대한한방소아과학회지 (The Journal of Pediatrics of Korean Medicine)

  • 제35권1호
  • /
  • Pages.48-62
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  • 2021
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  • 1226-8038(pISSN)
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  • 2287-9463(eISSN)
대한한방소아과학회 (The Association of Korean Oriental Pediatrics)
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중의학 데이터베이스 (CAJ)를 이용한 급성백혈병의 한약치료에 대한 임상 연구 동향

Review of Clinical Studies for Herbal Medicine Treatment on Acute Leukemia - Focusing on Studies from the China Academic Journal (CAJ) -

  • 김정은 (부산대학교 한의학전문대학원) ;
  • 장진우 (부산대학교 한의학전문대학원) ;
  • 박범찬 (부산대학교 한의학전문대학원) ;
  • 김기봉 (부산대학교 한의학전문대학원) ;
  • 천진홍 (부산대학교 한의학전문대학원)
  • Kim, Jeong Eun (School of Korean Medicine, Pusan National University) ;
  • Jang, Jin Woo (School of Korean Medicine, Pusan National University) ;
  • Park, Beom Chan (School of Korean Medicine, Pusan National University) ;
  • Kim, Ki Bong (School of Korean Medicine, Pusan National University) ;
  • Cheon, Jin Hong (School of Korean Medicine, Pusan National University)
  • 투고 : 2020.12.30
  • 심사 : 2021.02.22
  • 발행 : 2021.02.28
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초록

Objectives The purpose of this study is to obtain knowledge from clinical studies conducted in China to examine the effectiveness of herb medicine in childhood acute leukemia. Methods We searched the randomized controlled trials (RCTs) with herbal medicine treatment on childhood acute leukemia from the 'CAJ', Chinese Academic Journal from China National Knowledge Infrastructure (CNKI). And then, demographic data, duration of illness, intervention, treatment period, outcome, adverse events, and composition of herbal medicine were analyzed for this study. Result 10 RCT studies were selected and analyzed. The control group were given western medicine therapy, the treatment group was given herbal medicine on the basis of the control group. The most commonly used herbal medicine were 淸熱解毒藥, 補氣藥, 補陰藥, 活血祛瘀藥 in 'boosting vital force and driving out evil spirit (扶正祛邪)' way to 'relieve heat (熱毒)' and 'assist the vital force (正氣)'. In the treatment group, complete remission was significantly higher than control group and the decrease in TCM syndrome scores also showed significant effects. Adverse events were significantly lower in the treatment group. Conclusions Herbal medicine treatment on childhood acute leukemia can be suggested as a new treatment for children who have less response to the conventional therapy, and can supplement the limitations of the western medicine by increasing complete remission and reducing adverse events.

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