DOI QR코드

DOI QR Code

Convergence Analysis of Metabolic Syndrome Risk and Related Factors among Kidney Transplantation Recipients

신장이식 수혜자의 대사증후군 발생 위험 관련 요인에 대한 융복합적 조사연구

  • 정혜진 (국립순천대학교 간호학과)
  • Received : 2020.04.28
  • Accepted : 2020.05.20
  • Published : 2020.05.28

Abstract

The purpose of this study was to analyze the prevalence, and determine factors associated with metabolic syndrome risk among kidney transplantation recipients. This study data were collected by means of retrospective chart reviews for 111 kidney recipients at an organ transplantation center in South Korea. Data were analyzed using descriptive statistics, t-test or chi-squared test, and Pearson's correlation or Point biserial correlation. The prevalence of metabolic syndrome in our subjects was 65.8%. Metabolic syndrome was related with age, body mass index of before and after Kidney transplantation, and smoking. Study results indicate that intervention for modifying individual lifestyle behaviors is required to prevent and reduce their prevalence of metabolic syndrome after kidney transplantation.

본 연구는 신장이식 수혜자들의 대사증후군 유병율을 조사하고 발생 위험 관련요인을 확인하기 위해 시행되었다. 본 연구는 의무기록을 이용한 후향적 조사연구로 국내 장기이식센터 신장이식 클리닉에 내원한 신장이식 수혜자 총 111명을 대상으로 관련 자료를 수집하였다. 자료 분석에는 t-test, χ2-test 및 Pearson's correlation, Point biserial correlation을 시행하였다. 연구 결과 신장이식 수혜자들의 대사증후군 유병 현황은 65.8%로 나타났으며 대사증후군 발생위험과 관련된 요인으로 나이, 이식 전 체질량지수, 이식 후 체질량지수, 흡연으로 확인되었다. 본 연구 결과는 신장이식 수혜자들의 대사증후군 진단 항목에 대해 지속적으로 모니터링하고 조절 가능한 생활습관 관련 요인들의 적극적 중재를 통해 조기 예방 및 관리가 필요함을 시사한다.

