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콩깍지 추출물의 항산화·항염·항비만 및 에스트로겐 유사활성 평가

Antioxidant, Anti-inflammatory, Anti-obesity and Estrogen-like Activities of Soybean Pod Extracts

  • 정은숙 (국립농업과학원 농식품자원부) ;
  • 김행란 (국립농업과학원 농식품자원부) ;
  • 황유진 (국립농업과학원 농식품자원부) ;
  • 장경아 (국립농업과학원 농식품자원부) ;
  • 서미경 (국립농업과학원 농식품자원부) ;
  • 추한나 (국립농업과학원 농식품자원부)
  • Jung, Eun-Suk (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA) ;
  • Kim, Haeng-Ran (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA) ;
  • Hwang, Yu-Jin (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA) ;
  • Jang, Kyeong-A (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA) ;
  • Seo, Mi-Kyung (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA) ;
  • Chu, Han-na (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA)
  • 투고 : 2021.11.11
  • 심사 : 2021.12.19
  • 발행 : 2021.12.31

초록

In this study, soybean pods of 45 soybean landraces (or varieties) were classified as yellow (19 samples), black (23 samples), or black in green (3 samples) based on soybean seed coat color. Total polyphenol and flavonoid contents were measured, and antioxidant, anti-inflammatory, anti-obesity, and estrogen-like activities were assessed. Total polyphenol and flavonoid content ranges were 24.13-108.03 mg GAE/g and 3.31-72.02 mg CE/g, respectively, and were highest in the black group followed by the yellow group and were least in the black in green group, while ABTS and DPPH activities followed the order black in green > black > yellow. Estrogen-like and estrogen receptor-α activity ranges were 29.06-35.58 pg/mL and 7.05-10.13 pg/mL and were followed the order yellow > black > black in green and black in green > yellow > black, respectively. Nitric oxide (NO) inhibitory and UCP-1 activities followed the same order as estrogen receptor-α activities. Our findings suggest that soybean pods are excellent sources of antioxidants and high-quality functional materials.

키워드

과제정보

본 연구는 농촌진흥청 국립농업과학원 농식품자원연구(과제번호 PJ01417202)의 지원에 의하여 수행되었고, 이에 감사드립니다.

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