Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Clinical application of insect-based diet in canine allergic dermatitis

  • Lee, Kang-Il (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University) ;
  • Chae, Yeon (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University) ;
  • Yun, Taesik (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University) ;
  • Koo, Yoonhoi (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University) ;
  • Lee, Dohee (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University) ;
  • Kim, Hakhyun (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University) ;
  • So, Kyoung-Min (Division of Animal Diseases & Health, National Institute of Animal Science, Rural Development Administration) ;
  • Cho, Woo Jae (Veterinary Nutrition Laboratory, JEIL. FEED. Co. Ltd) ;
  • Kim, Ha-Jung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University) ;
  • Yang, Mhan-Pyo (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University) ;
  • Kang, Byeong-Teck (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University)
  • Received : 2021.07.07
  • Accepted : 2021.10.02
  • Published : 2021.12.31
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Abstract

The objective of this study was to evaluate the beneficial effects of the short-term application of insect-based diet in canine allergic dermatitis. Total 19 atopic dogs with concurrent cutaneous adverse food reactions were enrolled and classified into 3 groups. The treatment group (n = 7) was fed insect-based diet, the positive control group (n = 6) was fed salmon-based diet, and the negative control group (n = 6) was fed commercial or homemade diet for 12 weeks. The degree of skin lesions was evaluated based on canine atopic dermatitis extent and severity index (CADESI-4). Additionally, transepidermal water loss (TEWL) and pruritus visual analog scale were evaluated. All indices were evaluated every 4 weeks after the initial administration of hypoallergenic diets. In the treatment group, significant decrease in the CADESI-4 score was observed at 8 weeks compared to the baseline score (p = 0.031). There were significant differences in the CADESI-4 score between the groups at 8 weeks (p = 0.008), 12 weeks (p = 0.012), and TEWL at 12 weeks (p = 0.022). This preliminary result demonstrates the potential hypoallergenicity of an insect-based diet through features that diminish cutaneous lesions and skin barrier dysfunction.

Keywords

Acknowledgement

This work was carried out with the support of "Cooperative Research Program for Agriculture Science and Technology Development (Project No: PJ01283408)" Rural Development Administration, Republic of Korea.

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