Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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Efficacy and Safety of Miniscalpel Acupuncture, Non-Steroidal Anti-Inflammatory Drugs or Combined Treatment for Chronic Neck Pain: An Assessor-Blinded Randomized Controlled Pilot Study

만성 경항통(목부위 통증)의 도침요법, 진통제, 복합치료의 효능 및 안전성 연구

  • Gong, Han Mi (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Jun, Seungah (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Chung, Yeon-Joong (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Kim, Ju-Ran (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Lee, Jung Hee (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Lee, Hyun-Jong (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Park, Chung A (Department of Diagnostics, College of Korean Medicine, Daegu Haany University) ;
  • Kim, Jae Soo (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University)
  • 공한미 (대구한의대학교 한의과대학 침구의학교실) ;
  • 전승아 (대구한의대학교 한의과대학 침구의학교실) ;
  • 정연중 (대구한의대학교 한의과대학 침구의학교실) ;
  • 김주란 (대구한의대학교 한의과대학 침구의학교실) ;
  • 이정희 (대구한의대학교 한의과대학 침구의학교실) ;
  • 이현종 (대구한의대학교 한의과대학 침구의학교실) ;
  • 박정아 (대구한의대학교 한의과대학 진단학교실) ;
  • 김재수 (대구한의대학교 한의과대학 침구의학교실)
  • Received : 2020.02.20
  • Accepted : 2020.03.09
  • Published : 2020.03.27
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Abstract

Objectives : We investigated the efficacy and safety of miniscalpel acupuncture (MA) treatment combined with non-steroidal anti-inflammatory drugs (NSAIDs) for chronic neck pain (CNP) in an assessor-blinded randomized controlled pilot trial to establish a basis for larger-scale randomized controlled studies on this subject. Methods : Participants (n=36) were recruited and randomly allocated to the MA group, NSAIDs and combined treatment group. The MA group received MA three times over three weeks. The NSAIDs group was administered orally with zaltoprofen 80mg t.i.d. over three weeks. The combined treatment group received MA and zaltoprofen in the same manner as MA and NSAIDs groups. The primary outcome was pain as assessed by a visual analogue scale (VAS) and the secondary outcomes were assessed using the Neck Disability index (NDI), EuroQol 5-dimension questionnaire (EQ-5D), and Patients' Global Impression of Change scale (PGIC). Assessments were made at week 0 (baseline), 1, 2, 3 (primary end point) during treatment and at week 7 (4 weeks after the end of treatment). Results : 35 participants completed the study. No serious adverse event occurred and blood test results were within normal limits. The improvement of VAS and NDI was significantly greater in combined and MA group than that in NSAIDs group (p<0.017). The combined group showed better outcomes in EQ-5D at visit 2 and 5, in PGIC at visit 4 than the NSAIDs group (p<0.017). No significant differences were found between combined and MA group. Conclusions : Our results suggest that both combined and MA group can be more effective in improving pain control than NSAIDs group. A large-scale clinical study is warranted to further clarify these findings.

Keywords

References

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