The Journal of the Acoustical Society of Korea (한국음향학회지)

The Acoustical Society of Korea (한국음향학회)
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A development of a multimodal patch-type probe for measuring blood flow and oxygen saturation in carotid artery

경동맥 혈류 속도 및 산소 포화도 측정을 위한 다중모드 패치형 프로브 개발

  • 윤상연 (대구경북과학기술원 정보통신융합전공) ;
  • 이기준 (대구경북과학기술원 기초학부) ;
  • 김재관 (광주과학기술원 의생명공학과) ;
  • 황재윤 (대구경북과학기술원 정보통신융합전공)
  • Received : 2019.05.17
  • Accepted : 2019.06.24
  • Published : 2019.07.31
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Abstract

To protect the patient's internal organs when a patient with cardiovascular disease occurs, it is important to reduce the elapsed time by providing emergency medical services. Decisions for conducting cardiopulmonary resuscitation are mainly made using the carotid palpation method, which directs the pulse of the carotid artery, which can diagnose the patient's condition according to one's own subject and cause cerebral blood flow to be blocked by excessive pressure in the carotid due to the weaken cardiopulmonary function. In this study, we developed a multimodal patch-type probe based on multi-channel ultrasound Doppler pairs and oxygen saturation measurement modules which can monitor cardiopulmonary functions. From the in-vivo experiments, the developed probe can be utilized as a novel tool that can increase the survival rate of cardiovascular disease patients by objectively monitoring the cardiopulmonary function of the patient quantitatively and promptly in an emergency situation.

심혈관계 질환 환자가 발생 하였을 때, 환자의 뇌와 내부 장기를 보호하고 생존율을 높이기 위해서는 사건발생 이후 신속하게 응급 의료 서비스를 제공하여 경과 시간을 줄이는 것이 가장 중요하다. 뿐만 아니라 심폐소생술의 실시를 위한 판단은 경동맥의 맥을 직접 짚는 '경동맥 촉진법'은 실시자의 주관적인 판단과 약해진 심혈관 기능에 따른 뇌혈류 차단을 할 수 있다. 본 연구는 개발된 다중 초음파 도플러 채널 쌍과 산소포화도 측정 모듈이 결합된 패치형 프로브를 이용하여 경동맥의 혈류 속도, 맥박, 산소포화도를 생체 내 실험을 통해 정성적으로 측정하였다. 따라서 본 시스템은 응급 상황에서 정량적이고 신속하게 환자의 심폐 기능을 모니터링 하여 심폐소생술 판단 여부를 객관적으로 제공하여 응급 상황 시 심혈관계 질환 환자의 생존률을 높일 수 있는 차세대 진단 기기로 활용 될 수 있다.

Keywords

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Fig. 1. Conceptual diagram of a developed multimodal patch-type probe system.

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Fig. 3. Measured impulse response profiles for each fabricated ultrasound Doppler transducer elements.

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Fig. 4. Doppler spectrum measured by (a) commercial diagnosis equipment and (b) developed multimodal patch-type probe.

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Fig. 5. The intensity profile of red and infrared obtained by each pulse oximeter channels (a) and measured heart rate and SpO2 information.

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Fig. 2. (a) Conceptual design diagram and (b) Photograph of an ultrasound Doppler transducer elements and multimodal patch-type probe.

Table 1. Acoustic properties for fabricated 5 MHz single element transducers.

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References

  1. J. Xu, K. D. Kochanek, S. L. Murphy, and B. Tejada-Vera, "Deaths: final data for 2014," Natl Vital Stat Rep., 65, 1-122 (2016).
  2. D. Mozaffarian, E. J. Benjamin, A. S. Go, D. K. Arnett, M. J. Blaha, M. Cushman, S. R. Das, S. Ferranti, J. P. Després, H. J. Fullerton, V. J. Howard, M. D. Huffman, C. R. Isasi, M. C. Jimenez, S. E. Judd, B. M. Kissela, J. H. Lichtman, L. D. Lisabeth, S. Liu, R. G. Mackey, D. J. Magid, D. K. McGuire, E. R. Mohler, C. S. Moy, P. Muntner, M. E. Mussolino, K. Nasir, R. W. Neumar, G. Nichol, L. Palaniappan, D. K. Pandey, M. J. Reeves, C. J. Rodriguez, W. Rosamond, P. D. Sorlie, J. Stein, A. Towfighi, T. N. Turan, S. S. Virani, D. Woo, R. W. Yeh, and M. B. Turner, "Heart disease and stroke statistics-2016 update a report from the American Heart Association," Circulation, 133.4, e38-e48 (2016). https://doi.org/10.1161/CIR.0000000000000350
  3. G. Lombardi and E. J. Gallagher, "Outcome of outof- hospital cardiac arrest in New York City: the prehospital arrest survival evaluation (PHASE) study," JAMA. 271, 678-683 (1994). https://doi.org/10.1001/jama.1994.03510330056034
  4. G. Sanson, J. Verduno, M. Zambon, R. Trevi, G. D. Caggegi, and S. D. Bartolomeo, "Emergency medical service treated out-of-hospital cardiac arrest: Identification of weak links in the chain-of-survival through an epidemiological study," Eur. J. Cardiovasc. Nurs. 15, 328-336 (2016). https://doi.org/10.1177/1474515115573365
  5. R. O. Cummins and M. F. Hazinski, "Cardiopulmonary resuscitation techniques and instruction: when does evidence justify revision?," Annals of Evergency Mdeicine, 34, 780-784 (1999).
  6. J. Clawson, C. Olola, G. Scott, A. Heward, and B. Patterson, "Effect of a medical priority dispatch system key question addition in the seizure/convulsion/fitting protocol to improve recognition of ineffective (agonal) breathing," Resuscitation, 79, 257-264 (2008). https://doi.org/10.1016/j.resuscitation.2008.06.006
  7. A. Heward, M. Damiani, and C. Hartley-Sharpe, "Does the use of the advanced medical priority dispatch system affect cardiac arrest detection?," Emerg. Med. J., 21, 115-118 (2004). https://doi.org/10.1136/emj.2003.006940
  8. M. S. Eisenberg, A. P. Hallstrom, W. B. Carter, R. O. Cummins, L. Bergner, and J. Pierce, "Emergency CPR instruction via telephone," Am. J. Public Health. 75, 47-50 (1985). https://doi.org/10.2105/AJPH.75.1.47
  9. M. E. Kleinman, E. E. Brennan, Z. D. Goldberger, R. A. Swor, M. Terry, B. J. Bobrow, R. J. Gazmuri, A. H. Travers, and T. Rea, "Part 5: Adult basic life support and cardiopulmonary resuscitation quality," Circulation, 132, S414-S435 (2015). https://doi.org/10.1161/CIR.0000000000000259
  10. J. L. McDonald, "Systolic and mean arterial pressures during manual and mechanical CPR in humans," Ann Emerg. Med. 11, 292-295 (1982). https://doi.org/10.1016/S0196-0644(82)80125-X
  11. Q. Zhou, K. H. Lam, H. Zheng. W. Qiu, and K. K. Shung, "Piezoelectric single crystal ultrasonic transducers for biomedical applications," Progress in Materials Science, 66, 87-111 (2014). https://doi.org/10.1016/j.pmatsci.2014.06.001
  12. T. L. Szabo, Diagnostic Ultrasound Imaging: Inside Out (Boston, Academic Press, 2004), pp. 442-448.
  13. J. A. Jensen, Estimation of Blood Velocities using Ultrasound: A Signal Processing Approach (Cambridge University Press, 1996), pp. 111-121.