References
- J. Greenwald and R. Riek, Biology of amyloid: Structure, function, and regulation, Structure, 18, 1244-1260 (2018). https://doi.org/10.1016/j.str.2010.08.009
- P. Faller, C. Hureau, and O. Berthoumieu, Role of metal ions in the self-assembly of the Alzheimer's amyloid-beta peptide, Inorg. Chem., 52, 12193-12206 (2013). https://doi.org/10.1021/ic4003059
- Y.-H. Suh and F. Checler, Amyloid precursor protein, presenilins, and α-synuclein: Molecular pathogenesis and pharmacological applications in Alzheimer's disease, Pharmacol. Res., 54, 469-525 (2002).
- U. C. Müller, T. Deller, and M. Korte, Not just amyloid: Phy- siological functions of the amyloid precursor protein family, Nat. Rev. Neurosci., 18, 281-298 (2017). https://doi.org/10.1038/nrn.2017.29
- K. P. Kepp, Bioinorganic chemistry of Alzheimer's disease, Chem. Rev., 112, 5193-5239 (2012). https://doi.org/10.1021/cr300009x
- K. Iqbal, A. del C. Alonso, S. Chen, M. O. Chohan, E. El-Akkad, C.-X. Gong, S. Khatoon, B. Li, F. Liu, A. Rahman, H. Tanimukai, and I. Grundke-Iqbal, Tau pathology in Alzheimer disease and other tauopathies, Biochim. Biophys. Acta, Mol. Basis Dis., 1739, 198-210 (2005). https://doi.org/10.1016/j.bbadis.2004.09.008
- K. V. Kuchibhotla, S. Wegmann, K. J. Kopeikina, J. Hawkes, N. Rudinskiy, M. L. Andermann, T. L. Spires-Jones, B. J. Bacskai, and B. T. Hyman, Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo, Proc. Natl. Acad. Sci. U. S. A., 111, 510-514 (2014). https://doi.org/10.1073/pnas.1318807111
- G. Lippens, A. Sillen, I. Landrieu, L. Amniai, N. Sibille, P. Barbier, A. Leroy, X. Hanoulle, and J.-M. Wieruszeski, Tau aggregation in Alzheimer's disease, Prion, 1, 21-25 (2007). https://doi.org/10.4161/pri.1.1.4055
- I. Grundke-Iqbal, K. Iqbal, Y. C. Tung, M. Quinlan, H. M. Wisniewski, and L. I. Binder, Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology, Proc. Natl. Acad. Sci. U. S. A., 83, 4913-4917 (1986). https://doi.org/10.1073/pnas.83.13.4913
- A. Lorenzo and B. A. Yankner, Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red, Proc. Natl. Acad. Sci. U. S. A., 91, 12243-12247 (1994). https://doi.org/10.1073/pnas.91.25.12243
- W. E. Klunk, M. L. Debnath, and J. W. Pettegrew, Chrysamine-G binding to Alzheimer and control brain: Autopsy study of a new amyloid probe, Neurobiol. Aging, 16, 541-548 (1995). https://doi.org/10.1016/0197-4580(95)00058-M
- H. Naiki, K. Higuchi, M. Hosokawa, and T. Takeda, Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavine T, Anal. Biochem., 177, 244-249 (1989). https://doi.org/10.1016/0003-2697(89)90046-8
- W. E. Klunk, B. J. Bacskai, C. A. Mathis, S. T. Kajdasz, M. E. McLellan, M. P. Frosch, M. L. Debnath, D. P. Holt, Y. Wang, and B. T. Hyman, Imaging Aβ plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered congo red derivative, J. Neuropathol. Exp. Neurol., 61, 797-805 (2002). https://doi.org/10.1093/jnen/61.9.797
- M. Hintersteiner, A. Enz, P. Frey, A.-L. Jaton, W. Kinzy, R. Kneuer, U. Neumann, M. Rudin, M. Staufenbiel, M. Stoeckli, K.-H. Wiederhold, and H.-U. Gremlich, In vivo detection of amyloid-β deposits by near-infrared imaging using an oxazine-derivative probe, Nat. Biotechnol., 23, 577-583 (2005). https://doi.org/10.1038/nbt1085
