Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Intravoxel Incoherent Motion Magnetic Resonance Imaging for Assessing Parotid Gland Tumors: Correlation and Comparison with Arterial Spin Labeling Imaging

  • Gao Ma (Department of Radiology, The First Affiliated Hospital of Nanjing Medical University) ;
  • Xiao-Quan Xu (Department of Radiology, The First Affiliated Hospital of Nanjing Medical University) ;
  • Liu-Ning Zhu (Department of Stomatology, The First Affiliated Hospital of Nanjing Medical University) ;
  • Jia-Suo Jiang (Department of Radiology, The First Affiliated Hospital of Nanjing Medical University) ;
  • Guo-Yi Su (Department of Radiology, The First Affiliated Hospital of Nanjing Medical University) ;
  • Hao Hu (Department of Radiology, The First Affiliated Hospital of Nanjing Medical University) ;
  • Shou-Shan Bu (Department of Stomatology, The First Affiliated Hospital of Nanjing Medical University) ;
  • Fei-Yun Wu (Department of Radiology, The First Affiliated Hospital of Nanjing Medical University)
  • Received : 2020.01.11
  • Accepted : 2020.06.06
  • Published : 2021.02.01
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Abstract

Objective: To compare and correlate the findings of intravoxel incoherent motion (IVIM) magnetic resonance (MR) imaging and arterial spin labeling (ASL) imaging in characterizing parotid gland tumors. Materials and Methods: We retrospectively reviewed 56 patients with parotid gland tumors evaluated by MR imaging. The true diffusion coefficient (D), pseudo-diffusion coefficient (D*), and fraction of perfusion (f) values of IVIM imaging and tumor-to-parotid gland signal intensity ratio (SIR) on ASL imaging were calculated. Spearman rank correlation coefficient, chi-squared, Mann-Whitney U, and Kruskal-Wallis tests with the post-hoc Dunn-Bonferroni method and receiver operating characteristic curve assessments were used for statistical analysis. Results: Malignant parotid gland tumors showed significantly lower D than benign tumors (p = 0.019). Within subgroup analyses, pleomorphic adenomas (PAs) showed significantly higher D than malignant tumors (MTs) and Warthin's tumors (WTs) (p < 0.001). The D* of WTs was significantly higher than that of PAs (p = 0.031). The f and SIR on ASL imaging of WTs were significantly higher than those of MTs and PAs (p < 0.05). Significantly positive correlation was found between SIR on ASL imaging and f (r = 0.446, p = 0.001). In comparison with f, SIR on ASL imaging showed a higher area under curve (0.853 vs. 0.891) in discriminating MTs from WTs, although the difference was not significant (p = 0.720). Conclusion: IVIM and ASL imaging could help differentiate parotid gland tumors. SIR on ASL imaging showed a significantly positive correlation with f. ASL imaging might hold potential to improve the ability to discriminate MTs from WTs.

Keywords

References

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