DOI QR코드

DOI QR Code

연복자 추출물의 Phenolic acids와 Flavonoids의 조성 및 화장품 항산화 활성

Composition of Phenolic Acids and Flavonoids and Skin Care Cosmetic Antioxidant Activity of Akebia quinata Fruit Extracts

  • 장아람 (서경대학교 뷰티테라피&메이크업학과)
  • Jang, Ah-Ram (Deptartment of Beauty therapy & Makeup, Seokyeong University)
  • 투고 : 2021.03.12
  • 심사 : 2021.04.20
  • 발행 : 2021.04.28

초록

이 연구는 연복자의 열수와 80% 메탄올 추출물에 대한 총 polyphenol과 flavonoid의 함량과phenolic acid와 flavonoid의 조성 및 함량을 분석하고, 이 추출물에 대한 일부 항산화 활성을 조사하므로 스킨케어 기능성 화장품으로의 활용 가능성을 확인하는 것이 연구의 목적이다. 총 polyphenol과 flavonoid 함량은 열수와 80% 메탄올 추출물 모두에서 과피 추출물이 씨앗 추출물 보다 높은 것으로 나타났다. Phenolic acid는 열수 추출물에서 2종, 80% 메탄올 추출물에서 6종이 확인되었다. Flavonoids는 열수 추출물에서는 확인되지 않았으나, 80% 메탄올 추출물에서는 1종이 확인되었다. 또한 연복자의 열수와 80% 메탄올 추출물에 대한 항산화 활성을 조사한 결과, DPPH와 ABTS의 라디칼 소거능은 처리농도에 비례하여 증가하는 경향을 나타내어 항산화 활성이 높은 것으로 나타났다. 따라서 이와 같은 결과를 종합하여 보았을 때 연복자의 열수와 80% 메탄올 추출물은 항산화 활성을 나타내는 물질을 함유하고 있고, 항산화 활성이 확인되어 피부관리를 위한 기능성 화장품 성분원료 및 천연 항산화제로서의 가능성이 있을 것으로 사료되어진다.

In order to verify the effect of using functional cosmetic ingredients for skin beauty, the composition and content of some phenolic acid and flavonoids in the hot water and 80% methanol extract of Akebia quinata fruit pericarp and seeds were analyzed, and the skin care antioxidant activity was investigated. The results are as follows. Total polyphenol and flavonoid contents were found to be higher in pericarp extract than seed extract in both hot water and 80% methanol extract. In the analysis of the composition and content of phenolic acid and flavonoids, two kinds of phenolic acids were identified in the hot water extract of pericarp, 6 kinds of phenolic acids were identified in the 80% methanol extract, and one kind of flavonoid. Two types of phenolic acids were identified in the hot water and 80% methanol extract of seeds, respectively. DPPH and ABTS radical scavenging activities tended to increase in proportion to the treatment concentration in both hot water and 80% methanol extracts, and antioxidant activity was found to be high. Therefore, from the above results, it was found that the hot water and 80% methanol extract of Akebia quinata fruit pericarp and seeds contained various kinds of phenolic acid and flavonoids, and the antioxidant activity was also high. It is believed to be of value as a natural antioxidant in skin care cosmetic ingredients.

