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쌀겨오일의 안티폴루션 화장품 소재로써의 응용

Application of Oryza sativa (Rice) Bran Oil as an Anti-pollution Cosmetic Material

  • 강해란 (아주대학교 응용생명공학과) ;
  • 정소영 (아주대학교 응용생명공학과) ;
  • 허효진 (아주대학교 응용생명공학과) ;
  • 차병선 (아주대학교 응용생명공학과) ;
  • ;
  • 이소민 (아주대학교 응용생명공학과) ;
  • 여혜림 (아주대학교 응용생명공학과) ;
  • 유경완 (아주대학교 응용생명공학과) ;
  • 곽준수 (아주대학교 응용생명공학과) ;
  • 곽병문 (세명대학교 화장품뷰티생명공학부) ;
  • 이미기 (경기도경제과학진흥원) ;
  • 빈범호 (아주대학교 응용생명공학과)
  • Kang, Hae-Ran (Department of Applied Biotechnology, Ajou University) ;
  • Jung, So Young (Department of Applied Biotechnology, Ajou University) ;
  • Heo, Hyojin (Department of Applied Biotechnology, Ajou University) ;
  • Cha, Byungsun (Department of Applied Biotechnology, Ajou University) ;
  • Brito, Sofia (Department of Applied Biotechnology, Ajou University) ;
  • Lee, So Min (Department of Applied Biotechnology, Ajou University) ;
  • Yeo, Hye Lim (Department of Applied Biotechnology, Ajou University) ;
  • Yoo, Kyung Wan (Department of Applied Biotechnology, Ajou University) ;
  • Kwak, Jun Soo (Department of Applied Biotechnology, Ajou University) ;
  • Kwak, Byeong-Mun (Shool of Cosmetic Science and Beauty Biotechnology, Semyung University) ;
  • Lee, Mi-Gi (GBSA, Gyeonggido Business and Science Accelerator) ;
  • Bin, Bum-Ho (Department of Applied Biotechnology, Ajou University)
  • 투고 : 2021.08.27
  • 심사 : 2021.09.28
  • 발행 : 2021.09.30

초록

미세먼지와 초미세먼지는 일반적으로 사람 머리카락의 두께에 비하여 각각 1/6 ~ 1/7, 1/20 ~ 1/30 정도로 매우 작은 부유성 먼지를 뜻하며, 다양한 종류의 중금속 이온이 내포되어 있다. 호흡뿐 아니라 피부의 모공 틈새를 통해서 유입된 미세먼지는 체내 조직과 피부 건강에 문제를 유발할 수 있기 때문에 유입을 막거나 깨끗이 씻어내어 제거해야 한다. 본 연구를 통해 Oryza sativa (Rice) bran oil (OSBO, 쌀겨오일)을 이용하면 중금속 이온을 흡착하여 제거할 수 있을 것이라는 가능성을 확인하였다. 또한, 세포독성 실험을 통해 세포 생존율이 곡물 유래 성분과 비교했을 때에도 월등히 높아 외부 자극원에 대한 세포 보호 효과를 기대할 수 있다. COL1A1 mRNA의 발현량이 높아짐을 확인하였고, 이에 따라 미세먼지 속 중금속 이온에 의해 손실된 수분으로 유발될 수 있는 주름을 완화할 수 있을 것으로 사료된다. 이러한 실험 결과를 바탕으로 최종적으로 중금속 제거를 위한 워시-오프 제형의 OSBO 함유 화장품을 제시하고자 하였다.

Particulate matter and ultra-particle matters generally refer to very small floating dust, such as 1/6 to 1/7 and 1/20 to 1/30, respectively, compared to the thickness of human hair, and contain various types of heavy metal ions. In addition to breathing, particle matters (PM) that flows in through the gaps in the pores of the skin can induce health problems in the body's tissues and skin, so it must be removed by blocking the inflow or by washing. Through this study, we confirmed the possibility that heavy metal ions can be adsorbed and removed by using Oryza sativa (Rice) bran oil (OSBO). In addition, the cell viability is much higher than that of grain-derived components through cytotoxicity experiments, and the cytoprotective effect of an external stimulus source can be expected. It was confirmed that the expression amount of COL1A1 mRNA increased, and accordingly, it was believed that wrinkles that might be caused by moisture lost by heavy metal ions in fine dust could be alleviated. Based on the results of these experiments, we tried to present a cosmetics containing OSBO, which is a wash-off formulation, in order to finally remove heavy metals.

키워드

참고문헌

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