- A. G. Vlassenko, T. L. S. Benzinger, and J. C. Morris, PET amyloid-beta imaging in preclinical Alzheimer's disease, Biochim. Biophys. Acta, Mol. Basis Dis., 1822, 370-379 (2012). https://doi.org/10.1016/j.bbadis.2011.11.005
- C. A. Mathis, N. S. Mason, B. J. Lopresti, and W. E. Klunk, Development of positron emission tomography β-amyloid plaque imaging agents, Semin. Nucl. Med., 42, 423-432 (2012). https://doi.org/10.1053/j.semnuclmed.2012.07.001
- N. A. Murugan, R. Zalesny, J. Kongsted, A. Nordberg, and H. Agren, Promising two-photon probes for in vivo detection of β amyloid deposits, Chem. Commun., 50, 11694-11697 (2014). https://doi.org/10.1039/C4CC03897E
- P. Verwilst, H. S. Kim, S. Kim, C. Kang, and J. S. Kim, Shedding light on tau protein aggregation: the progress in developing highly selective fluorophores, Chem. Soc. Rev., 47, 2249-2265 (2018). https://doi.org/10.1039/C7CS00706J
- P. Verwilst, H.-R. Kim, J. Seo J, N.-W. Sohn, S.-Y. Cha, Y. Kim, S. Maeng, J.-W. Shin, J. H. Kwak C. Kang, and J. S. Kim, Rational design of in vivo tau tangle-selective near-infrared fluorophores: expanding the bodipy universe, J. Am. Chem. Soc., 139, 13393-13403 (2017). https://doi.org/10.1021/jacs.7b05878
- E. E. Nesterov, J. Skoch, B. T. Hyman, W. E. Klunk, B. J. Bacskai and T. M. Swager, In vivo optical imaging of amyloid aggregates in brain: Design of fluorescent markers, Angew. Chem. Int. Ed., 44, 5452-5456 (2008). https://doi.org/10.1002/anie.200500845
- S. B. Raymond, J. Skoch, I. D. Hills, E. E. Nesterov, T. M. Swager, and B. J. Bacskai, Smart optical probes for near-infrared fluorescence imaging of Alzheimer's disease pathology, Eur. J. Nucl. Med. Mol. Imaging, 35, 93-98 (2008). https://doi.org/10.1007/s00259-007-0708-7
- Y. Wang, T. Liu, E. Zhang, S. Luo, X. Tan, and C. Shi, Preferential accumulation of the near infrared heptamethine dye IR-780 in the mitochondria of drug-resistant lung cancer cells, Biomaterials, 35, 4116-4124 (2014). https://doi.org/10.1016/j.biomaterials.2014.01.061
- G. Lv, A. Sun, P. Wei, N. Zhang, H. Lan, and T. Yi, A spiropyran-based fluorescent probe for the specific detection of b-amyloid peptide oligomersin Alzheimer's disease, Chem. Commun., 52, 8865 (2016). https://doi.org/10.1039/C6CC02741E
- J. W. Yan, J. Y. Zhu, K. X. Zhou, J. S. Wang, H. Y. Tan, Z. Y. Xu, S. B. Chen, Y. T. Lu, M. C. Cui, and L. Zhang, Neutral merocyanine dyes: for in vivo NIR fluorescence imaging of amyloid-β plaques, Chem. Commun., 53, 9910-9913 (2017). https://doi.org/10.1039/C7CC05056A
- H. L. Yang, S. Q. Fang, Y. W. Tang, C. Wang, H. Luo, L. L. Qu, J. H. Zhao, C. J. Shi, F. C. Yin, X. B. Wang, and L. Y. Kong, A hemicyanine derivative for near-infrared imaging of betaamyloid plaques in Alzheimer's disease, Eur. J. Med. Chem., 179, 736-743 (2019). https://doi.org/10.1016/j.ejmech.2019.07.005
- H. Y. Kim, U. Sengupta, P. Shao, M. J. Guerrero-Munoz, R. Kayed, and M. Bai, Alzheimer's disease imaging with a novel Tau targeted near infrared ratiometric probe, Am. J. Nucl. Med. Mol. Imaging, 3, 102-117 (2013).
