The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)

The Society of Korean Medicine Obstetrics and Gynecology (대한한방부인과학회)
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Effect of Onkyung-tang on Cold Hypersensitivity on Feet: A Multi-center Double-blind Randomized Controlled Trial

온경탕이 족부냉증에 미치는 영향에 대한 다기관 이중맹검 무작위 대조군 연구

  • Kwon, Na-Yoen (Dept. of Korean Obstetrics and Gynecology, College of Korean Medicine, Se-Myung University) ;
  • Yoo, Joon-Sang (Dept. of Sasang Constitutional Medicine, College of Korean Medicine, Sang-Ji University) ;
  • Kim, Hyeong-Jun (Dept. of Korean Obstetrics and Gynecology, College of Korean Medicine, Se-Myung University) ;
  • Lee, Dong Nyung (Dept. of Korean Obstetrics and Gynecology, College of Korean Medicine, Se-Myung University)
  • 권나연 (세명대학교 한의과대학 한방부인과 교실) ;
  • 유준상 (상지대학교 한의과대학 사상체질의학교실) ;
  • 김형준 (세명대학교 한의과대학 한방부인과 교실) ;
  • 이동녕 (세명대학교 한의과대학 한방부인과 교실)
  • Received : 2020.07.18
  • Accepted : 2020.08.28
  • Published : 2020.08.28
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Abstract

Objectives: This study was aimed to figure out the effect of Onkyung-tang (OKT) on cold hypersensitivity on feet in female patients. Methods: This study was designed to implement multi-center randomized clinical trial in three korean medical hospitals. The female patients who were enrolled in this study were 112 women who suffered from cold hypersensitivity on feet. They were randomly allocated into OKT group or control group in 1:1 ratio. The primary outcome was change in score of visual analogue scale of hypersensitivity on feet, and the secondary outcomes were thermometer of LU4, PC8, ST32, LR3, visual analogue scale of hypersensitivity on hands, result of cold stress test, and score of World Health Organization Quality of Life-BREF. Results: In both group, the VAS of hypersensitivity on feet and hands was decreased while taking the medicine, and the effect of decreasing the VAS continues for the 4 weeks after the end of medication (p<0.001, 0.003, 0.001). In OKT group, the body temperature difference in lower extremity (ST32-LR3) was steadily decreased at every visit and it was statistically significant(p=0.003, <0.001). On the other hand, in control group, the body temperature difference in lower extremity was decreased only while taking the medicine (p<0.001). Conclusions: OKT significantly reduced discomfort coldness on feet in patients, and the effect of treatment was maintained at least for four weeks after medication.

Keywords

References

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