Animal Bioscience

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
권호 표지
DOI QR코드

DOI QR Code

Effect of Salvia miltiorrhiza aerial parts on growth performance, nutrient digestibility, and digestive enzymes in rabbits

  • Wang, Jiajia (Department of Animal Science, Henan University of Science and Technology) ;
  • Luo, Yiran (Department of Animal Science, Henan University of Science and Technology) ;
  • Li, Pei (Department of Animal Science, Henan University of Science and Technology) ;
  • Zhang, Feike (Luoyang Xintai Agro-pastoral Technology Co., Ltd) ;
  • Liu, Ning (Department of Animal Science, Henan University of Science and Technology)
  • Received : 2021.02.16
  • Accepted : 2021.05.11
  • Published : 2021.12.01
Download PDF
⟨ Previous Next ⟩

Abstract

Objective: This study aimed to investigate the effect of Salvia miltiorrhiza (S.m.) aerial parts as an alternative ingredient on growth performance, nutrient digestibility, and digestive enzymes in growing rabbits. Methods: Treatments included five tested diets: a control (basal diet), antibiotic (basal diet+enramycin at 5 mg/kg), and S.m. aerial parts powder added at 3.0%, 6.0%, and 9.0% of feed using 300 growing rabbits. Results: The diets with S.m. aerial parts addition at 9.0% decreased (p<0.05) feed/gain compared to the control, but there were no differences in feed intake and body weight gain. In contrast with the control, the addition of antibiotic increased (p<0.05) digestibility of dry matter, crude protein, energy, fiber, and ash. The herb addition did not cause differences in the digestibility of most nutrients compared to the antibiotic, but fiber digestibility of the herb at 6.0% and 9.0% was lower (p<0.05) than that of the antibiotic. Moreover, the antibiotic and the herb also similarly increased (p<0.05) the activities of duodenal α-amylase, maltase, lipase, and trypsin, compared to the control, and the herb at 6.0% and 9.0% showed a greater (p<0.05) activity of elastase than the dose 3.0%. Conclusion: The obtained data indicate that S.m. aerial parts can be a potential forage in rabbit's diet at 9.0% with a beneficial regulation on nutrition and digestion.

Keywords

Acknowledgement

The authors thank the animal keepers of Luoyang Xintai Agro-pastoral Technology and laboratory staff of the Animal Nutrition Group, Henan University of Science and Technology, and all colleagues and students for support in practical work.