- S. Aggarwal, H. Ichikawa, Y. Takada, S. K. Sandur, S. Shishodia, and B. B. Aggarwal, Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IκBα kinase and Akt activation, Mol. Pharmacol., 69, 195-206 (2006). https://doi.org/10.1124/mol.105.017400
- C. Ran, X. Xu, S. B. Raymond, B. J. Ferrara, K. Neal, B. J. Bacskai, Z. Medarova, and A. Moore, Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits, J. Am. Chem. Soc., 131, 15257-15261 (2009). https://doi.org/10.1021/ja9047043
- X. Zhang, Y. Tian, Z. Li, X. Tian, H. Sun, H. Liu, A. Moore, and C. Ran, Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer's disease, J. Am. Chem. Soc., 135, 16397-16409 (2013). https://doi.org/10.1021/ja405239v
- X. Zhang, Y. Tian, C. Zhang, X. Tian, A. W. Ross, R. D. Moir, H. Sun, R. E. Tanzi, A. Moore, and C. Ran, Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease, Proc. Natl. Acad. Sci. U. S. A., 112, 9734-9739 (2015). https://doi.org/10.1073/pnas.1505420112
- Y. Li, J. Yang, H. Liu, J. Yang, L. Du, H. Feng, Y. Tian, J. Cao, and C. Ran, Tuning the stereo-hindrance of a curcumin scaffold for the selective imaging of the soluble forms of amyloid beta species, Chem. Sci., 8, 7710-7717 (2017). https://doi.org/10.1039/C7SC02050C
- K. S. Park, Y. Seo, M. K. Kim, K. Kim, Y. K. Kim, H. Choo, and Y. A. Chong, Curcumin-based molecular probe for near-infrared fluorescence imaging of tau fibrils in Alzheimer's disease, Org. Biomol. Chem., 13, 11194-11199 (2015). https://doi.org/10.1039/C5OB01847A
- Y. Seo, K. S. Park, T. Ha, M. K. Kim, Y. J. Hwang, J. Lee, H. Ryu, H. Choo, and Y. Chong, A smart near-infrared fluorescence probe for selective detection of tau fibrils in Alzheimer's disease, ACS Chem. Neurosci., 7, 1474-1481 (2016). https://doi.org/10.1021/acschemneuro.6b00174
- K. S. Park, K. Yoo, M. K. Kim, W. Jung, Y. K. Choi, and Y. Chong, A novel probe with a chlorinated α cyanoacetophenone acceptor moiety shows near-infrared fluorescence specific for tau fibrils, Chem. Pharm. Bull., 65, 1113-1116 (2017). https://doi.org/10.1248/cpb.c17-00559
- K.-S. Park, M. K. Kim, Y. Seo, T. Ha, K. Yoo, S. J. Hyeon, Y. J. Hwang, J. Lee, H. Ryu, H. Choo, and Y. A. Chong, Difluoroboron β-diketonate probe shows "Turn-on" near-infrared fluorescence specific for tau fibrils, ACS Chem. Neurosci., 8, 2124-2131 (2017). https://doi.org/10.1021/acschemneuro.7b00224
- A. Loudet and K. Burgess, BODIPY dyes and their derivatives: Syntheses and spectroscopic properties, Chem. Rev., 107, 4891-4932 (2007). https://doi.org/10.1021/cr078381n
- H. Watanabe, M. Ono, K. Matsumura, M. Yoshimura, H. Kimura, and H. Saji, Molecular imaging of ß-amyloid plaques with near-infrared boron dipyrromethane (BODIPY)-based fluorescent probes, Mol. Imaging, 12, 338-347 (2013).
- L. Teoh, D. Su, S. Sahu, S. W. Yun, E. Drummond, F. Prelli, S. Lim, S. Cho, S. Ham, T. Wisniewski, and Y. T. Chang, A chemical fluorescent probes for the detection of Aβ oligomers, J. Am. Chem. Soc., 137, 13503 (2015). https://doi.org/10.1021/jacs.5b06190
- W. Ren, J. Zhang, C. Peng, H. Xiang, J. Chen, C. Peng, W. Zhu, R. Huang, H. Zhang, and Y. Hu, Fluorescent imaging of beta-amyloid using BODIPY based near-infrared off-on fluorescent probe, Bioconjugate Chem., 29, 3459-3466 (2018). https://doi.org/10.1021/acs.bioconjchem.8b00623
- P. Verwilst, H.-R. Kim, J. Seo, N.-W. Sohn, S.-Y. Cha, Y. Kim, S. Maeng, J.-W. Shin, J. H. Kwak, C. Kang, and J. S. Kim, Rational design of in vivo tau tangle-selective near infrared fluorophores: Expanding the BODIPY universe, J. Am. Chem. Soc., 139, 13393-13403 (2017). https://doi.org/10.1021/jacs.7b05878
- W. Yang, Y. Wong, O. T. Ng, L. P. Bai, D. W. Kwong, Y. Ke, Z. H. Jiang, H. W. Li, K. K. Yung, and M. S. Wong, Inhibition of beta-amyloid peptide aggregation by multifunctionalcarbazole-based fluorophores, Angew. Chem. Int. Ed., 51, 1804-1810 (2012). https://doi.org/10.1002/anie.201104150
- Y. Li, D. Xu, S. L. Ho, H. W. Li, R. Yang, and M. S. Wong, A theranostic agent for in vivo near-infrared imaging of β-amyloid species and inhibition of β-amyloid aggregation, Biomaterials, 94, 84-92 (2016). https://doi.org/10.1016/j.biomaterials.2016.03.047