Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
권호 표지
DOI QR코드

DOI QR Code

Elicitor-treated extracts of Saururus chinensis inhibit the expression of inducible nitric oxide synthase and cyclooxygenase-2 enzyme expression in Raw cells for suppression of inflammation

  • Lee, Eun-Ho (School of Food Science and Biotechnology/Food and Bio-Industry Research Institute, Kyungpook National University) ;
  • Park, Hye-Jin (School of Food Science and Biotechnology/Food and Bio-Industry Research Institute, Kyungpook National University) ;
  • Kim, Dong-Hee (National Development Institute of Korean Medicine) ;
  • Jung, Hee-Young (School of Applied Biosciences, Kyungpook National University) ;
  • Kang, In-Kyu (Department of Horticultural Science, Kyungpook National University) ;
  • Cho, Young-Je (School of Food Science and Biotechnology/Food and Bio-Industry Research Institute, Kyungpook National University)
  • Received : 2019.04.03
  • Accepted : 2019.04.17
  • Published : 2019.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Elicitor treatment was performed to increase the anti-inflammatory activity of useful biological sources. The result showed that elicitor-treated Saururus chinensis leaf extracts positively affected nitric oxide (NO) production, and the expression of inducible NO synthase and cyclooxygenase-2 compared to extracts not exposed to elicitor treatment. This finding identified elicitor treatment as a suitable strategy for increasing the biological activity of S. chinensis. Therefore, elicitor-treated S. chinensis is useful both as health functional and medicinal materials.

