Progress in Medical Physics (한국의학물리학회지:의학물리)

Korean Society of Medical Physics (한국의학물리학회)
권호 표지
DOI QR코드

DOI QR Code

Initial Experience of Patient-Specific QA for Wobbling and Line-Scanning Proton Therapy at Samsung Medical Center

  • Jo, Kwanghyun (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Ahn, Sung Hwan (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Chung, Kwangzoo (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Cho, Sungkoo (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Shin, Eun Hyuk (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Park, Seyjoon (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Hong, Chae-Seon (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Dae-Hyun (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Boram (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Woojin (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Choi, Doo Ho (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lim, Do Hoon (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Pyo, Hong Ryull (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Han, Youngyih (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Received : 2018.12.14
  • Accepted : 2019.03.12
  • Published : 2019.03.31
Download PDF
⟨ Previous Next ⟩

Abstract

Purpose: To report the initial experience of patient-specific quality assurance (pQA) for the wobbling and line-scanning proton therapy at Samsung Medical Center. Materials and Methods: The pQA results of 89 wobbling treatments with 227 fields and 44 line-scanning treatments with 118 fields were analyzed from December 2015 to June 2016. For the wobbling method, proton range and spread-out Bragg peak (SOBP) width were verified. For the line-scanning method, output and two-dimensional dose distribution at multiple depths were verified by gamma analysis with 3%/3 mm criterion. Results: The average range difference was -0.44 mm with a standard deviation (SD) of 1.64 mm and 0.1 mm with an SD of 0.53 mm for the small and middle wobbling radii, respectively. For the line-scanning method, the output difference was within ${\pm}3%$. The gamma passing rates were over 95% with 3%/3 mm criterion for all depths. Conclusions: For the wobbling method, proton range and SOBP width were within the tolerance levels. For the line-scanning method, the output and two-dimensional dose distribution showed excellent agreement with the treatment plans.

Keywords

References

  1. PTCOG-PTCOG Patient Statistics. Ptcogch. 2017. URL: https://www.ptcog.ch/index.php/ptcog-patient-statistics.
  2. Chang JY, Zhang X, Wang X, Kang Y, Riley B, Bilton S, Mohan R, Komaki R, Cox JD. Significant reduction of normal tissue dose by proton radiotherapy compared with threedimensional conformal or intensity-modulated radiation therapy in Stage I or Stage III non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2006;65:1087-96. https://doi.org/10.1016/j.ijrobp.2006.01.052
  3. Hall EJ. Intensity-modulated radiation therapy, protons, and the risk of second cancers. Int J Radiat Oncol Biol Phys. 2006;65:1-7. https://doi.org/10.1016/j.ijrobp.2006.01.027
  4. Paganetti H. Range uncertainties in proton therapy and the role of Monte Carlo simulations. Phys Med Biol. 2012;57:R99-117. https://doi.org/10.1088/0031-9155/57/11/R99
  5. Lomax AJ, Bohringer T, Bolsi A, Coray D, Emert F, Goitein G, Jermann M, Lin S, Pedroni E, Rutz H, Stadelmann O, Timmermann B, Verwey J, Weber DC. Treatment planning and verification of proton therapy using spot scanning: initial experiences. Med Phys. 2004;31:3150-7. https://doi.org/10.1118/1.1779371
  6. Furukawa T, Inaniwa T, Hara Y, Mizushima K, Shirai T, Noda K. Patient-specific QA and delivery verification of scanned ion beam at NIRS-HIMAC. Med Phys. 2013;40:121707. https://doi.org/10.1118/1.4828845
  7. Mackin D, Zhu XR, Poenisch F, Li H, Sahoo N, Kerr M, Holmes C, Li Y, Lii M, Wu R, Suzuki K, Gillin MT, Frank SJ, Grosshans D, Zhang X. Spot-scanning proton therapy patient-specific quality assurance: results from 309 treatment plans. Int J Part Ther. 2014;1:711-20. https://doi.org/10.14338/IJPT-14-00017.1
  8. Zhu XR, Poenisch F, Song X, Johnson JL, Ciangaru G, Taylor MB, Lii M, Martin C, Arjomandy B, Lee AK, Choi S, Nguyen QN, Gillin MT, Sahoo N. Patient-specific quality assurance for prostate cancer patients receiving spot scanning proton therapy using single-field uniform dose. Int J Radiat Oncol Biol Phys. 2011;81:552-9. https://doi.org/10.1016/j.ijrobp.2010.11.071
  9. Mackin D, Li Y, Taylor MB, Kerr M, Holmes C, Sahoo N, Poenisch F, Li H, Lii J, Amos R, Wu R, Suzuki K, Gillin MT, Zhu XR, Zhang X. Improving spot-scanning proton therapy patient specific quality assurance with HPlusQA, a second-check dose calculation engine. Med Phys. 2013;40:121708. https://doi.org/10.1118/1.4828775
  10. Chung K, Han Y, Kim J, Ahn SH, Ju SG, Jung SH, Chung Y, Cho S, Jo K, Shin EH, Hong CS, Shin JS, Park S, Kim DH, Kim HY, Lee B, Shibagaki G, Nonaka H, Sasai K, Koyabu Y, Choi C, Huh SJ, Ahn YC, Pyo HR, Lim DH, Park HC, Park W, Oh DR, Noh JM, Yu JI, Song S, Lee JE, Lee B, Choi DH. The first private-hospital based proton therapy center in Korea; status of the Proton Therapy Center at Samsung Medical Center. Radiat Oncol J. 2015;33:337-43. https://doi.org/10.3857/roj.2015.33.4.337
  11. Yonai S, Kanematsu N, Komori M, Kanai T, Takei Y, Takahashi O, Isobe Y, Tashiro M, Koikegami H, Tomita H. Evaluation of beam wobbling methods for heavy-ion radiotherapy. Med Phys. 2008;35:927-38. https://doi.org/10.1118/1.2836953
  12. Torikoshi M, Minohara S, Kanematsu N, Komori M, Kanazawa M, Noda K, Miyahara N, Itoh H, Endo M, Kanai T. Irradiation system for HIMAC. J Radiat Res. 2007;48 Suppl A:A15-25. https://doi.org/10.1269/jrr.48.A15
  13. Haberer T, Becher W, Schardt D, Kraft G. Magnetic scanning system for heavy ion therapy. Nucl Instrum Methods Phys Res A. 1993;330:296-305. https://doi.org/10.1016/0168-9002(93)91335-K
  14. St Clair WH, Adams JA, Bues M, Fullerton BC, La Shell S, Kooy HM, Loeffler JS, Tarbell NJ. Advantage of protons compared to conventional X-ray or IMRT in the treatment of a pediatric patient with medulloblastoma. Int J Radiat Oncol Biol Phys. 2004;58:727-34. https://doi.org/10.1016/S0360-3016(03)01574-8
  15. Low DA, Dempsey JF. Evaluation of the gamma dose distribution comparison method. Med Phys. 2003;30:2455-64. https://doi.org/10.1118/1.1598711
  16. Arjomandy B, Sahoo N, Ding X, Gillin M. Use of a twodimensional ionization chamber array for proton therapy beam quality assurance. Med Phys. 2008;35:3889-94. https://doi.org/10.1118/1.2963990
  17. Arjomandy B, Sahoo N, Ciangaru G, Zhu R, Song X, Gillin M. Verification of patient-specific dose distributions in proton therapy using a commercial two-dimensional ion chamber array. Med Phys. 2010;37:5831-7. https://doi.org/10.1118/1.3505011