Archives of Craniofacial Surgery (대한두개안면성형외과학회지)

Korean Cleft Palate-Craniofacial Association (대한두개안면성형외과학회)
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Primary amelanotic melanoma of the mandibular gingiva

  • Kim, Byeong Jun (Pop Plastic Surgery Clinic) ;
  • Kim, Hyeong Seop (Department of Plastic and Reconstructive Surgery, Kangdong Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Chang, Yong Joon (Department of Plastic and Reconstructive Surgery, Kangdong Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Kwon, Kee Hwan (Department of Otolaryngology-Head and Neck Surgery, Kangdong Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Cho, Seong Jin (Department of Pathology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine)
  • Received : 2019.10.25
  • Accepted : 2020.04.02
  • Published : 2020.04.20
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Abstract

Oral mucosal melanoma is a very rare type of malignant melanoma, the characteristics of which differ from those of cutaneous melanoma. Primary amelanotic melanoma of the mandibular gingiva, which can invade the mandibular bone, is very rare worldwide. Here, we report a case in which we performed a reconstruction of the mandible and gingiva using the fibula osteocutaneous free flap procedure to treat a patient diagnosed with a primary amelanotic melanoma of the mandibular gingiva. The procedure was successful, and no recurrence was observed 10 months after surgery. Oral mucosal melanoma has a much poorer prognosis and a lower 5-year survival rate than cutaneous melanoma. However, recently, immunomodulatory therapies for mutations in melanocytic lesions have been used effectively to treat the increasing number of patients developing this type of melanoma, thus improving the prognosis of patients with oral mucosal melanoma.

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References

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