The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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A Case Report of Symptom Improvement in a Patient Diagnosed with Nontuberculous Mycobacterial Lung Disease Treated with Korean Medicine

비결핵 항산균 폐질환 환자의 한의치료로 증상 호전에 대한 증례보고

  • Kang, Sung-woo (Division of Allergy, Immune & Respiratory System, Dept. of Internal Medicine, Graduate School, Kyung Hee University) ;
  • Yu, Chang-hwan (Division of Allergy, Immune & Respiratory System, Dept. of Internal Medicine, Graduate School, Kyung Hee University) ;
  • Hong, Sung-eun (Division of Allergy, Immune & Respiratory System, Dept. of Internal Medicine, Graduate School, Kyung Hee University) ;
  • Kim, Dae-young (Division of Allergy, Immune & Respiratory System, Dept. of Internal Medicine, Graduate School, Kyung Hee University) ;
  • Kim, Kwan-il (Division of Allergy, Immune & Respiratory System, Dept. of Internal Medicine, Graduate School, Kyung Hee University) ;
  • Lee, Beom-joon (Division of Allergy, Immune & Respiratory System, Dept. of Internal Medicine, Graduate School, Kyung Hee University) ;
  • Jung, Hee-jae (Division of Allergy, Immune & Respiratory System, Dept. of Internal Medicine, Graduate School, Kyung Hee University)
  • 강성우 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 유창환 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 홍성은 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 김대영 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 김관일 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 이범준 (경희대학교 대학원 임상한의학과 폐계내과학교실) ;
  • 정희재 (경희대학교 대학원 임상한의학과 폐계내과학교실)
  • Received : 2020.09.11
  • Accepted : 2020.10.20
  • Published : 2020.10.30
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Abstract

Objectives: The purpose of this case study was to report the effect of Korean Medicine treatment on a patient diagnosed with nontuberculous mycobacterial lung disease. Methods: A 61-year-old female patient with nontuberculous mycobacterial lung disease was admitted to the clinic from October 15th, 2018 to November 7th, 2018. The patient was treated using Korean medical treatments of Jinhae-tang-gami, Ssanghwa-tang-gami, Haeyeol-tang, Jinhae-tang plus Ssanghwa-tang-gami, and Jinhae-tang plus Bojungikgi-tang-gami. We evaluated the improvement of symptoms by a numeric rating scale (NRS) score, C-reactive protein (CRP) levels, erythrocyte sedimentation rate (ESR), and body temperature. Results: After Korean medicine treatment, the patient's cough and sputum amounts were decreased as measured by the NRS score. CRP levels and ESR were also decreased and fever was relieved. Conclusion: This study suggested that Korean medicine treatment might be effective in treating patients diagnosed with nontuberculous mycobacterial lung disease.