References

  1. Jia Q, Zhu R, Tian Y, et al. Salvia miltiorrhiza in diabetes: A review of its pharmacology, phytochemistry, and safety. Phytomedicine 2019;58:152871. https://doi.org/10.1016/j.phymed.2019.152871
  2. Ren J, Fu L, Nile SH, Zhang J, Kai G. Salvia miltiorrhiza in treating cardiovascular diseases: A review on its pharmacological and clinical applications. Front Pharmacol 2019;10:753. https://doi.org/10.3389/fphar.2019.00753
  3. Wu Y, Xu S, Tian XY. The Effect of salvianolic acid on vascular protection and possible mechanisms. Oxid Med Cell Longev 2020;2020:5472096. https://doi.org/10.1155/2020/5472096
  4. Jung I, Kim H, Moon S, Lee H, Kim B. Overview of Salvia miltiorrhiza as a potential therapeutic agent for various diseases: an update on efficacy and mechanisms of action. Antioxidants 2020;9:857. https://doi.org/10.3390/antiox9090857
  5. Zeng H, Su S, Xiang X, et al. Comparative analysis of the major chemical constituents in Salvia miltiorrhiza roots, stems, leaves and flowers during different growth periods by UPLC-TQ-MS/MS and HPLC-ELSD methods. Molecules 2017;22:771. https://doi.org/10.3390/molecules22050771
  6. Jiang Z, Gao W, Huang L. Tanshinones, critical pharmacological components in Salvia miltiorrhiza. Front Pharmacol 2019;10:202. https://doi.org/10.3389/fphar.2019.00202
  7. Wang J, Lin L, Li B, Zhang F, Liu N. Dietary Artemisia vulgaris meal improved growth performance, gut microbes, and immunity of growing Rex rabbits. Czech J Anim Sci 2019;64:174-9. https://doi.org/10.17221/162/2018-CJAS
  8. Ding K, Wang J, Liu N, Zhang F. Effect of Artemisia apiacea Hance on growth performance, cecal opportunistic bacteria, and microbicidal peptides in rabbits. R Bras Zootec 2019;48:e20190118. https://doi.org/10.1590/rbz4820190118
  9. Zhao H, Zhang F, Chai J, Wang J. Effect of lactic acid bacteria on Listeria monocytogenes infection and innate immunity in rabbits. Czech J Anim Sci 2020;65:23-30. https://doi.org/10.17221/247/2019-CJAS
  10. Zhao H, Zhang F, Chai J, Wang J. Lactobacillus acidophilus reduces Listeria monocytogenes infection by inhibiting mitogenactivated protein kinase genes in growing rabbits. R Bras Zootec 2020;49:e20200054. https://doi.org/10.37496/rbz4920200054
  11. Liu N, Wang JQ, Gu KT, Deng Q, Wang JP. Effects of dietary protein levels and multienzyme supplementation on growth performance and markers of gut health of broilers fed a miscellaneous meal based diet. Anim Feed Sci Technol 2017; 234:110-7. https://doi.org/10.1016/j.anifeedsci.2017.09.013
  12. Liu N, Wang JQ, Jia S, Chen Y, Wang JP. Effect of yeast cell wall on the growth performance and gut health of broilers challenged with aflatoxin B1 and necrotic enteritis. Poult Sci 2018;97:477-84. https://doi.org/10.3382/ps/pex342
  13. Abdallah A, Zhang P, Zhong Q, Sun Z. Application of traditional Chinese herbal medicine by-products as dietary feed supplements and antibiotic replacements in animal production. Curr Drug Metab 2019;20:54-64. https://doi.org/10.2174/1389200219666180523102920
  14. Hu G, Song Y, Ke S, et al. Tanshinone IIA protects against pulmonary arterial hypertension in broilers. Poult Sci 2017;96:1132-8. https://doi.org/10.3382/ps/pew322
  15. Yang CW, Ding X, Zhao X, Guo YX, Mu AL, Yang ZB. Effects of star anise (Illicium verum Hook. f.), salvia miltiorrhiza (Salvia miltiorrhiza Bge) and ginger root (Zingiber officinale Roscoe) on laying performance, antioxidant status and egg quality of laying hens. Eur Poult Sci 2017;81:183. https://doi.org/10.1399/eps.2017.183
  16. Li L, Li R, Zhu R, et al. Salvianolic acid B prevents body weight gain and regulates gut microbiota and LPS/TLR4 signaling pathway in high-fat diet-induced obese mice. Food Funct 2020;11:8743-56. https://doi.org/10.1039/d0fo01116a
  17. Chen X, Wu R, Kong Y, et al. Tanshinone II aattenuates renal damage in STZ-induced diabetic rats via inhibiting oxidative stress and inflammation. Oncotarget 2017;8:31915-22. https://doi.org/10.18632/oncotarget.16651
  18. Kong XF, Wu GY, Yin YL. Roles of phytochemicals in amino acid nutrition. Front Biosci 2011;3:372-84. https://doi.org/10.2741/s157
  19. Wang K, Yang Q, Ma Q, et al. Protective effects of salvianolic acid A against dextran sodium sulfate-induced acute colitis in rats. Nutrients 2018;10:791. https://doi.org/10.3390/nu10060791
  20. Cai H, Su S, Li Y, et al. Danshen can interact with intestinal bacteria from normal and chronic renal failure rats. Biomed Pharmacother 2019;109:1758-71. https://doi.org/10.1016/j.biopha.2018.11.047
  21. Asghari B, Salehi P, Sonboli A, Ebrahimi SN. Flavonoids from Salvia chloroleuca with α-amylsae and α-glucosidase inhibitory effect. Iran J Pharm Res 2015;14:609-15.
  22. Marrelli M, Grande F, Occhiuzzi MA, Maione F, Mascolo N, Conforti F. Cryptotanshinone and tanshinone IIA from Salvia milthorrhiza Bunge (Danshen) as a new class of potential pancreatic lipase inhibitors. Nat Prod Res 2021;35:863-6. https://doi.org/10.1080/14786419.2019.1607337
  23. Kasabri V, Afifi FU, Abu-Dahab R, et al. In vitro modulation of metabolic syndrome enzymes and proliferation of obesity related-colorectal cancer cell line panel by Salvia species from Jordan. Rev Roum Chim 2014;59:693-705.
  24. Liu N, Ding K, Wang JQ, Jia SC, Wang JP, Xu TS. Detoxification, metabolism, and glutathione pathway activity of aflatoxin B1 by dietary lactic acid bacteria in broiler chickens. J Anim Sci 2017;95:4399-406. https://doi.org/10.2527/jas2017.1644
  25. Liu N, Deng X, Liang C, Cai H. Effect of broccoli residues fermented with probiotics on the growth performance and health status of broilers challenged with Clostridium perfringens. Braz J Poult Sci 2018;20:625-32. https://doi.org/10.1590/1806-9061-2018-0741
  26. Wang J, Lin L, Jiang Q, Huang WL, Liu N. Probiotics and clay detoxifier protected growth performance and intestinal barrier of lambs fed diet contaminated with aflatoxin B1. Indian J Anim Sci 2019;89:658-62.
  27. Shi H, Shi H, Li Y, Liu N. Effect of lactic acid bacteria on growth performance, oxidative status and infectious parameters induced by Listeria monocytogenes in broilers. Eur Poult Sci 2020;84:316. https://doi.org/10.1399/eps.2020.316