Journal of Korean Medicine for Obesity Research (한방비만학회지)

The Society of Korean Medicine for obesity Research (한방비만학회)
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A Comparative Study on the Quality of Sleep, Tongue Diagnosis, and Oral Microbiome in Accordance to the Korean Medicine Pattern Differentiation of Insomnia

불면 변증에 따른 수면의 질, 설진, 구강 미생물 차이에 대한 비교 연구

  • Shim, Hyeyoon (Department of Rehabilitation Medicine of Korean Medicine, College of Korean Medicine, Dongguk University) ;
  • Kwon, Ojin (Clinical Medicine Division, Korea Institute of Oriental Medicine) ;
  • Kim, Min-Jee (Department of Rehabilitation Medicine of Korean Medicine, College of Korean Medicine, Dongguk University) ;
  • Song, Eun-Ji (Research Group of Healthcare, Korea Food Research Institute) ;
  • Moon, Sun-Young (Clinical Medicine Division, Korea Institute of Oriental Medicine) ;
  • Nam, Young-Do (Research Group of Healthcare, Korea Food Research Institute) ;
  • Nam, Dong-Hyun (Department of Biofunctional Medicine and Diagnosis, College of Korean Medicine, Sangji University) ;
  • Lee, Jun-Hwan (Clinical Medicine Division, Korea Institute of Oriental Medicine) ;
  • Koo, Byung Soo (Department of Neuropsychiatry of Korean Medicine, College of Korean Medicine, Dongguk University) ;
  • Kim, Hojun (Department of Rehabilitation Medicine of Korean Medicine, College of Korean Medicine, Dongguk University)
  • 심혜윤 (동국대학교 한의과대학 한방재활의학교실) ;
  • 권오진 (한국한의학연구원 임상의학부) ;
  • 김민지 (동국대학교 한의과대학 한방재활의학교실) ;
  • 송은지 (한국식품연구원 헬스케어연구단) ;
  • 문선영 (한국한의학연구원 임상의학부) ;
  • 남영도 (한국식품연구원 헬스케어연구단) ;
  • 남동현 (상지대학교 한의과대학 진단생기능의학교실) ;
  • 이준환 (한국한의학연구원 임상의학부) ;
  • 구병수 (동국대학교 한의과대학 신경정신과학교실) ;
  • 김호준 (동국대학교 한의과대학 한방재활의학교실)
  • Received : 2020.05.17
  • Accepted : 2020.06.03
  • Published : 2020.06.30
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Abstract

Objectives: We aimed to compare the quality of sleep, tongue diagnosis, oral microbiology differences in insomnia of Liver qi stagnation (LQS) and Non-Liver qi stagnation (NLQS). Methods: 56 patients were classified as LQS or NLSQ type insomnia through the insomnia differentiation questionnaire. The depression scores between the groups were compared through beck depression inventory (BDI), and the sleep quality was compared through Pittsburgh sleep quality index (PSQI) and Insomnia Severity Index (ISI). We analyzed the sleep efficiency, total sleep time, total awake frequency, total and average awake time through actigraph. For the tongue diagnosis, the distribution of tongue coating in six areas were measured through Winkel tongue coating index (WTCI). Linear discriminant analysis was performed to observe the differences in composition of microbial strains between the groups. Results: The scores of BDI, ISI and PSQI were significantly higher in LQS group. The total sleep time in LQS group was significantly less than that of NLQS group. Among the areas of tongue, according to the WTCI, the amount of tongue coating in zones A and C was significantly small. In oral microbial analysis, there was no significant difference between the groups at the phylum level. At the genus level, Prevotella, Veillonella, and Streptococcus were predominant in LQS group, whereas Prevotella, Neisseria, and Streptococcus in NLQS group. Conclusions: It was meaningful that insomnia was more likely in LQS group than in NLQS group, and the composition of oral microorganisms was significantly different, which could lead to the diseases caused by stress.

Keywords

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