Keywords

References

  1. Griffith DE, Aksamit T, Brown-Elliott BA, Catanzaro A, Daley C, Gordin F, et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med 2007;175(4):367-416. https://doi.org/10.1164/rccm.200604-571ST
  2. Kwon YS. Diagnosis and Treatment of Nontuberculous Mycobacterial Lung Disease. Korean J med 2012;82(3):274-83. https://doi.org/10.3904/kjm.2012.82.3.274
  3. Kim KI, Lee HB, Choi KH, Jung HJ, Jung SK. A clinical case treated with oriental medicine on one patient with nontuberculous mycobacterium lung disease. J Int Korean Med 2012;33(110):217-26.
  4. Yoon HJ, Choi HY, Ki M. Nontuberculosis mycobacterial infections at a specialized tuberculosis treatment centre in the Republic of Korea. BMC Infect Dis 2017;17(1):432. https://doi.org/10.1186/s12879-017-2532-4
  5. 전국한의과대학 폐계내과학교실. 폐계내과학. 서울: 도서출판 나도; 2019, p. 424-5, 615, 622.
  6. 张林芳. 百合固金汤加味治疗肺肾阴虚型非结核分枝杆菌肺病的临床观察. 成都中医药大学2019.
  7. Pilot quasi-randomized controlled study of herbal medicine Hochuekkito as an adjunct to conventional treatment for progressed pulmonary Mycobacterium avium complex disease. PLoS One 2014;9(8):e104411. https://doi.org/10.1371/journal.pone.0104411
  8. 전국한의과대학본초학교수. 본초학. 서울: 영림사; 2009, p. 216-8, 233-4, 240-1, 243-5, 270-1, 345-7, 389-91, 415-6, 485-6, 490-1, 496-8, 499-500, 519-20, 577-81, 589-91, 617-8, 630-4, 645-7, 683-4.
  9. Byun JS, Park YC, Yang SY, An, JJ, Park SA. Effects of Gamijinhae-tang and Socheongryongtang-ga-seokgo on PMA-induced Production of Airway Mucin and Expression of Airway MUC5AC Gene. Korean J Intern Med 2008;29(3):765-77.
  10. Sohn SH, Jang H, Kim Y, Jang YP, Cho SH, Jung H, et al. The effects of Gamijinhae-tang on elastase/lipopolysaccharide-induced lung inflammation in an animal model of acute lung injury. BMC Complement Altern Med 2013;13:176. https://doi.org/10.1186/1472-6882-13-176
  11. Kim DS, Um YR, Yang MC, Yun NY, Ma JY. Polyphenol contents and antioxidant activities of fractions from Ssanghwa-tang and fermented Ssanghwatang. Kor J Oriental Med 2010;16(3):175-8.
  12. KimIH, Hwang GJ. Studies on the Anti-inflammatory Activities of "Ssangwha-Tang". Korean J Pharmacogn 1981;12(3):131-5.
  13. Jung JC, Park DK. Studies on CNS - Depression and Antiinflammatory Action of Ssangwhatang. J Pharm Investig 1986;16(1):24-30.
  14. Chu CK, Kim JJ, Roh YL, Lee SH, Jeong SY, Jung HJ, et al. Experimental Research on the Effect of Haeyeol-tang. Kor J Oriental Med 2007;28(4):671-80.
  15. Seo MJ, Lee KB, Park JH, Hong SH. The Current Trend of Research about Bojungikki-tang. Korean J Orient Med 2010;16(2):83-90.
  16. Choi HM, Kim HH, Lee HD. Comparative Study of Bojungikgitang in Korea, Japan and China on the Anti-Inflammatory and Anti-Oxidative Effects. Kor J Herbology 2014;29(1):53-60. https://doi.org/10.6116/kjh.2014.29.1.53
  17. Cui J, Dong M, Yi L, Wei Y, Tang W, Zhu X, et al. Acupuncture inhibited airway inflammation and group 2 innate lymphoid cells in the lung in an ovalbumin-induced murine asthma model. Acupunct Med 2020;964528420924033.
  18. Luo W, Wang JY, Liu CL, Huang C. [Effect of electroacupuncture stimulation of "Feishu" (BL 13) on lung index, serum and lung IL-10 and TNF-alpha levels in mice with viral pneumonia]. Zhen Ci Yan Jiu 2014;39(4):293-7.
  19. Feng D, Zhou H, Jin X, Wei J, Zhang Q, Gu Y, et al. Electroacupuncture Pretreatment Alleviates LPS-Induced Acute Respiratory Distress Syndrome via Regulating the PPAR Gamma/NF-Kappa B Signaling Pathway. Evid Based Complement Alternat Med 2020;2020:4594631.
  20. Yeom MJ, Lee HC, Kim GH, Shim I, Lee HJ, Hahm DH. Therapeutic effects of Hominis placenta injection into an acupuncture point on the inflammatory responses in subchondral bone region of adjuvant-induced polyarthritic rat. Biol Pharm Bull 2003;26(10):1472-7. https://doi.org/10.1248/bpb.26.1472

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