Applied Chemistry for Engineering (공업화학)

The Korean Society of Industrial and Engineering Chemistry (한국공업화학회)
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Recent Research Trend of Biosensors for Colorectal Cancer Specific Protein Biomarkers

대장암 진단용 단백질 바이오마커 측정을 위한 바이오센서 개발의 최신 연구 동향

  • Li, Jingjing (Department of Chemistry, Kyungpook National University) ;
  • Si, Yunpei (Department of Chemistry, Kyungpook National University) ;
  • Lee, Hye Jin (Department of Chemistry, Kyungpook National University)
  • 리징징 (경북대학교 자연과학대학 화학과) ;
  • 스윈페이 (경북대학교 자연과학대학 화학과) ;
  • 이혜진 (경북대학교 자연과학대학 화학과)
  • Received : 2021.04.30
  • Accepted : 2021.05.20
  • Published : 2021.06.10
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Abstract

Colorectal cancer (CRC) is one of the most prevalent diseases in modern society, constituting a serious threat to global health. Currently, routine clinical screening and early removal of precancerous polyps are the most successful methods for reducing CRC incidence and mortality. However, the high cost and invasive detection of sigmoidoscopy and colonoscopy limited the CRC-screening participation and prevention. The emergence of biosensors provides an inexpensive, sensitive, less invasive tool for detecting CRC disease biomarkers. This review highlights some of recent efforts made on developing biosensors with electrochemical and optical techniques targeting CRC specific protein biomarkers for early diagnosis and prognosis, potential applications, and future perspectives.

Keywords

Acknowledgement

This research was supported by Kyungpook National University Development Project Research Fund, 2018.

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