키워드

참고문헌

  1. Myung, K. B. (1992). Patch test in cosmetic contact dermatitis. The Ewha Medical Journal, 15(3), 217-222. DOI : 10.12771/emj.1992.15.3.217
  2. Eun, H. C., & Lee, D. Y. (1997). A study of cosmetic allergy in male patients. Korean Journal of Allergy, 17(1), 18-24.
  3. Nam, C. O., Song, Y. S., & Lee, K. K. (2016). A study on side effects on human health according to hair dyeing of hair beauty salon customers. Journal of the Korean society of beauty cultural arts, 4(1), 54-62.
  4. Halliwell, B., Hoult, J. R., & Blake, D. R. (1988). Oxidants, inflammation, and anti-inflammatory drugs. The FASEB journal, 2(13), 2867-2873. DOI : 10.1096/fasebj.2.13.2844616
  5. Kim, M. K. Lee, K. K., & Jang, A. R. (2011). A study on cosmetic physiological activities of Sasa borealis root extracts. Journal of the Korean Society of Cosmetology, 17(6), 1172-1177.
  6. Xia, W., Liu, P., Zhang, J., & Chen, J. (2011). Biological activities of chitosan and chitooligosaccharides. Food hydrocolloids, 25(2), 170-179. DOI : 10.1016/j.foodhyd.2010.03.003
  7. Antignac, E., Nohynek, G. J., Re, T., Clouzeau, J., & Toutain, H. (2011). Safety of botanical ingredients in personal care products/cosmetics. Food and Chemical Toxicology, 49(2), 324-341. DOI : 10.1016/j.fct.2010.11.022
  8. Park, K. N., Jeong, E. J., & Lee, S. H. (2007). Antimicrobial activity of turmeric(Curcuma aromatica Salab.) extracts against various pathogens and spoilage bacteria isolated from tofu. Korean Journal of Food Preservation, 14(2), 207-212.
  9. Kim, B. K., Choi, M. J., Park, K. Y., & Cho, E. J. (2010). Protective effects of Korean mistletoe lectin on radical-induced oxidative stress. Biological and Pharmaceutical Bulletin, 33(7), 1152-1158. DOI : 10.1248/bpb.33.1152
  10. You, D. H., Park, J. W., Yuk, H. G., & Lee, S. C. (2011). Antioxidant and tyrosinase inhibitory activities of different parts of guava(Psidium guajava L.). Food Science and Biotechnology, 20(4), 1095. DOI : 10.1007/s10068-011-0148-9
  11. Lee, Y. K., Song, Y. S., & Lee, K. K. (2012). Evaluation of antioxidant, tyrosinase inhibitory and anti-inflammatory activities of turmeric (Curcuma longa) extracts. International Journal of Beauty Cultural Arts, 1(1), 2-8.
  12. Jang, A. R., Song, Y. S., Kim, M. K., & Lee, K. K. (2015). Evaluation on the phenolic acid compositions and possibility of functional cosmetic ingredients of Hibiscus syriacus Bark extracts. Journal of the Korean Society of Cosmetology, 21, 895-902.
  13. Choi, J., Jung, H. J., Lee, K. T., & Park, H. J. (2005). Anti-oxidative and anti-inflammatory effects of the saponin and sapogenins obtained from the stem of Akebia quinata. Journal of medicinal food, 8(1), 78-85. DOI : 10.1089/jmf.2005.8.78
  14. Lee, G. D., Kwon, Y. R., Lee, Y. S., Jeon, J. G., Han, S. K., & Chang, K. W. (2008). Inhibitory effects of Akebia quinata fruit extract against mutans streptococci. Journal of Korean Academic. Dental Health, 32, 485-494.
  15. Ikuta, A., & Itokawa, H. (1988). A triterpene from Akebia quinata callus tissue. Phytochemistry, 27(12), 3809-3810. DOI : 10.1016/0031-9422(88)83022-X
  16. Rim, A. R., Kim, S. J., Jeon, K. I., Park, E. J., Park, H. R., & Lee, S. C. (2006). Antioxidant activity of extracts from Akebia quinata Decne. Preventive Nutrition and Food Science, 11(1), 84-87. DOI : 10.3746/jfn.2006.11.1.084
  17. Lee, S. H., Song, Y. S., Lee, S. Y., Kim, S. Y., & Ko, K. S. (2014). Protective effects of Akebia quinata fruit extract on acute alcohol-induced hepatotoxicity in mice. Korean Journal of Food Science and Technology, 46(5), 622-629. DOI : 10.9721/KJFST.2014.46.5.622
  18. Kim, J. W., & Youn, K. S. (2013). Effects of ripeness degree on the physicochemical properties and antioxidative activity of banana. Korean Journal of Food Preservation, 20(4), 475-481. DOI : 10.11002/kjfp.2013.20.4.475
  19. Higuchi, R., & Kawasaki, T. (1976). Pericarp saponins of Akebia quinata Decne. I. Glycosides of hederagenin and oleanolic acid. Chemical and Pharmaceutical Bulletin, 24(5), 1021-1032. DOI : 10.1248/cpb.24.1021
  20. Kim, M. H., & Choe, T. B. (2015). Anti-oxidant Activity of Akebia quinata fruit extract and the Effects of Skin. Journal of the Korean Applied Science and Technology, 32(3), 439-450. DOI : 10.12925/jkocs.2015.32.3.439
  21. Park, G. H. (2007). Antioxidant and anticancer effects of Akedia quinata. Master's dissertation. Inje University, Gimhae.
  22. Kim, J. S., Kim, J. Y., Kim, G. C., Kim, K. M., & Kang, M. H. (2013). Quality characteristics and antioxidant properties of saccharified banana gruels. Journal of the Korean Society of Food Science and Nutrition, 42(7), 1071-1078. DOI : 10.3746/jkfn.2013.42.7.1071