Keywords

References

  1. Kwon SA (1999a) A second series about Saururus chinensis and Houttuynia cordata Thunberg. J Kor Oriental Drug 2: 18-20
  2. Kwon SA (1999b) A second series about Saururus chinensis and Houttuynia cordata Thunberg. J Kor Oriental Drug 3: 28-31
  3. Park JH, Lee CK (2000) In The encyclopedia of medicinal plants. Shinilbook Publishing Co., Korea
  4. Kwon SH (1996) The isolation of anti-hepatotoxic constituents from Saururus chinensis. MS Thesis, Seoul national university, Korea
  5. Lee ST, Lee YH, Choi YJ, Lee YH, Choi JS, Heo JS (2001) Yield and bioactive component on different compostamounts and culture method of Saururus chinensis Bail. Kor J Med Crop Sci 9: 220-224
  6. Lee ST, Park JM, Lee HK, Kim MB, Cho JS, Heo JS (2000) Component comparison in different growth stages and organs of Saururus chinensis Bail. Kor J Med Crop Sci 8: 312-318
  7. Kim BH, Song WS (2000) The dyeability and antimicrobial activity of Saururus chinensis (I). J Kor I lomc Economics 38: 1-9
  8. Jhoo JW (2008) Anti-inflammatory effects of purpurogallin carboxylic acid, an oxidation product of gallic acid in fermented tea. Kor J Food Sci technol 40: 707-711
  9. Cho YJ, Park SY, Kim KB (2014) Cultivation method of increased inhibitory compounds in Saurrus chinensis by yeast to enzyme degradation. Patent 10-1469901, Korea
  10. Park SY, Song IH, Cho YJ (2018) Elicitor treatment potentiates the preventive effect of Saururus chinensis leaves on stress-induced gastritis. Appl Biol Chem 61: 423-431 https://doi.org/10.1007/s13765-018-0375-3
  11. Cho YJ, Ju IS, Chun SS, An BJ, Kim JH, Kim MU, Kwon OJ (2008) Screening of biological activities of extracts from Rhododendron mucronulatum turcz. flowers. J Kor Soc Food Sci Nutr 37: 276-281 https://doi.org/10.3746/jkfn.2008.37.3.276
  12. Joo EY, Lee YS, Kim NW (2007) Polyphenol compound contents and physiological activities in various extracts of the Vitex rotundifolia stems. J Kor Soc Food Sci Nutr 36: 813-818 https://doi.org/10.3746/jkfn.2007.36.7.813
  13. Makins R, Ballinger A (2004) Gastrointestinal side effect of drugs. Expert Opin Drug Saf 2: 421-429 https://doi.org/10.1517/14740338.2.4.421
  14. Jeong HJ, Lee KY, Hong SY, HEO NK, Kim HY (2013) Antiinflammatory effects of Xanthoceras sorbifolia seeds oil on Raw 264.7 macrophages and TPA-induced ear edema mice. J Forest Sci 29: 324-330
  15. Willeaume V, Kruys V, Mijatovic T, Huez G (1995) Tumer necrosis factor-alpha production induced by viruses and by lipopolysaccharides in macrophages: similarities and differences. J Inflamm 46: 1-12
  16. Walsh NC, Crotti TN, Goldring SR, Gravallese EM (2005) Rheumatic diseases: the effects of inflammation on bone. Immunol Rev 208: 228-251 https://doi.org/10.1111/j.0105-2896.2005.00338.x
  17. Duval B, Shetty K (2001) The stimulation of phenolics and antioxidant activity in pea (Pisum sativum) elicited by genetically transformed Anise root extract. J Food Biochem 25: 361-377 https://doi.org/10.1111/j.1745-4514.2001.tb00746.x
  18. Carmichael J, DeGraff WG, Gazdar AF, Minna JD, Mitchell JB (1987) Evaluation of a tetrazolium based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 47: 936-942
  19. Cho YJ, An BJ (2008) Anti-inflammatory effect of extracts from Cheongmoknosang (Morus alba L.) in lopopolysaccharide-stimulated Raw cells. J Kor Soc Appl Biol Chem 51: 44-48
  20. Ryu JH, Ahn H, Kim JY, Kim YK (2003) Inhibitory activity of plant extracts on nitric oxide synthesis in LPS-activated macrophage. Phyto Res 17: 485-489 https://doi.org/10.1002/ptr.1180
  21. Cho YJ (2011) Anti-inflammatory effect of Jatrorrhizine from Phellodendron amurense in Lipopolysaccharide-stimulated Raw 264.7 cells. J Appl Biol Chem 54: 114-119 https://doi.org/10.3839/jabc.2011.020
  22. Syu-ichi K, Ai S, Ayako T, Takako H, Yu O, Mayuko U, Yutaro O, Norimichi N, Masaaki I (2005) Inhibitory effect of naringin on lipopolysaccharide (LPS)- induced endotoxin shock in mice and nitric oxide production in Raw 264.7 macrophages. Life Sci 25: 1-9
  23. Kim MK, Kim DY (2015) Anti-inflammatory effect of barley leaf ethanol extract in LPS-stimulated RAW264.7 macrophage. Kor J Food Preserv 22: 735-743 https://doi.org/10.11002/kjfp.2015.22.5.735
  24. Kim DH, Cho JH, Cho YJ (2016) Anti-inflammatory activity of extracts from ultra-fine ground Saururus chinensis leaves in lipopolysaccharidestimulated Raw 264.7 cells. J Appl Biol Chem 59: 37-43 https://doi.org/10.3839/jabc.2016.008
  25. Kim NK, Kim MH, Yoon CS, Choi SW (2006) Studies on the antiinflammatory activity of Paulownia coreana Uyeki leaf extracts. J Soc Cosmet Sci Kor 32: 241-247
  26. Lee SJ, Lee DG, Kim MY, Kong SC, Yu KH, Kim YY, Lee SH (2016) Enhancement of anti-inflammatory activity by fermentation of Sargassum siliquanstrum. J Life Sci 26: 318-324 https://doi.org/10.5352/JLS.2016.26.3.318
  27. Park SJ, Shin JS, Cho W, Cho YW, Ahn EM, Baek NI (2008) Inhibition of LPS induced iNOS, COX-2 and cytokines expression by kaempferol-3-O-${\beta}$-D-sophoroside through the NF-aB inactivation in RAW 264.7 cells. Kor J Pharmacogn 39: 95-103
  28. Park SJ, Kim JY, Jang YP, Cho YW, Ahn EM, Baek NI (2007) Inhibition of LPS induced iNOS, COX-2 and cytokines expression by genistein-4'-O-a-L-rhamno pyranosyl-(1-2)-a-D-glucopyrano side through the NF-eB inactivation in Raw 264.7 Cells. Kor J Pharmacogn 38: 339-348
  29. Jung YS, Eun CS, Jung YT, Kim HJ, Yu MH (2013) Anti-inflammatory effects of Picrasma quassioides BENN leaves extracts. J Life Sci 23: 629-636 https://doi.org/10.5352/JLS.2013.23.5.629

Cited by

  1. Fabrication and characterization of Agarwood extract-loaded nanocapsules and evaluation of their toxicity and anti-inflammatory activity on RAW 264.7 cells and in zebrafish embryos vol.28, pp.1, 2019, https://doi.org/10.1080/10717544.2021.2012307
  2. Responses of inflammation signaling pathway by saucerneol D from elicitor-treated Saururus chinensis on pro-inflammatory responses in LPS-stimulated Raw 264.7 cell vol.64, pp.1, 2019, https://doi.org/10.1186/s13765-020-00585-z