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Fabrication and evaluation of hydrophobic metal stent using electron beam equipment

전자빔 처리를 통한 발수성 금속 스텐트 제작 및 평가

  • Kim, Jisoo (Department of Precision Mechanical Engineering, Kyungpook National University) ;
  • Park, Jongsung (Department of Precision Mechanical Engineering, Kyungpook National University)
  • 김지수 (경북대학교 정밀기계공학과) ;
  • 박종성 (경북대학교 정밀기계공학과)
  • Received : 2021.05.12
  • Accepted : 2021.05.24
  • Published : 2021.05.31

Abstract

The objective of this study was to fabricate a novel hydrophobic stent for reducing restenosis by employing electron beam equipment. The stent was fabricated from a CoCr alloy tube by using a femtosecond laser and was treated with argon plasma. Subsequently, the stent's surface specification changed from hydrophilic to hydrophobic. Application of the electron beam offers several advantages such as a short processing time, whole surface reforming, and enhancement of material properties. As the surface of the stent was rendered hydrophobic, it can provide equivalent or enhanced mechanical properties and greater functionality with a higher radial force at the extended stent in a blood vessel. The obtained results corresponding to the mechanical properties indicate that the contact angle increased to approximately 130°, and the radial force increased to approximately 3 N. Furthermore, cell culture experiments were conducted for verifying whether cells were cultured on the surface-modified CoCr surface. Based on the obtained results, it is believed that an effective reduction in the restenosis of inserted vascular stents is possible.

Keywords

Acknowledgement

본 연구는 한국연구재단 기본연구 지원 (2020R1F1A1074748, 2020R1F1A1071775)을 받아 수행 되었으며, 본 연구에 금속 스텐트 제작에 도움을 주신 전남대학교 의과대학 심혈관계융합센터 정명호 교수님과 연구팀, CG바이오에 감사의 말씀 올립니다.

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