Parasites, Hosts and Diseases

  • 제58권5호
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  • Pages.577-581
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  • 2020
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  • 2982-5164(pISSN)
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  • 1738-0006(eISSN)
대한기생충학·열대의학회 (The Korea Society for Parasitology and Tropical Medicine)
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Ocular Sparganosis: The First Report of Spirometra ranarum in Thailand

  • Saksirisampant, Wilai (Department of Parasitology, Faculty of Medicine, Chulalongkorn University) ;
  • Eamudomkarn, Chatanun (Department of Parasitology, Parasite Research Center and Parasite Resource Bank, Chungbuk National University School of Medicine) ;
  • Jeon, Hyeong-Kyu (Department of Parasitology, Parasite Research Center and Parasite Resource Bank, Chungbuk National University School of Medicine) ;
  • Eom, Keeseon S. (Department of Parasitology, Parasite Research Center and Parasite Resource Bank, Chungbuk National University School of Medicine) ;
  • Assavapongpaiboon, Buravej (Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University) ;
  • Sintuwong, Sunisa (Mettapracharak Eye Centre, Mettapracharak (Wat Raikhing) Hospital) ;
  • Tulvatana, Wasee (Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University)
  • 투고 : 2020.04.03
  • 심사 : 2020.08.22
  • 발행 : 2020.10.31
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초록

A 22-year-old Thai man from the Northeast region presented with acute eye swelling, itching, and discharge on his left eye. He was suspected of having gnathostomiasis and treated with albendazole and prednisolone for 3 weeks. Nine months later, he was treated with high-dose oral prednisolone for the preliminary and differential diagnoses with thyroid-associated orbitopathy and lymphoma. He had been administered prednisolone intermittently over a few years. Then he developed a painless movable mass at the left upper eyelid and recurrent pseudotumor oculi was suspected. The surgical removal of the mass was performed. A white pseudosegmented worm revealed a definite diagnosis of ocular sparganosis by a plerocercoid larva. Molecular diagnosis of the causative species was made based on the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene. Proper technique of extraction and amplification of short fragments DNA from formalin-fixed paraffin-embedded tissue successfully identified parasite species. The result from the sequencing of the PCR-amplified cox1 fragments in this study showed 99.0% sequence homology to Spirometra ranarum. This is the first report of S. ranarum in Thailand.

키워드

참고문헌

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피인용 문헌

  1. An annotated checklist of the eukaryotic parasites of humans, exclusive of fungi and algae vol.1069, 2020, https://doi.org/10.3897/zookeys.1069.67403