorphism and susceptibility to rheumatoid arthritis and systemic lupus erythematosus: a meta-analysis. Lupus 2015;24:1177-83. https://doi.org/10.1177/0961203315583543
- Lessard CJ, Adrianto I, Kelly JA, Kaufman KM, Grundahl KM, Adler A, et al. Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. Am J Hum Genet 2011;88:83-91. https://doi.org/10.1016/j.ajhg.2010.11.014
- Sheng YJ, Xu JH, Wu YG, Zuo XB, Gao JP, Lin Y, et al. Association analyses confirm five susceptibility loci for systemic lupus erythematosus in the Han Chinese population. Arthritis Res Ther 2015;17:85. https://doi.org/10.1186/s13075-015-0602-9
- Shojaa M, Aghaie M, Qorbani M, Khashayar P, Amoli M, Keshtkar AA, et al. Association of the CTLA-4 1722TC polymorphism and systemic lupus erythematosus: a systematic review and meta analysis. Med J Islam Repub Iran 2014;28:132.
- Zhang J, Zhang Y, Yang J, Zhang L, Sun L, Pan HF, et al. Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians. Hum Mol Genet 2014;23:524-33. https://doi.org/10.1093/hmg/ddt424
- Odhams CA, Roberts AL, Vester SK, Duarte CST, Beales CT, Clarke AJ, et al. Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus. Nat Commun 2019;10:2164. https://doi.org/10.1038/s41467-019-10106-2
- Wang C, Ahlford A, Jarvinen TM, Nordmark G, Eloranta ML, Gunnarsson I, et al. Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations. Eur J Hum Genet 2013;21: 994-9. https://doi.org/10.1038/ejhg.2012.277
- Yang W, Shen N, Ye DQ, Liu Q, Zhang Y, Qian XX, et al. Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. PLoS Genet 2010;6:e1000841. https://doi.org/10.1371/journal.pgen.1000841
- Zhu XW, Wang Y, Wei YH, Zhao PP, Wang XB, Rong JJ, et al. Comprehensive assessment of the association between FCGRs polymorphisms and the risk of systemic lupus erythematosus: evidence from a meta-analysis. Sci Rep 2016;6:31617. https://doi.org/10.1038/srep31617
- Zhang Y, Zhang J, Yang J, Wang Y, Zhang L, Zuo X, et al. Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus. Hum Mol Genet 2015;24:274-84. https://doi.org/10.1093/hmg/ddu429
- Niu Z, Zhang P, Tong Y. Value of HLA-DR genotype in systemic lupus erythematosus and lupus nephritis: a meta-analysis. Int J Rheum Dis 2015;18:17-28. https://doi.org/10.1111/1756-185X.12528
- Castano-Rodriguez N, Diaz-Gallo LM, Pineda-Tamayo R, Rojas-Villarraga A, Anaya JM. Meta-analysis of HLA-DRB1 and HLA-DQB1 polymorphisms in Latin American patients with systemic lupus erythematosus. Autoimmun Rev 2008;7:322-30. https://doi.org/10.1016/j.autrev.2007.12.002
- Lee YH, Bae SC, Song GG. Meta-analysis of associations between functional HLA-G polymorphisms and susceptibility to systemic lupus erythematosus and rheumatoid arthritis. Rheumatol Int 2015;35:953-61. https://doi.org/10.1007/s00296-014-3155-3
- Paul P, Rouas-Freiss N, Khalil-Daher I, Moreau P, Riteau B, Le Gal FA, et al. HLA-G expression in melanoma: a way for tumor cells to escape from immunosurveillance. Proc Natl Acad Sci U S A 1998;95:4510-5. https://doi.org/10.1073/pnas.95.8.4510
- Kim K, Brown EE, Choi CB, Alarcon-Riquelme ME, Biolupus, Kelly JA, et al. Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries. Ann Rheum Dis 2012;71:1809-14. https://doi.org/10.1136/annrheumdis-2011-201110
- J de AS, C A, P SG, S C. Systemic lupus erythematosus: old and new susceptibility genes versus clinical manifestations. Curr Genomics 2014;15:52-65. https://doi.org/10.2174/138920291501140306113715
- Qi JH, Qi J, Xiang LN, Nie G. Association between IL-21 polymorphism and systemic lupus erythematosus: a meta-analysis. Genet Mol Res 2015;14:9595-603. https://doi.org/10.4238/2015.August.14.22
- Webb R, Merrill JT, Kelly JA, Sestak A, Kaufman KM, Langefeld CD, et al. A polymorphism within IL21R confers risk for systemic lupus erythematosus. Arthritis Rheum 2009;60:2402-7. https://doi.org/10.1002/art.24658
- Katkam SK, Rajasekhar L, Kumaraswami K, Kutala VK. Association of IL -6 -174 G>C polymorphism with the risk of SLE among south Indians: evidence from case-control study and meta-analysis. Lupus 2017;26:1491-501. https://doi.org/10.1177/0961203317711010
- Chang Y, Sheng Y, Cheng Y, Lin Y, Zhu Z, Wen L, et al. Downregulated expression of LBH mRNA in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. J Dermatol 2016;43:99-102. https://doi.org/10.1111/1346-8138.13006
- Flesher DL, Sun X, Behrens TW, Graham RR, Criswell LA. Recent advances in the genetics of systemic lupus erythematosus. Expert Rev Clin Immunol 2010;6:461-79. https://doi.org/10.1586/eci.10.8
- Lee YH, Lee HS, Choi SJ, Ji JD, Song GG. The association between the mannose-binding lectin codon 54 polymorphism and systemic lupus erythematosus: a meta-analysis update. Mol Biol Rep 2012;39:5569-74. https://doi.org/10.1007/s11033-011-1361-6
