Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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Symptomatic Hypocalcemia Associated with Dioscorea tokoro Toxicity

도코로(Tokoro)마 중독과 관련한 저 칼슘혈증

  • Yoon, Jae Chol (Department of Emergency Medicine, Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital) ;
  • Lee, Jae Baek (Department of Emergency Medicine, Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital) ;
  • Jeong, Tae Oh (Department of Emergency Medicine, Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital) ;
  • Jo, Si On (Department of Emergency Medicine, Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital) ;
  • Jin, Young Ho (Department of Emergency Medicine, Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital)
  • 윤재철 (전북대학교 의학전문대학원 응급의학교실 및 전북대학교 임상의학 연구소/전북대학교병원 의생명 연구원) ;
  • 이재백 (전북대학교 의학전문대학원 응급의학교실 및 전북대학교 임상의학 연구소/전북대학교병원 의생명 연구원) ;
  • 정태오 (전북대학교 의학전문대학원 응급의학교실 및 전북대학교 임상의학 연구소/전북대학교병원 의생명 연구원) ;
  • 조시온 (전북대학교 의학전문대학원 응급의학교실 및 전북대학교 임상의학 연구소/전북대학교병원 의생명 연구원) ;
  • 진영호 (전북대학교 의학전문대학원 응급의학교실 및 전북대학교 임상의학 연구소/전북대학교병원 의생명 연구원)
  • Received : 2019.03.15
  • Accepted : 2019.05.29
  • Published : 2019.06.30
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Abstract

Dioscorea tokoro has long been used in Korean traditional medicine as a pain killer and anti-inflammatory agent. A 53-year-old male who consumed water that had been boiled with raw tubers of D. tokoro as tea presented with numbness and spasm of both hands and feet. Laboratory results showed hypocalcemia, hypoparathyroidism, and vitamin D insufficiency. During his hospital stay, colitis, acute kidney injury, and toxic encephalopathy developed. The patient received calcium gluconate intravenous infusion and oral calcium carbonate with alfacalcidol. His symptoms improved gradually, but hypocalcemia persisted despite the calcium supplementation. We suggest that ingestion of inappropriately prepared D. tokoro can cause symptomatic hypocalcemia in patients with unbalanced calcium homeostasis.

Keywords

References

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