Journal of Dental Anesthesia and Pain Medicine

  • 제20권1호
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  • Pages.1-8
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  • 2020
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  • 2383-9309(pISSN)
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  • 2383-9317(eISSN)
대한치과마취과학회 (The Korean Dental Society of Anesthsiology)
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Midazolam use in pediatric dentistry: a review

  • Jain, Shreyans Aditya (Department of Paedodontics and Preventive Dentistry, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences) ;
  • Rathi, Nilesh (Department of Paedodontics and Preventive Dentistry, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences) ;
  • Thosar, Nilima (Department of Paedodontics and Preventive Dentistry, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences) ;
  • Baliga, Sudhindra (Department of Paedodontics and Preventive Dentistry, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences)
  • 투고 : 2019.01.15
  • 심사 : 2020.02.08
  • 발행 : 2020.02.28
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초록

Behaviour management and dental procedures performed in very young, pre-cooperative, highly anxious, or medically disabled children are challenging tasks. Various drugs and methods have, however, been introduced to facilitate treatment for this patient population. Midazolam is a benzodiazepine used as an adjunct to behavior management techniques in the dental treatment of pediatric patients. Midazolam can be used as a safe and effective drug for conscious sedation, general anesthetic premedication, and treatment of seizures during dental procedures. Nevertheless, further research involving pediatric patients would be beneficial.

