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Impact of Depression on Medication Adherence of Patients with Systemic Lupus Erythematosus: Focusing on Mediating Effect of Self-Efficacy and Belief about Medication

전신성 홍반성 루푸스 환자의 우울이 복약순응도에 미치는 영향: 자기효능감과 약물에 대한 신념의 매개 효과를 중심으로

  • Lee, Su Jin (Department of Nursing, Dong-A University Hospital.Department of Nursing, Dong-A University) ;
  • Ju, Hyeon Ok (Department of Nursing, Dong-A University)
  • 이수진 (동아대학교병원 간호사.동아대학교 간호학과) ;
  • 주현옥 (동아대학교 간호학과)
  • Received : 2019.05.30
  • Accepted : 2019.06.24
  • Published : 2019.08.31

Abstract

Purpose: The purpose of this study was to determine the mediating effects of self-efficacy and the belief about medication on the association between depression and medication adherence in patients with systemic lupus erythematosus. Methods: 128 patients aged ${\geq}19years$, who were regular outpatients or admitted patients diagnosed with systemic lupus erythematosus at a tertiary hospital in B city, participated in this study. Data were collected by using a self-administered questionnaire. Testing of mediating effects was analyzed by a parallel redundant mediated model using the PROCESS macro for SPSS version 3.3. Results: They scored an average of $16.71{\pm}11.13$ for depression, $694.14{\pm}170.68$ for self-efficacy, $3.05{\pm}4.60$ for the belief about medication, and $90.14{\pm}15.37$ for medication adherence. The direct effect of depression on medication adherence was not statistically significant, but the indirect effects of depression mediated with self-efficacy and belief about medication were statistically significant. Conclusion: It is necessary to develop and apply a nursing intervention program that can not only relieve depression but also promote self-efficacy and the belief about medication with the objective of improving medication adherence among patients with systemic lupus erythematosus.

Keywords

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