DOI QR코드

DOI QR Code

Endovascular Treatment of Cerebral Aneurysms: Technical Options in Coil Embolization

뇌동맥류의 혈관 내 치료: 코일색전술의 기술적 선택

  • Moon Hee Han (Department of Neurosurgery, VHS Medical Center)
  • 한문희 (중앙보훈병원 신경외과)
  • Received : 2019.12.21
  • Accepted : 2020.04.02
  • Published : 2020.05.01

Abstract

Since the endosaccular coil embolization technique was introduced as an alternative for treating selected patients with aneurysms, it has become a mainstay of treatment for cerebral aneurysms. In lesions with a neck larger than the aneurysmal body, an irregular shape, or arterial branches incorporated within the sac, endovascular treatment using detachable coils are traditionally contraindicated because of technical difficulties. Coil embolization has evolved as a result of both the development of related devices and the introduction of technical improvements using various devices. Use of various technical and device options can make endovascular treatment of cerebral aneurysms safer and can widen the treatment indications. Various technical options, including the technical modification of device-assisted techniques, will be presented, and the related practical points will be discussed in this issue.

뇌동맥류 치료에 있어 분리형 코일을 이용한 혈관 내 치료는 여러 기법의 발전으로 말미암아 그 임상적용 빈도가 수술적 치료의 빈도를 능가하여 뇌동맥류의 주된 치료 방법으로 자리 잡게 되었다. 혈관 내 치료의 임상적용이 확대된 데에는 기존 코일색전술이 가진 기술적 제한점을 극복할 수 있는 여러 치료기법들의 개발에 기인한 것인데, 특히 광경동맥류를 치료할 수 있는 여러 방법이 고안되었고, 그중에서 보조적인 기구를 함께 사용하는 여러 기법이 개발되어 사용되고 있다. 이 방법들은 치료의 과정에서 동맥류 내에 삽입되는 코일의 일부가 모동맥으로 빠져나오는 것을 방지하는 기법들이며, 기술적 난이도와 시술에 따른 위험도는 각 기법에 따라, 또한 병변과 주변 혈관의 양상에 따라 서로 달라서 상황에 따라 적절한 기법을 선택할 필요가 있으며, 원칙적으로 위험도가 가장 낮은 기법을 먼저 선택하여 시도하는 것인 바람직하다. 본 기고에서는 일반적인 뇌동맥류에서 혈관 내 치료의 기본적인 기법인 코일색전술에서, 기술적 제한점을 극복하는 여러 가지 보조적인 기법과 그 기술적 응용 및 주의점에 대하여 검토하고자 한다.