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참고문헌

  1. Torres-Perez J, Tapia-Garcia I, Rosales-Berber MA, Hernandez-Sierra JF, Pozos-Guillen Ade J. Comparison of three conscious sedation regimens for pediatric dental patients. J Clin Pediatr Dent 2007; 31: 183-6. https://doi.org/10.17796/jcpd.31.3.e82526q0432375n0
  2. Nordt SP, Clark RF. Midazolam: a review of therapeutic uses and toxicity. J Emerg Med 1997; 15: 357-65. https://doi.org/10.1016/S0736-4679(97)00022-X
  3. Craig D, Skelly M. Practical conscious sedation. London: Quintessence publishing; 2004.
  4. Folayan MO, Faponle A, Lamikanra A. Seminars on controversial issues. A review of the pharmacological approach to the management of dental anxiety in children. Int J Paediatr Dent 2002; 12: 347-54. https://doi.org/10.1046/j.1365-263X.2002.03812.x
  5. Payne K, Mattheyse FJ, Liebenberg D, Dawes T. The pharmacokinetics of midazolam in paediatric patients. Eur J Clin Pharmacol 1989; 37: 267-72. https://doi.org/10.1007/BF00679782
  6. McMillan CO, Spahr-Schopfer IA, Sikich N, Hartley E, Lerman J. Premedication of children with oral midazolam. Can J Anaesth 1992; 39: 545-50. https://doi.org/10.1007/BF03008315
  7. Weldon BC, Watcha MF, White PF. Oral midazolam in children: effect of time and adjunctive therapy. Anesth Analg 1992; 75: 51-5.
  8. Merritt P, Hirshman E, Hsu J, Berrigan M. Metamemory without the memory: are people aware of midazolaminduced amnesia? Psychopharmacol 2005; 177: 336-43. https://doi.org/10.1007/s00213-004-1958-8
  9. Hosey MT, Fayle S. Pharmaceutical prescribing for children. Part 5. Conscious sedation for dentistry in children. Prim Dent Care 2006; 13: 93-6. https://doi.org/10.1308/135576106777795554
  10. Massanari M, Novitsky J, Reinstein LJ. Paradoxical reactions in children associated with midazolam use during endoscopy. Clin Pediatr (Phila) 1997; 36: 681-4. https://doi.org/10.1177/000992289703601202
  11. British National Formulary. 2014. Available from: http://www.bnf.org.
  12. Hallonsten AL, Jensen B, Raadal M, Veerkamp J, Hosey MT, Poulsen S. European Academy of Paediatric Dentistry guidelines on conscious sedation in paediatric dentistry. 2003.
  13. UK national clinical guidelines in paediatric dentistry. managing anxious children: the use of conscious sedation in paediatric dentistry. Int J Paediatr Dent 2002; 12: 359-72.
  14. National Clinical Guideline Centre. Sedation in children and young people: sedation for diagnostic and therapeutic procedures in children and young people. London: Royal College of Physicians (UK); 2010.
  15. Standing dental advisory committee. Conscious sedation in the provision of dental care: report of an expert group for sedation in dentistry. London: UK Department Of Health; 2003.
  16. Matharu L, Ashley PF. Sedation of anxious children undergoing dental treatment. Cochrane Database Syst Rev 2006; 25: CD003877.
  17. Fukuta O, Braham RL, Yanase H, Atsumi N, Kurosu K. The sedative effect of intranasal midazolam administration in the dental treatment of patients with mental disabilities. Part 1. The effect of a 0.2 mg/kg dose. J Clin Pediatr Dent 1993; 17: 231-7.
  18. Fukuta O, Braham RL, Yanase H, Kurosu K. The sedative effects of intranasal midazolam administration in the dental treatment of patients with mental disabilities. Part 2: optimal concentration of intranasal midazolam. J Clin Pediatr Dent 1994; 18: 259-65.
  19. Fukuta O, Braham RL, Yanase H, Kurosu K. Intranasal administration of midazolam: pharmacokinetic and pharmacodynamics properties and sedative potential. ASDC J Dent Child 1997; 64: 89-98.
  20. Isik B, Baygin O, Bodur H. Effect of drinks that are added as flavoring in oral midazolam premedication on sedation success. Paediatr Anaesth 2008; 18: 494-500. https://doi.org/10.1111/j.1460-9592.2008.02462.x
  21. Lourenco-Matharu L, Roberts GJ. Oral sedation for dental treatment in young children in a hospital setting. Br Dent J 2010; 209: E12. https://doi.org/10.1038/sj.bdj.2010.886
  22. Wilson KE, Welbury RR, Girdler NM. A study of the effectiveness of oral midazolam sedation for orthodontic extraction of permanent teeth in children: a prospective, randomised, controlled, crossover trial. Br Dent J 2002; 192: 457-62. https://doi.org/10.1038/sj.bdj.4801400
  23. Wilson KE, Girdler NM, Welbury RR. A comparison of oral midazolam and nitrous oxide sedation for dental extractions in children. Anaesthesia 2006; 61: 1138-44. https://doi.org/10.1111/j.1365-2044.2006.04835.x
  24. Fuks AB, Kaufman E, Ram D, Hovav S, Shapira J. Assessment of two doses of intranasal midazolam for sedation of young pediatric dental patients. Pediatr Dent 1994; 16: 301-5.
