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모 지역의 소아 백혈병 및 악성림프종 발병 사례와 환경적 요인의 연관성 조사

Association of the Risk of Leukemia and Non-Hodgkin's Lymphoma (NHL) with Environmental Agents

  • 박동욱 (한국방송통신대학교 환경보건학과) ;
  • 최상준 (대구가톨릭대학교 산업보건학과) ;
  • 윤간우 (노동환경건강연구소) ;
  • 김소연 (한국방송통신대학교 환경보건학과) ;
  • 김희윤 (경희대학교 사회학과) ;
  • 박윤경 (대구가톨릭대학교 산업보건학과) ;
  • 김원 (노동환경건강연구소) ;
  • 임상혁 (노동환경건강연구소) ;
  • 박지훈 (서울대학교 보건환경연구소)
  • Park, Dong-Uk (Department of Environmental Health, Korea National Open University) ;
  • Choi, Sangjun (Department of Occupational Health, Daegu Catholic University) ;
  • Youn, Kanwoo (Wonjin Institute for Occupational and Environmental Health) ;
  • Kim, So-Yeon (Department of Environmental Health, Korea National Open University) ;
  • Kim, Hee-Yun (Department of Sociology, Kyunghee University) ;
  • Park, Yun-Kyung (Department of Occupational Health, Daegu Catholic University) ;
  • Kim, Won (Wonjin Institute for Occupational and Environmental Health) ;
  • Iim, Sanghyuk (Wonjin Institute for Occupational and Environmental Health) ;
  • Park, Jihoon (Institute of Health and Environment, Graduate School of Public Health, Seoul National University)
  • 투고 : 2019.05.29
  • 심사 : 2019.06.17
  • 발행 : 2019.06.30

초록

Objective: A total of five students at same middle school were reported to be diagnosed with pediatric leukemia (n=2), non-Hodgkin's lymphoma (NHL, n=1) and aplastic anemia (n=2) between 2016 and 2017. The aims of this study are to assess exposure to environmental hazardous agents known to be associated with the risk of leukemia and to examine whether the environment of school is associated with the risk leukemia. Method: A total of 11 environmental agents causing childhood leukemia were monitored using international certified method in schools where patients had ever attended. Radon & Thoron detector was used to monitor real-time airborne radon and thoron level ($Bq/m^3$). Clinician interviewed two among nine patients who agreed to participate in this study in order to examine the association of demographic and genetic factors by individually. Leukemia, NHL, and aplastic anemia were grouped into lymphohematopoietic disorder (LHP). Results: Except for airborne radon level, no environmental agents in school and household where patients may be exposed were found to higher than recommended airborne level. Clinical investigation found no individual factors that may be associated with the risk of LHP. Higher airborne radon level than Korea EPA's airborne radon criteria ($148Bq/m^3$) was monitored at most of several after-class room of one elementary school, where two leukemia patients graduated. Significant radon level was not monitored at class-room. Significant exposure to radon of patients was not estimated based on time-activity pattern. Conclusions: Our results have concluded that there have been no environmental factors in school and household environment that may be associated the risk of LHP.

키워드

참고문헌

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