Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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Non-Invasive HbA1c Measurement Using Two-Wavelength Raman Scattering

2 파장 라만 산란을 이용한 비침습적 HbA1c 측정

  • Yang, Jooran (Department of Electrical Engineering, Kyungpook National University) ;
  • Kim, Hyungpyo (Department of Electrical Engineering, Kyungpook National University)
  • 양주란 (경북대학교 전기공학과) ;
  • 김형표 (경북대학교 전기공학과)
  • Received : 2019.08.16
  • Accepted : 2019.09.27
  • Published : 2019.09.30
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Abstract

The purpose of this study is to classify the concentration of HbA1c (glycosylated hemoglobin), which is an indicator in the management of accurate blood glucose level in diabetic patients, using a non-invasive optical property measurement method. To measure the optical properties of HbA1c, the optical source uses LEDs and laser diodes of 400 nm in the visible region and 1450 nm in the nearinfrared region using thermopile to detect the Raman scattering intensity. An HbA1c control solution was used. As a result, the optical properties of 5% (normal) and 9% (abnormal) HbA1c control solutions showed specificity in which the output values were reversed at 850 nm and 950 nm, respectively. This property was applied to distinguish between normal and abnormal values in diabetes. In addition, considering tissue penetration depths for non-invasive measurements, two wavelengths were determined to be effective in distinguishing the concentrations of HbA1c control solutions at 5%, 7%, and 9%.

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