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수부냉증 진단을 위한 조갑모세혈관 혈류속도 측정 예비연구

The Role of Nail-fold Capillary Blood Velocity in Evaluating Cold Hypersensitivity in the Hands: A Pilot Study

  • 안일구 (한국한의학연구원 한의약 데이터부) ;
  • 박기현 (한국한의학연구원 한의약 데이터부) ;
  • 이시우 (한국한의학연구원 한의약 데이터부) ;
  • 정경식 (한국한의학연구원 한의약 데이터부) ;
  • 배지용 (세명대학교 한의과대학 한방내과) ;
  • 권정연 (세명대학교 한의과대학 한방내과) ;
  • 공경환 (세명대학교 한의과대학 한방내과) ;
  • 고호연 (세명대학교 한의과대학 한방내과) ;
  • 배광호 (한국한의학연구원 한의약 데이터부)
  • Ahn, Ilkoo (KM Data Division, Korea Institute of Oriental Medicine) ;
  • Park, Ki-Hyun (KM Data Division, Korea Institute of Oriental Medicine) ;
  • Lee, Siwoo (KM Data Division, Korea Institute of Oriental Medicine) ;
  • Jeong, Kyoungsik (KM Data Division, Korea Institute of Oriental Medicine) ;
  • Bae, Ji-yong (Department of Internal Medicine, College of Korean Medicine, Semyung University) ;
  • Kwon, Jung-yeon (Department of Internal Medicine, College of Korean Medicine, Semyung University) ;
  • Kong, Kyung-hwan (Department of Internal Medicine, College of Korean Medicine, Semyung University) ;
  • Go, Ho-yeon (Department of Internal Medicine, College of Korean Medicine, Semyung University) ;
  • Bae, Kwang-Ho (KM Data Division, Korea Institute of Oriental Medicine)
  • 투고 : 2021.07.22
  • 심사 : 2021.12.06
  • 발행 : 2021.12.25

초록

This study aims to compare nail-fold capillary blood velocity (CBV) according to the presence or absence of cold hypersensitivity in the hands (CHH) using nail-fold capillaroscopy under cold stress conditions. Eleven participants were taken from the cohort study for observing long-term health status of the faculty of Semyung university. Seven of the participants displayed CHH while four showed signs of non-CHH. CBV between 0 and 60 seconds (S1) and between 240 and 300 seconds (S2) was measured under cold stress for 5 minutes, respectively, and the average value was used to compare non-CHH group and CHH group. Body mass index, Nogung (PC8) temperature and temperature difference between Nogung (PC8) and Hyeopbaek (LU4) were significantly lower in CHH group compared to non-CHH group. The S2-S1 CBV difference was negatively correlated with PC8 temperature and PC8-LU4 temperature, and positively correlated with cold pattern score and cold hypersensitivity visual analog scale. The CHH group had a lower CBV overall than non-CHH group, and the S2-S1 CBV difference was significantly higher in the CHH group than in non-CHH group. This study suggests that CBV measured by nail-fold capillarosopy might be a useful indicator of cold hypersensitivity properties.

키워드

과제정보

본 연구는 2021년도 한국한의학연구원 기관주요사업인 "빅데이터 기반 한의 예방 치료 원천기술 개발"(Grant No. KSN2022120)의 지원을 받아 수행된 연구임.

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