Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Steroid-resistant sarcoid myositis that was successfully treated with oral methotrexate

  • Noh, Kyung-Ha (Department of Neurology, Research Institute for Convergence of Biomedical Research, Pusan National University Yangsan Hospital) ;
  • Huh, So-Young (Department of Neurology, Kosin University College of Medicine) ;
  • Park, Young-Eun (Department of Neurology, Pusan National University Hospital) ;
  • Shin, Jin-Hong (Department of Neurology, Research Institute for Convergence of Biomedical Research, Pusan National University Yangsan Hospital) ;
  • Kim, Dae-Seong (Department of Neurology, Research Institute for Convergence of Biomedical Research, Pusan National University Yangsan Hospital)
  • Received : 2020.03.13
  • Accepted : 2020.03.17
  • Published : 2020.04.30
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Abstract

Acute sarcoid myositis is rarely complicated by sarcoidosis, and steroid therapy is considered the standard treatment. We experienced a patient with acute sarcoid myositis who did not respond to aggressive high-dose corticosteroid therapy, but showed a dramatic improvement after the addition of weekly low-dose oral methotrexate (MTX). This intervention allowed the resumption of normal daily activities after 6 months. Our case strongly suggests that MTX should be considered in patients with acute sarcoid myositis that is resistant to corticosteroid therapy.

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References

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