Keywords

References

  1. Guglielmi G, Vinuela F, Dion J, Duckwiler G. Electrothrombosis of saccular aneurysms via endovascular approach. Part 2: preliminary clinical experience. J Neurosurg 1991;75:8-14 
  2. Chang HW, Shin SH, Suh SH, Kim BS, Rho MH. Cost-effectiveness analysis of coiling versus neurosurgical clipping for intracranial aneurysms in Republic of Korea. Neurointervention 2016;11:86-91 
  3. Dmytriw AA, Phan K, Moore JM, Pereira VM, Krings T, Thomas AJ. On flow diversion: the changing landscape of intracerebral aneurysm management. AJNR Am J Neuroradiol 2019;40:591-600 
  4. Jia ZY, Shi HB, Miyachi S, Hwang SM, Sheen JJ, Song YS, et al. Development of new endovascular devices for aneurysm treatment. J Stroke 2018;20:46-56 
  5. Kwon OK, Kim SH, Kwon BJ, Kang HS, Kim JH, Oh CW, et al. Endovascular treatment of wide-necked aneurysms by using two microcatheters: techniques and outcomes in 25 patients. AJNR Am J Neuroradiol 2005;26:894-900 
  6. Cho YD, Rhim JK, Kang HS, Park JJ, Jeon JP, Kim JE, et al. Use of triple microcatheters for endovascular treatment of wide-necked intracranial aneurysms: a single center experience. Korean J Radiol 2015;16:1109-1118 
  7. Kwon OK, Kim SH, Oh CW, Han MH, Kang HS, Kwon BJ, et al. Embolization of wide-necked aneurysms with using three or more microcatheters. Acta Neurochir (Wien) 2006;148:1139-1145 
  8. Lee JY, Seo JH, Cho YD, Kang HS, Han MH. Endovascular treatment of wide-neck intracranial aneurysms using a microcatheter protective technique: results and outcomes in 75 aneurysms. AJNR Am J Neuroradiol 2011;32:917-922 
  9. Cho YD, Kang HS, Kim JE, Son YJ, Lee JY, Lee SJ, et al. Microcatheter looping technique for coil embolization of complex configuration middle cerebral artery aneurysms. Neurosurgery 2012;71:1185-1191 
  10. Cho YD, Kang HS, Kim JE, Ahn JH, Jung SC, Kim CH, et al. Microguidewire protection of wide-necked aneurysms incorporating orifices of tortuous acute-angled vessels: a novel approach. Neuroradiology 2014;56:553-559 
  11. Cho YD, Lee JY, Seo JH, Lee SJ, Kang HS, Kim JE, et al. Coil protection using small helical coils for wide-neck intracranial aneurysms: a novel approach. AJNR Am J Neuroradiol 2013;34:164-168 
  12. Cho YD, Rhim JK, Park JJ, Jeon JP, Kang HS, Kim JE, et al. Modified coil protection for proper coil frame configuration in wide-necked aneurysms. Neuroradiology 2015;57:705-711 
  13. Layton KF, Cloft HJ, Gray LA, Lewis DA, Kallmes DF. Balloon-assisted coiling of intracranial aneurysms: evaluation of local thrombus formation and symptomatic thromboembolic complications. AJNR Am J Neuroradiol 2007;28:1172-1175 
  14. Cho WS, Kang HS, Kim JE, Kwon OK, Oh CW, Cho YD, et al. Angle change of the parent arteries after stent-assisted coil embolization of wide-necked intracranial bifurcation aneurysms. Clin Radiol 2014;69:e63-70 
  15. Cho WS, Hong HS, Kang HS, Kim JE, Cho YD, Kwon OK, et al. Stability of cerebral aneurysms after stent-assisted coil embolization: a propensity score-matched analysis. Neurosurgery 2015;77:208-216; discussion 216-217 
  16. Jeon JP, Cho YD, Rhim JK, Park JJ, Cho WS, Kang HS, et al. Effect of stenting on progressive occlusion of small unruptured saccular intracranial aneurysms with residual sac immediately after coil embolization: a propensity score analysis. J Neurointerv Surg 2016;8:1025-1029 
  17. Choi HH, Lee JJ, Cho YD, Han MH, Cho WS, Kim JE, et al. Antiplatelet premedication for stent-assisted coil embolization of intracranial aneurysms: low dose prasugrel vs clopidogrel. Neurosurgery 2018;83:981-988 
  18. Cho YD, Lee WJ, Kim KM, Kang HS, Kim JE, Han MH. Stent-assisted coil embolization of posterior communicating artery aneurysms. AJNR Am J Neuroradiol 2013;34:2171-2176 
  19. Cho YD, Kang HS, Lee WJ, Kim KM, Kim JE, Han MH. Stent-assisted coil embolization of wide-necked posterior inferior cerebellar artery aneurysms. Neuroradiology 2013;55:877-882 
  20. Kwon HJ, Cho YD, Lim JW, Koh HS, Yoo DH, Kang HS, et al. Contralateral approach to coil embolization of proximal A1 aneurysms using the anterior communicating artery. AJNR Am J Neuroradiol 2018;39:2297-2300 
  21. Cho YD, Park SW, Lee JY, Seo JH, Kang HS, Kim JE, et al. Nonoverlapping Y-configuration stenting technique with dual closed-cell stents in wide-neck basilar tip aneurysms. Neurosurgery 2012;70:244-249 
  22. Cho YD, Kang HS, Kim JE, Cho WS, Kwon HJ, Koh HS, et al. Modified protection using far proximal portion of self-expandable closed-cell stents for embolization of wide-necked intracranial aneurysms. Neuroradiology 2014;56:851-857 
  23. Kwon BJ, Im SH, Park JC, Cho YD, Kang HS, Kim JE, et al. Shaping and navigating methods of microcatheters for endovascular treatment of paraclinoid aneurysms. Neurosurgery 2010;67:34-40 
  24. Kang HS, Han MH, Kwon BJ, Jung C, Kim JE, Kwon OK, et al. Is clopidogrel premedication useful to reduce thromboembolic events during coil embolization for unruptured intracranial aneurysms? Neurosurgery 2010;67:1371-1376 
  25. Ha EJ, Cho WS, Kim JE, Cho YD, Choi HH, Kim T, et al. Prophylactic antiplatelet medication in endovascular treatment of intracranial aneurysms: low-dose prasugrel versus clopidogrel. AJNR Am J Neuroradiol 2016;37:2060-2065 
  26. Cho WS, Lee J, Ha EJ, Kim KH, Lee J, Cho YD, et al. Low-dose prasugrel vs clopidogrel-based tailored premedication for endovascular treatment of cerebral aneurysms. Neurosurgery 2019;85:E52-E59 
  27. Kang HS, Kwon BJ, Roh HG, Yoon SW, Chang HW, Kim JE, et al. Intra-arterial tirofiban infusion for thromboembolism during endovascular treatment of intracranial aneurysms. Neurosurgery 2008;63:230-237; discussion 237-238 
  28. Cho YD, Lee JY, Seo JH, Kang HS, Kim JE, Jung KH, et al. Intra-arterial tirofiban infusion for thromboembolic complication during coil embolization of ruptured intracranial aneurysms. Eur J Radiol 2012;81:2833-2838