  25. Mazaheri R, Eshghi A, Bashardoost N, Kavyani N. Assessment of intranasal midazolam administration with a dose of 0.5 mg/kg in behavior management of uncooperative children. J Clin Pediatr Dent 2008; 32: 95-9.
  26. Hartgraves PM, Primosch RE. An evaluation of oral and nasal midazolam for pediatric dental sedation. ASDC J Dent Child 1994; 61: 175-81.
  27. Karl HW, Rosenberger JL, Larach MG, Ruffle JM. Transmucosal administration of midazolam for premedication of pediatric patients. Comparison of the nasal and sublingual routes. Anesthesiology 1993; 78: 885-91. https://doi.org/10.1097/00000542-199305000-00013
  28. Robb ND, Hosey MT, Leitch JA. Intravenous conscious sedation in patients under 16 years of age. Fact or fiction? Br Dent J 2003; 194: 469-71. https://doi.org/10.1038/sj.bdj.4810172
  29. Saint-Maurice C, Meistelman C, Rey E, Esteve C, de Lauture D, Olive G. The pharmacokinetics of rectal midazolam for premedication in children. Anesthesiology 1986; 65: 536-8. https://doi.org/10.1097/00000542-198611000-00019
  30. Roelofse JA, Stegmann DH, Hartshorne J, Joubert JJ. Paradoxical reactions to rectal midazolam as premedication in children. Int J Oral Maxillofac Surg 1990; 19: 2-6. https://doi.org/10.1016/S0901-5027(05)80558-2
  31. Alderson PJ, Lerman J. Oral premedication for paediatric ambulatory anaesthesia: a comparison of midazolam and ketamine. Can J Anaesth 1994; 41: 221-6. https://doi.org/10.1007/BF03009834
  32. Feld LH, Negus JB, White PF. Oral midazolam preanesthetic medication in pediatric outpatients. Anesthesiology 1990; 73: 831-4. https://doi.org/10.1097/00000542-199011000-00006
  33. Parnis SJ, Foate JA, van der Walt JH, Short T, Crowe CE. Oral midazolam is an effective premedication for children having daystay anaesthesia. Anaesth Intensive Care 1992; 20: 9-14. https://doi.org/10.1177/0310057X9202000102
  34. Wilton NC, Leigh J, Rosen DR, Pandit UA. Preanesthetic sedation of preschool children using intranasal midazolam. Anesthesiology 1988; 69: 972-5. https://doi.org/10.1097/00000542-198812000-00032
  35. Weber F, Wulf H, el Saeidi G. Premedication with nasal s-ketamine and midazolam provides good conditions for induction of anesthesia in preschool children. Can J Anaesth 2003; 50: 470-5. https://doi.org/10.1007/BF03021058
  36. Millar K, Asbury AJ, Bowman AW, Hosey MT, Martin K, Musiello T, et al. A randomised placebo-controlled trial of the effects of midazolam premedication on children's postoperative cognition. Anaesthesia 2007; 62: 923-30. https://doi.org/10.1111/j.1365-2044.2007.05148.x
  37. Hosey MT, Asbury AJ, Bowman AW, Millar K, Martin K, Musiello T, et al. The effect of transmucosal 0.2 mg/kg midazolam premedication on dental anxiety, anaesthetic induction and psychological morbidity in children undergoing general anaesthesia for tooth extraction. Br Dent J 2009; 207: E2. https://doi.org/10.1038/sj.bdj.2009.570
  38. Kain ZN, Mayes LC, Wang SM, Hofstadter MB. Postoperative behavioral outcomes in children: effects of sedative premedication. Anesthesiology 1999; 90: 758-65. https://doi.org/10.1097/00000542-199903000-00018
  39. Finley GA, Stewart SH, Buffett-Jerrott S, Wright KD, Millington D. High levels of impulsivity may contraindicate midazolam premedication in children. Can J Anaesth 2006; 53: 73-8. https://doi.org/10.1007/BF03021530
  40. Viitanen H, Annila P, Viitanen M, Yli-Hankala A. Midazolam premedication delays recovery from propofolinduced sevoflurane anesthesia in children 1-3 yr. Can J Anaesth 1999; 46: 766-71. https://doi.org/10.1007/BF03013912
  41. Cox RG, Nemish U, Ewen A, Crowe MJ. Evidence-based clinical update: does premedication with oral midazolam lead to improved behavioural outcomes in children? Can J Anaesth 2006; 53: 1213-9. https://doi.org/10.1007/BF03021583
  42. Ashrafi MR, Khosroshahi N, Karimi P, Malamiri RA, Bavarian B, Zarch AV, et al. Efficacy and usability of buccal midazolam in controlling acute prolonged convulsive seizures in children. Eur J Paediatr Neurol 2010; 14: 434-8. https://doi.org/10.1016/j.ejpn.2010.05.009
  43. Holsti M, Dudley N, Schunk J, Adelgais K, Greenberg R, Olsen C, et al. Intranasal midazolam vs rectal diazepam for the home treatment of acute seizures in pediatric patients with epilepsy. Arch Pediatr Adolesc Med 2010; 164: 747-53. https://doi.org/10.1001/archpediatrics.2010.130
  44. Appleton R, Macleod S, Martland T. Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children. Cochrane Database Syst Rev 2008: Cd001905.
  45. Papineni A, Lourenco-Matharu L, Ashley PF. Safety of oral midazolam sedation use in paediatric dentistry: a review. Int J Paediatr Dent 2014; 24: 2-13.