Journal of Wellbeing Management and Applied Psychology (웰빙융합연구)

Korea Wellbeing Convergence Association (한국웰빙융합학회)
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Improving the Skin Penetration of Cosmetics Containing Omega 3 Fatty Acids

  • KIM, Han-Sook (Department of Chemical Engineering & Biotechnology, Korea Polytechnic University) ;
  • HAN, Sien-Ho (Department of Chemical Engineering & Biotechnology, Korea Polytechnic University)
  • Received : 2021.12.21
  • Accepted : 2021.12.23
  • Published : 2021.12.31
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Abstract

Purpose: The purpose of this study is to form a new cosmetic market through the development of a composition with high skin permeability after adding omega 3 to Aloe Vera soothing gel products. Research design, data and methodology: In this study, omega-3 fatty acids were added to cosmetic products in the form of soothing gels. By applying nanoparticle technology to rapidly increase the penetration of raw materials into the skin, characteristics related to skin moisture and regeneration were determined. Omega-3 was used as a raw cosmetic material. Then 5% and 15% nanoparticle aqueous products containing omega-3 were prepared. The developed water hydrate was subjected to skin permeability test using artificial skin. Results: 53 hours of artificial transdermal penetration of the developed composition, the ethanol-based omega-3 containing nanoparticle solubilized raw material was about three times higher penetration than the ethanol-based omega-3 containing nanoparticle solubilized raw material. Conclusions: The raw material product (SR-1901) containing 5% of omega-3 nanoparticle water hydrate has skin regeneration ability and pain reduction effect. It can be expected that the skin cosmetics market will be reorganized into a new distribution structure and opportunity through omega-3 supplemented soothing gel cosmetics with improved efficacy than existing cosmetics.