Keywords

References

  1. S. Fishbane & V. Nair. (2018). Opportunities for increasing the rate of preemptive kidney transplantation. Clinical Journal of the American Society of Nephrology, 13(8), 1280-1282. DOI : 10.2215/CJN.02480218
  2. Korea Network for Organ Sharing (2019). Annual report. https://www.konos.go.kr/konosis/sub4/sub04_06_01.jsp?menuId=x&menuImg=subImg06&submenuImg=x
  3. B. S. Cha & J. H. Moon. (2011). Management of Posttransplantation Diabetes Mellitus (PTDM). Journal Korean Soc Transplant, 25, 8-14. DOI: 10.4285/jkstn.2011.25.1.8
  4. H. S. Park. et al. (2003). Prevalence and Associated Factors with Metabolic Syndrome in South Korea-From the Korean National Health and Nutrition Examination Survey. Korean Journal of Obesity, 12(1), 1-14.
  5. D. E. Hricik. (2011). Metabolic syndrome in kidney transplantation: management of risk factors. Clinical Journal of the American Society of Nephrology, 6(7), 1781-1785. DOI: 10.2215/CJN.01200211
  6. E. Porrini. et al. (2006). Impact of metabolic syndrome on graft function and survival after cadaveric renal transplantation. American journal of kidney diseases, 48(1), 134-142. DOI: 10.1053/j.ajkd.2006.04.078
  7. K. K. Koh, S. H. Han, & M. J. Quon. (2005). Inflammatory markers and the metabolic syndrome: insights from therapeutic interventions. Journal of the American College of Cardiology, 46(11), 1978-1985. DOI: 10.1016/j.jacc.2005.06.082
  8. K. S. Han, Y. H. Park, S. N. Kim, S. J. Lee, & S. H. Yang. (2013). Influencing factors on quality of life in patients with metabolic syndrome. The Korean Journal of Stress Research, 21(4), 303-311. DOI: 10.4040/jkan. 20 15.45.3.420
  9. P. S. Jellinger, Y. Handelsman, P. D. Rosenblit, Z. T. Bloomgarden, V. A. Fonseca, & A. J. Garber. (2017). American association of clinical endocrinologists and American college of endocrinology guidelines for management of dyslipidemia and prevention of cardiovascular disease. Endocrine Practice, 23(2), 1-87. DOI: 10.4158/EP171764.APPGL
  10. K. S. Han, Y. H. Park, S. N. Kim, S. J. Lee, & S. H. Yang, Influencing factors on quality of life in patients with metabolic syndrome. (2013). The Korean Journal of Stress Research, 21(4), 303-311. DOI: 10.4069/kjwhn.2013.19.1.1
  11. M. Y. Im, Y. R. Lee, S. J. Han, & C. M. Cho. (2012). The effects of lifestyle factors on metabolic syndrome among Korean adults. Journal of Korean Academy of Community Health Nursing, 23(1), 13-21. DOI: 10.12799/ jkachn.2012.23.1.13
  12. National, Cholesterol Education Program NCEP. (2002). Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report. Circulation, 106(25), 3143. https://doi.org/10.1161/circ.106.25.3143
  13. S. Lee. et al. (2006). Cut-off points of waist circumference for defining abdominal obesity in the Korean population. The Korean Journal of Obesity, 15(1), 1-9.
  14. J. Y. Kim. (2019. 3. 28). Increased prevaalence of Korean metabolic syndrome with age. http://m.mostonline.co.kr/ news/articleView.html?idxno=96183
  15. A. P. De Vries. et al. (2004). Metabolic syndrome is associated with impaired long‐term renal allograft function; not all component criteria contribute equally. American Journal of Transplantation, 4(10), 1675-1683. DOI: 10.1111/j.1600-6143.2004.00558.x
  16. G. Fernández-Fresnedo, E. Rodrigo, R. Valero, & M. Arias. (2006). Traditional cardiovascular risk factors as clinical markers after kidney transplantation. Transplantation Reviews, 20(2), 88-94. DOI: 10.1016/j.trre.2006.05.004
  17. M. K. Kim & J. H. Park. (2012). Metabolic Syndrom. Journal of the Korean Medical Association, 55(10), 1005-1013. DOI: 10.5124/ jkma.2012.55.10.1005
  18. H. S. Kim & S. H. Jeong. (2006). Differences in Prevalence and Risk Factors of the Metabolic Syndrome by Gender in Type 2 Diabetic Patients. Korean Society of Adult Nursing. 18(1), 3-9.
  19. H. M. Kang & D. J. Kim. (2012). Gender differences in the association of socioeconomic status with metabolic syndrome in middle-aged Koreans. The Korean Journal of Medicine, 82(5), 569-575. DOI: 10.3904/kjm.2012.82.5.569
  20. E. Kim & S. W. Oh. (2012). Gender differences in the association of occupation with metabolic syndrome in Korean adults. The Korean Journal of Obesity, 21(2), 108-114. DOI: 10.7570/kjo.2012. 21.2.108
  21. E. S. Ford, W. H. Giles, & W. H. Dietz. (2002). Prevalence of the metabolic syndrome among US adults: Findings from the third national health and nutrition examination survey. Journal of the American Medical Association, 287(3), 356-359. DOI: 10.1001/jama.287.3.356
  22. A. C. Webster, R. C. Woodroffe, R. S. Taylor, J. R. Chapman, & J. C. Craig. (2005) Tacrolimus versus ciclosporin as primary immunosuppression for kidney transplant recipients: meta-analysis and meta-regression of randomised trial data. British Medical Journal, 331(7520), 810. DOI: 10.1136/bmj.38569.471007.AE
  23. J. H. Macdonald, D. Kirkman, & M. Bani. (2009). Kidney transplantation: a systematic review of interventional and observational studies of physical activity on intermediate outcomes. Advances in chronic kidney disease, 16(6), 482-500. DOI: 10.1053/j.ackd.2009.07.011
  24. E. F. Pedrollo. et al. (2016). Effects of metabolic syndrome on kidney transplantation outcomes: a systematic review and meta‐analysis. Transplant International, 29(10), 1059-1066. DOI: 10.1111/tri.12805
  25. W. H. Cho. et al. (2017). Rehabilitation of Transplant and Transplant Games. The Journal of the Korean Society for Transplantation, 31(1), 6-15. DOI: 10.4285/jkstn.2017.31.1.6
  26. C. H. Jung, J. S. Park, W. Y. Lee, & S. W. Kim. (2002). Effects of smoking, alcohol, exercise, level of education, and family history on the metabolic syndrome in Korean adults, The Korean Journal Med. 63(6), 649-660.
  27. W. A. Calo, A. P. Ortiz, E. Suarez, M. Guzman , & C. M. Perez. (2013). Association of cigarette smoking and metabolic syndrome in a Puerto Rican adult population. Int J Prev Med, 15(4), 810-816. DOI: 10.1007/s10903-012-9660-0
  28. A. R. Hong, K. S. Lee, S. Y. Lee, & J. H. Yu. (2009). Association of current and past smoking with metabolic syndrome in men. Journal of Preventive Medicine and Public Health, 42(3), 160-164. DOI: 10.3961/jpmph.2009.42.3.160