Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Adverse Event Report in Cattle Following Foot-and-Mouth Disease Vaccination in Daejeon Province

대전지역 소에서 구제역 백신 접종후의 부작용에 대한 조사

  • Jeong, Sangil (College of Veterinary Medicine & Research Institute of Veterinary Medicine, Chungnam National University) ;
  • cho, Daehee (College of Veterinary Medicine & Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Cho, Nayoung (College of Veterinary Medicine & Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Park, Seongjun (College of Veterinary Medicine & Research Institute of Veterinary Medicine, Chungnam National University)
  • Received : 2019.12.11
  • Accepted : 2020.12.18
  • Published : 2020.12.31
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Abstract

Few studies of the side effects of the FMD vaccine have been performed domestically and studies in accordance to region have been limited. This study was performed by inoculating cows raised in the Daejeon province with the FMD vaccine and observing the side effects following inoculation. From January to February of 2011, 3,378 cows vaccinated with the FMD vaccine, in 143 different farms in the Daejeon province were analysed for adverse effects after inoculation. A total of 66 cows showed adverse effects after the first FMD vaccination and adverse effects observed were abortion/stillbirth (24, 36.4%), death (19, 28.8%), premature birth (14, 21.2%), skin lesions (8, 12.1%), vaginal swelling (1, 1.5%). A total of 29 cows showed adverse effects after the second FMD vaccination and adverse effects observed were abortion/stillbirth (17, 58.6%), premature birth (5, 17.2%), facial swelling (4, 13.8%), death (3, 10.3%). Through these results, continuous national research of the side effects of the FMD vaccine should be carried out continuously henceforth.

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References

  1. 김동민, 백신접종뒤 폐사·유산 244건, 충청일보, 2011.2.27.
  2. 박최규. 구제역 백신의 특성과 올바른 사용방법. 대한수의사회지. 2012; 48: 144-149.
  3. 배상현, 전남 구제역 백신접종 후 소 134마리 폐사, 뉴시스, 2011.1.23.
  4. 양승복, 구제역 백신접종 후 사고 301마리, 경북일보, 2011.1.18.
  5. 윤성효, 경남, 구제역 백신접종 뒤에도 폐사 등 320건 피해발생, 2011.2.6.
  6. Barnett PV, Cox SJ, Aggarwal N, Gerber H, McCullough KC. Further studies on the early protective responses of pigs following immunization with high potency foot and mouth disease vaccine. Vaccine 2002; 20: 3197-3208. https://doi.org/10.1016/S0264-410X(02)00242-6
  7. Divers TJ, Peek SF. Skin disease. In: Rebhun's Diseases of dairy cattle. 2nd ed. St. Louis: Saunders. 2008: 305-308.
  8. FAD PReP/NAHEMS Guidelines: Vaccination for Foot-and-Mouth Disease. 2011.
  9. Gyeonggi-do, Foot-and-Mouth Disease white paper, 2011.
  10. Kitching RP. Flinical vacriation in foot and mouth disease: cattle. Rev sci tech Off Int Epiz 2002; 21: 499-504. https://doi.org/10.20506/rst.21.3.1343
  11. King AMQ, Brown F, Christian P, Hovi T, Hyypia T, Knowles NJ, Lemon SM, Minor PD, Palmenberg AC, Skern T, Stanway G. Picornaviridae. In: Virus taxonomy: classification and nomenclature of viruses. Seventh report of the international committee on taxonomy of viruses. San Diego. Academic Press. 2000: 657-673.
  12. Mahy WJ, van Regenmortel HV. Foot and Mouth Disease Viruses. In: Desk encyclopedia of Animal and Bacterial Virology. Oxford: Elsevier. 2010: 131-139.
  13. Murphy FA, Gibbs JEP, Horzinek MC, Studdert MJ. Veterinary and Zoonotic Viral Disease. In: Veterinary Virology 3rd ed. California: Elsevier. 1999: 521-528.
  14. Omidi A. Anaphylactic reaction in a cow due to parenteral administration of penicillin-streptomycin. Can Vet J 2009; 50: 741-744.
  15. Park JH, Park JY, Kim YJ, Oem JK, Lee KN, Kye SJ, Joo YS. Vaccination as a control measure during the outbreak of foot-and-mouth disease in 2000 in Korea. Dev Biol (Basel) 2004; 119: 63-70.
  16. Pluimer FH. Foot-and-Mouth disease control using vaccination: the Dutch experience in 2001. Dev Boil (Basel) 2004; 119: 41-49.
  17. Saraiva V, Darsie G. The use of vaccines in south American foot-and-mouth disease eradication programmes. Dev Biol (Basel) 2004; 119: 33-40.
  18. Sorensen JH, Kackay DK, Jensen CO, Donaldson AI. An integrated model to predict the atmospheric spread of foot-and-mouth disease virus. Epidemiol Infect 2000; 124: 577-590. https://doi.org/10.1017/S095026889900401X