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References

  1. Boudreau, M. D., & Beland, F. A. (2006). An evaluation of the biological and toxicological properties of Aloe barbadensis (miller), Aloe Vera. Journal of Environmental Science and Health, 24(1), 103-154. doi: 10.1080/10590500600614303
  2. Calder, P. C. (2013). n-3 fatty acids, inflammation and immunity: new mechanisms to explain old actions. Proceedings of the Nutrition Society, 72(3), 326-336. doi: 10.1017/S0029665113001031
  3. Connor, W. E. (2000). Importance of n-3 fatty acids in health and disease. American Journal of Clinical Nutrition, 71(1), 171S-175S. doi: 10.1093/ajcn/71.1.171S
  4. Dewailly, E., Blanchet, C., Lemieux, S., Sauve, L., Gingras, S., Ayotte, P., & Holub, B. F. (2001). n - 3 Fatty acids and cardiovascular disease risk factors among the Inuit of Nunavik. The American journal of clinical nutrition, 74(4), 464-473. doi: 10.1093/ajcn/74.4.464
  5. Dorni, A. C., Amalraj, A., Gopi, S., Varma, K., & Anjana, S. (2017). Novel cosmeceuticals from plants?An industry guided review. Journal of applied research on medicinal and aromatic plants, 7(December), 1-26. doi: 10.1016/j.jarmap.2017.05.003
  6. Draelos, Z. D. (2009). Cosmeceuticals: undefined, unclassified, and unregulated. Clinics in dermatology, 27(5), 431-434. https://doi.org/10.1016/j.clindermatol.2009.05.005
  7. Dyerberg, J., & Bang, H. (1979). Lipid metabolism, atherogenesis, and haemostasis in Eskimos: the role of the prostaglandin-3 family. Pathophysiology of Haemostasis and Thrombosis, 8(3-5), 227-233. doi: 10.1159/000214314
  8. Dyerberg, J., Bang, H., Stoffersen, E., Moncada, S., & Vane, J. (1978). Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis? The Lancet, 312(8081), 117-119. https://doi.org/10.1016/S0140-6736(78)91505-2
  9. Fodor, J. G., Helis, E., Yazdekhasti, N., & Vohnout, B. (2014). "Fishing" for the origins of the "Eskimos and heart disease" story: facts or wishful thinking? Canadian Journal of Cardiology, 30, 864-868. doi: 10.1016/j.cjca.2014.04.007
  10. Goede, J., Geleijnse, J. M., Boer, J. M., Kromhout, D., & Verschuren, W. M. (2010). Marine (n-3) fatty acids, fish consumption, and the 10-year risk of fatal and nonfatal coronary heart disease in a large population of Dutch adults with low fish intake. The Journal of Nutrition, 140(5), 1023-1028. doi: 10.3945/jn.109.119271
  11. Gupta, A., & Rawat, S. (2017). Clinical importance of aloe vera. Research Journal of Topical and Cosmetic Sciences, 8(1), 30-39. https://doi.org/10.5958/2321-5844.2017.00004.8
  12. Hankenson, K. D., Watkins, B. A., Schoenlein, I. A., Allen, K. G., & Turek, J. J. (2000). Omega-3 Fatty Acids Enhance Ligament Fibroblast Collagen Formation in Association with Changes in Interleukin-6 Production (44467). Proceedings of the Society for Experimental Biology and Medicine, 223(1), 88-95. doi: 10.1111/j.1525-1373.2000.22312.x
  13. Kuhnlein, H. V., Receveur, O., & Chan, H. (2001). Traditional food systems research with Canadian indigenous peoples. International Journal of Circumpolar Health, 60(2), 112-122.
  14. Larsson, S. C., Virtamo, J., & Wolk, A. (2011). Fish consumption and risk of stroke in Swedish women. The American Journal of Clinical Nutrition, 93(3), 487-493. doi: 10.3945/ajcn.110.002287
  15. Lintner, K., Mas-Chamberlin, C., Mondon, P., Peschard, O., & Lamy, L. (2009). Cosmeceuticals and active ingredients. Clinics in dermatology, 27(5), 461-468. https://doi.org/10.1016/j.clindermatol.2009.05.009
  16. Meguro, S., Arai, Y., Masukawa, Y., Uie, K., & Tokimitsu, I. (2000). Relationship between covalently bound ceramides and transepidermal water loss (TEWL). Archives of Dermatological Research, 292, 463-468. doi: 10.1007/s004030000160
  17. Mozaffarian, D., & Wu, J. Y. (2001). Omega-3 fatty acids and cardiovascular disease: Effects on risk factors, molecular pathways, and clinical events. Journal of the American College of Cardiology, 58(20), 2047-2067. doi: 10.1016/j.jacc.2011.06.063
  18. Newburger, A. E. (2009). Cosmeceuticals: myths and misconceptions. Clinics in dermatology, 27(5), 446-452. https://doi.org/10.1016/j.clindermatol.2009.05.008
  19. Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of traditional and complementary medicine, 5(1), 21-26. doi: 10.1016/j.jtcme.2014.10.006
  20. Serhan, C. N. (2014). Pro-resolving lipid mediators are leads for resolution physiology. Nature, 510, 92-101. doi: 10.1038/nature13479
  21. Serhan, C. N., Chiang, N., & Van Dyke, T. E. (2008). Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators. Nature Reviews Immunology, 8(5), 349-361. doi: 10.1038/nri2294
  22. Shi, X. D., Yin, J. Y., Huang, X. J., Que, Z. Q., & Nie, S. P. (2018). Structural and conformational characterization of linear Oacetyl-glucomannan purified from gel of Aloe barbadensis Miller. International journal of biological macromolecules, 120(8), 2373-2380. https://doi.org/10.1016/j.ijbiomac.2018.09.005
  23. Surjushe, A., Vasani, R., & Saple, D. (2008). Aloe Vera: a short review. Indian journal of dermatology, 53(4), 163-166. doi: 10.4103/0019-5154.44785
  24. Villani, A. M., Crotty, M., Cleland, L. G., James, M. J., Fraser, R. J., Cobiac, L., & Miller, M. D. (2013). Fish oil administration in older adults: is there potential for adverse events? A systematic review of the literature. BMC geriatrics, 13(1), 1-9. https://doi.org/10.1186/1471-2318-13-1
  25. Wu, D., Chen, X., Cao, F., Sun, D. W., He, Y., & Jiang, Y. (2014). Comparison of infrared spectroscopy and nuclear magnetic resonance techniques in tandem with multivariable selection for rapid determination of ω-3 polyunsaturated fatty acids in fish oil. Food and bioprocess technology, 7, 1555-1569. doi: 10.1007/s11947-013-1147-z