- Webb R, Wren JD, Jeffries M, Kelly JA, Kaufman KM, Tang Y, et al. Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus. Arthritis Rheum 2009;60:1076-84. https://doi.org/10.1002/art.24360
- Tang ZM, Wang P, Chang PP, Hasahya T, Xing H, Wang JP, et al. Association between rs2431697 T allele on 5q33.3 and systemic lupus erythematosus: case-control study and meta-analysis. Clin Rheumatol 2015;34:1893-902. https://doi.org/10.1007/s10067-015-3045-4
- Lee YH, Song GG. Correlation between circulating osteopontin level in systemic lupus erythematosus and disease activity and associations between osteopontin polymorphisms and disease susceptibility: a metaanalysis. Lupus 2017;26:132-8. https://doi.org/10.1177/0961203316655214
- Tan W, Sunahori K, Zhao J, Deng Y, Kaufman KM, Kelly JA, et al. Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups. Arthritis Rheum 2011;63:2755-63. https://doi.org/10.1002/art.30452
- Ramos PS, Criswell LA, Moser KL, Comeau ME, Williams AH, Pajewski NM, et al. A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap. PLoS Genet 2011;7:e1002406. https://doi.org/10.1371/journal.pgen.1002406
- Li Y, He X, Schembri-King J, Jakes S, Hayashi J. Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation. J Immunol 2000;164:5199-206. https://doi.org/10.4049/jimmunol.164.10.5199
- Daniel H, Kottra G. The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology. Pflugers Arch 2004;447:610-8. https://doi.org/10.1007/s00424-003-1101-4
- Kobayashi T, Shimabukuro-Demoto S, Yoshida-Sugitani R, Furuyama-Tanaka K, Karyu H, Sugiura Y, et al. The histidine transporter SLC15A4 coordinates mTOR-dependent inflammatory responses and pathogenic antibody production. Immunity 2014;41:375-88. https://doi.org/10.1016/j.immuni.2014.08.011
- Lee YH, Choi SJ, Ji JD, Song GG. Association between toll-like receptor polymorphisms and systemic lupus erythematosus: a meta-analysis update. Lupus 2016;25:593-601. https://doi.org/10.1177/0961203315622823
- Lessard CJ, Adrianto I, Ice JA, Wiley GB, Kelly JA, Glenn SB, et al. Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. Am J Hum Genet 2012;90:648-60. https://doi.org/10.1016/j.ajhg.2012.02.023
- Bates JS, Lessard CJ, Leon JM, Nguyen T, Battiest LJ, Rodgers J, et al. Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations. Genes Immun 2009;10:470-7. https://doi.org/10.1038/gene.2009.31
- Zhang MY, Yang XK, Pan HF, Ye DQ. Associations between TNFAIP3 gene polymorphisms and systemic lupus erythematosus risk: an updated meta-analysis. HLA 2016;88:245-52. https://doi.org/10.1111/tan.12908
- Yang ZC, Xu F, Tang M, Xiong X. Association between TNF-alpha promoter -308 A/G polymorphism and systemic lupus erythematosus susceptibility: a case-control study and meta-analysis. Scand J Immunol 2017;85:197-210. https://doi.org/10.1111/sji.12516
- Kataoka N, Bachorik JL, Dreyfuss G. Transportin-SR, a nuclear import receptor for SR proteins. J Cell Biol 1999;145:1145-52. https://doi.org/10.1083/jcb.145.6.1145
- Kurreeman FA, Goulielmos GN, Alizadeh BZ, Rueda B, HouwingDuistermaat J, Sanchez E, et al. The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases. Ann Rheum Dis 2010;69:696-9. https://doi.org/10.1136/ard.2008.106567
- Ge M, Yu W, Shi J, Zhang J, Wang M, Feng S, et al. TRAF1/C5 rs10818488 polymorphism is not a genetic risk factor for acquired aplastic anemia in a Chinese population. Hum Immunol 2015;76:19-21.
- Namjou B, Choi CB, Harley IT, Alarcon-Riquelme ME, Network B, Kelly JA, et al. Evaluation of TRAF6 in a large multiancestral lupus cohort. Arthritis Rheum 2012;64:1960-9. https://doi.org/10.1002/art.34361
- Diaz-Gallo LM, Sanchez E, Ortego-Centeno N, Sabio JM, GarciaHernandez FJ, de Ramon E, et al. Evidence of new risk genetic factor to systemic lupus erythematosus: the UBASH3A gene. PLoS One 2013;8:e60646. https://doi.org/10.1371/journal.pone.0060646
- Parmar AS, Lappalainen M, Paavola-Sakki P, Halme L, Farkkila M, Turunen U, et al. Association of celiac disease genes with inflammatory bowel disease in Finnish and Swedish patients. Genes Immun 2012;13: 474-80. https://doi.org/10.1038/gene.2012.21
- Maloverjan A, Piirsoo M, Michelson P, Kogerman P, Osterlund T. Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway. Exp Cell Res 2010;316:627-37. https://doi.org/10.1016/j.yexcr.2009.10.018
- Zhou TB, Jiang ZP, Lin ZJ, Su N. Association of vitamin D receptor gene polymorphism with the risk of systemic lupus erythematosus. J Recept Signal Transduct Res 2015;35:8-14. https://doi.org/10.3109/10799893.2014.922577
- Zhang Y, Wang YF, Yang J, Zhang J, Sun L, Hirankarn N, et al. Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus. Arthritis Res Ther 2015;17:67. https://doi.org/10.1186/s13075-015-0577-6